KEGG   Geobacillus sp. GHH01: GHH_c13380
Entry
GHH_c13380        CDS       T02455                                 
Symbol
iolA1
Name
(GenBank) methylmalonate semialdehyde dehydrogenase
  KO
K00140  malonate-semialdehyde dehydrogenase (acetylating) / methylmalonate-semialdehyde dehydrogenase [EC:1.2.1.18 1.2.1.27]
Organism
ggh  Geobacillus sp. GHH01
Pathway
ggh00280  Valine, leucine and isoleucine degradation
ggh00410  beta-Alanine metabolism
ggh00562  Inositol phosphate metabolism
ggh00640  Propanoate metabolism
ggh01100  Metabolic pathways
ggh01200  Carbon metabolism
Brite
KEGG Orthology (KO) [BR:ggh00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00640 Propanoate metabolism
    GHH_c13380 (iolA1)
   00562 Inositol phosphate metabolism
    GHH_c13380 (iolA1)
  09105 Amino acid metabolism
   00280 Valine, leucine and isoleucine degradation
    GHH_c13380 (iolA1)
  09106 Metabolism of other amino acids
   00410 beta-Alanine metabolism
    GHH_c13380 (iolA1)
Enzymes [BR:ggh01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.1  With NAD+ or NADP+ as acceptor
    1.2.1.18  malonate-semialdehyde dehydrogenase (acetylating)
     GHH_c13380 (iolA1)
    1.2.1.27  methylmalonate-semialdehyde dehydrogenase (CoA-acylating)
     GHH_c13380 (iolA1)
SSDB
Motif
Pfam: Aldedh LuxC
Other DBs
NCBI-ProteinID: AGE21875
UniProt: L7ZW25
Position
1324323..1325789
AA seq 488 aa
MTVTKNETTILKNFINGQWVESSGTKTLEVPNPATGEVLARVPISTKEDVDRAVQAAKKA
FETWKNTPVPKRARIMFTFHHLLNEHHEELAKLIVQENGKAYKEAYGEIQRGIECVEFAA
GAPTLMMGESLSGIAEGIDSEMFRYPLGVVAGITPFNFPMMVPLWMFPLAIACGNTFVLK
PSERTPILANKLAELFTQAGAPEGVLNIVHGAHDVVNALIDHEDIKAISFVGSQPVAKYV
YERAAAQGKRVQALSGAKNHHIVMPDADIETAVQHVISSAFGSAGQRCMACSAVVIVGEN
ERFVKLLKQKADEIVIGNGMDPEVFLTPVIRQSHREKVLGYIQKGIEEGAILIRDGRKEM
EEMREGNFLGPTIFDHVTPNMTIAKEEIFAPVLSLLRAKDLDEALEYIRKSRYGNGATIY
TKDAKAVRKFREEADAGMLGINVGVPATMAFFPFSGWKDSFYGDLHVNGKDGVNFYTRKK
MITSRFDF
NT seq 1467 nt   +upstreamnt  +downstreamnt
atgacggtgacaaagaacgaaacaactattttgaaaaactttattaatggacaatgggta
gaatcaagcgggacgaagacattggaagtgccgaatccggcgacaggggaagtgctggcg
cgggttccgatttcgacgaaggaagatgtagacagagctgtgcaagcggccaaaaaagcg
tttgaaacgtggaaaaatacaccggttcctaaacgggcgcggattatgtttacatttcat
catttattgaacgagcatcatgaagaattagcaaagcttatcgttcaagagaacggaaaa
gcatataaagaagcatatggagagattcaaaggggaattgagtgcgtagaatttgctgcg
ggcgctccaacattaatgatgggggagtcactatcgggaattgcggaaggcattgattcg
gaaatgttccgttatcctttaggagtagtcgctggaattacgccatttaattttccgatg
atggtgcctctctggatgtttccgttggcgattgcttgcgggaatacgttcgtattaaag
ccatctgaaagaacgccgattttagccaataaactggctgagttgtttacacaggccggg
gcgccagaaggagtgctcaatatcgttcatggggcgcatgatgtcgttaatgccctcatc
gatcacgaggatattaaagcaatttcttttgtcggttcccagcctgtcgccaaatatgta
tatgagcgtgcagcggcacaaggtaaacgagtgcaagcgctttctggggcaaaaaatcat
catatcgtcatgcctgatgctgatatagagacagcagtgcagcacgtgattagttccgct
tttggaagtgcaggacagcgttgcatggcttgtagcgcggttgttattgttggtgaaaat
gaacggtttgtaaaactgctaaagcaaaaggcggatgaaattgttattggaaatggtatg
gatccagaagtgtttttaacccccgttattcgccaatcccatcgtgaaaaagtattggga
tacattcaaaaggggattgaagaaggggcaatacttattcgggatggacgcaaagaaatg
gaggaaatgcgagaaggaaacttccttgggccaacgatttttgatcatgtcacaccaaat
atgacgattgctaaagaagagatttttgctcctgtccttagcttgttgcgtgccaaagat
ttggacgaagcacttgagtatattcgcaaatctcgatacggaaacggtgcgactatttat
acgaaagatgcgaaagctgtccgtaaattccgtgaagaagcggatgcgggaatgttagga
atcaatgtaggcgtaccggcaacgatggcattcttcccgttctctggctggaaggactcg
ttttatggtgacctccacgtaaatggaaaagatggagtgaacttctatacacgcaaaaaa
atgattacctctcgattcgatttttaa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical substance (12)   
   KEGG COMPOUND (12)   
Chemical reaction (6)   
   KEGG ENZYME (2)   
   KEGG REACTION (4)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (2)   
   Pfam (2)   
All databases (34)   

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