KEGG   Gallus gallus (chicken): 424971Help
Entry
424971            CDS       T01006                                 

Gene name
PIK3CA, C-P3K
Definition
phosphoinositide-3-kinase, catalytic, alpha polypeptide (EC:2.7.1.153)
Orthology
K00922  
phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
Organism
gga  Gallus gallus (chicken)
Pathway
Inositol phosphate metabolism
ErbB signaling pathway
FoxO signaling pathway
Phosphatidylinositol signaling system
mTOR signaling pathway
Apoptosis
Adrenergic signaling in cardiomyocytes
VEGF signaling pathway
Focal adhesion
Toll-like receptor signaling pathway
Jak-STAT signaling pathway
Regulation of actin cytoskeleton
Insulin signaling pathway
Progesterone-mediated oocyte maturation
Influenza A
Brite
KEGG Orthology (KO) [BR:gga00001]
 Metabolism
  Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    424971 (PIK3CA)
 Environmental Information Processing
  Signal transduction
   04012 ErbB signaling pathway
    424971 (PIK3CA)
   04370 VEGF signaling pathway
    424971 (PIK3CA)
   04630 Jak-STAT signaling pathway
    424971 (PIK3CA)
   04068 FoxO signaling pathway
    424971 (PIK3CA)
   04070 Phosphatidylinositol signaling system
    424971 (PIK3CA)
   04150 mTOR signaling pathway
    424971 (PIK3CA)
 Cellular Processes
  Cell motility
   04810 Regulation of actin cytoskeleton
    424971 (PIK3CA)
  Cell growth and death
   04210 Apoptosis
    424971 (PIK3CA)
  Cell communication
   04510 Focal adhesion
    424971 (PIK3CA)
 Organismal Systems
  Immune system
   04620 Toll-like receptor signaling pathway
    424971 (PIK3CA)
  Endocrine system
   04910 Insulin signaling pathway
    424971 (PIK3CA)
   04914 Progesterone-mediated oocyte maturation
    424971 (PIK3CA)
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    424971 (PIK3CA)
 Human Diseases
  Infectious diseases
   05164 Influenza A
    424971 (PIK3CA)
Enzymes [BR:gga01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.153  phosphatidylinositol-4,5-bisphosphate 3-kinase
     424971 (PIK3CA)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
CGNC: 
Ensembl: 
UniProt: 
Position
9
AA seq 1068 aa AA seqDB search
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPICEFDMVKDPEVQDFRRNILNVCKEAVDLRDANAPHSRALYVCPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEATAKSLWTINSALRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLSYDMYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWAVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SNPVKFPDMTVIEEHANWTISRELGFNYSYAGLSNRIARDNELRESDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVNTPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRAFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNQLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
NT seq 3207 nt NT seq  +upstreamnt  +downstreamnt
atgccaccccgaccatcatctggtgaactatggggcatccacttgatgcccccgaggatc
cttgtggagtgtcttctcccaaatggaatgatagtgactctagaatgcctccgtgaggcc
acactgctaactatcaaacatgaactttttaaagaagcaagaaaataccctctctatcag
ctccttcaagatgaatcttcttacatttttgtaagtgttacgcaagaagcagaaagagaa
gaattttttgatgaaacacggagactttgtgacctgcggctatttcaacctttcctaaaa
gtcattgaaccagtaggtaacagagaagaaaagatccttaatagagaaataggttttgct
attggcatgcccatctgtgagtttgacatggttaaggatcctgaagtacaagatttcaga
agaaacattcttaatgtttgtaaagaagcagtagatcttcgagatgccaatgctccacat
agtagagcattatatgtctgtcctccaaatgtagaatcttcacctgagctacccaaacac
atatacaataaactagataaagggcaaataatagtggtgatatgggtaatagtttcacct
aacaacgataagcagaagtacaccttaaaaatcaatcatgactgtgtgcctgagcaagtt
attgctgaagcaattaggaagaaaacacgaagtatgttgctgtcatctgaacaactgaag
ctttgcgtgttggagtaccagggcaagtatattctgaaagtgtgtggctgtgatgaatac
ttgctagaaaaatatccactgagccagtataagtacataagaagttgtataatgcttggt
cgcatgcccaatctcatgctgatggctaaagaaagcctatatacccagctgccgctcgat
acctttacaatgccatcttactccaggcgtatctctacagctacaccctacatgaatgga
gaagctacagccaagtccctctggactataaacagtgctctcagaataagaatcctctgt
gcaacctatgtaaatgtgaacattagagacattgacaaaatctacgttagaacaggtatc
taccatggaggagaacctttatgtgacaatgtgaatactcagagggtaccttgttctaat
cccagatggaatgaatggctgtcgtatgacatgtacattcctgatcttccacgtgctgct
cggctctgcctctctatctgttctgttaaaggccggaagggtgctaaagaggagcactgt
ccattggcttggggaaacataaacatgtttgactacacggacactcttgtatctgggaaa
atggctttgaatctttgggcagtaccccatggactggaggatttgttgaatcctataggt
gttactggatcaaatccgaataaggaaactccatgtttagagctggaatttgattggttt
agcaatcctgttaagtttccagatatgacagtgattgaagaacatgccaattggacgatc
tcacgtgaactgggctttaactacagctatgcgggactgagtaacagaatagctagagac
aatgaattaagagaaagtgacaaggagcaactgagagccatatgtacgcgagatcctttg
tctgaaatcactgagcaagagaaggacttcctctggagccacagacactattgtgtaaat
acgccagaaattctgcccaaattacttctgtctgttaaatggaattctagagatgaagtg
gctcagatgtactgtttggtaaaagattggcctccaatcaagccagagcaagcaatggag
cttttggattgtaattatccagatccaatggtgcgggcttttgcagttcggtgtctagag
aagtacttaacagatgacaaactgtctcagtacttaatccagctagtacaggttctgaaa
tatgagcagtacttagataatcaactcgtgagatttttactcaagaaggcactgaccaat
caacggataggacacttcttcttttggcatttaaagtctgaaatgcacaataaaactgta
agtcagaggtttggtttacttctggagtcctattgtcgagcatgtggaatgtacctaaag
catctgagcaggcaggtggaggctatggagaagttgattaacctcacagatattctcaag
caggaaaagaaagatgagacccagaaggtgcagatgaagtttcttgttgaacaaatgaga
cgtccagattttatggatgctttacaaggctttatctctcctcttaatcctgctcatcaa
ctgggaaatcttcggcttgaggagtgcagaataatgtcatctgcaaaaaggcccctgtgg
ttaaactgggaaaacccagatattatgtctgaattgctatttcagaacaatgagataatc
tttaaaaatggagatgacttgcgtcaagacatgctgacacttcagataattagaattatg
gaaaacatctggcaaaaccaaggtcttgatcttcggatgttgccttacggttgtttgtct
attggtgactgtgtgggactcattgaggtagtgagaagttctcatacaatcatgcagatt
cagtgtaaaggaggcttaaagggagcattgcagttcaacagccatacattgcatcagtgg
ctcaaggacaagaacaaaggagaaatgtatgatgcagctattgacttgtttacacgttct
tgtgctggctactgtgtcgctacctttatactgggcattggtgatcgccacaacagtaac
atcatggtgaaagatgatggacaactgtttcatattgactttggccacttccttgaccac
aagaagaagaaatttggctacaaaagagagcgtgtgccctttgtcttaacacaggacttt
ttaatagtgattagtaaaggagcccaagaatgtaccaaaacaagggagtttgaaaggttt
caagagatgtgttataaggcatatctagcaattcggcagcatgccaatctgttcataaat
ctcttctccatgatgcttggctcaggaatgccagaactgcagtcctttgacgatattgca
tacattcgaaagacccttgcattggacaaaactgagcaggaagctcttgagtacttcatg
aagcaaatgaatgatgctcaccatggtggctggacaacaaaaatggactggatcttccac
acaataaagcaacatgctttgaactga

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