KEGG   Gorilla gorilla gorilla (western lowland gorilla): 101127850Help
Entry
101127850         CDS       T02442                                 

Gene name
SPHK1
Definition
sphingosine kinase 1 isoform 1
Orthology
K04718  
sphingosine kinase [EC:2.7.1.91]
Organism
ggo  Gorilla gorilla gorilla (western lowland gorilla)
Pathway
Sphingolipid metabolism
Metabolic pathways
Calcium signaling pathway
VEGF signaling pathway
Fc gamma R-mediated phagocytosis
Tuberculosis
Module
Sphingosine degradation
Brite
KEGG Orthology (KO) [BR:ggo00001]
 Metabolism
  Lipid metabolism
   00600 Sphingolipid metabolism
    101127850 (SPHK1)
 Environmental Information Processing
  Signal transduction
   04370 VEGF signaling pathway
    101127850 (SPHK1)
   04020 Calcium signaling pathway
    101127850 (SPHK1)
 Organismal Systems
  Immune system
   04666 Fc gamma R-mediated phagocytosis
    101127850 (SPHK1)
 Human Diseases
  Infectious diseases
   05152 Tuberculosis
    101127850 (SPHK1)
Enzymes [BR:ggo01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.91  sphinganine kinase
     101127850 (SPHK1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 
Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Position
5
AA seq 384 aa AA seqDB search
MDPAGGPRGVLPRPCRVLVLLNPRGGKGKALQLFRSHVQPLLAEAEISFTLMLTERRNHA
RELVLSEELGRWDALVVMSGDGLMHEVVNGLMERPDWETAIQKPLCSLPAGSGNALAASL
NHYAGYEQVTNEDLLTNCTLLLCRRLLSPMNLLSLHTASGLRLFSVLSLAWGFIADVDLE
SEKYRRLGEMRFTLGTFLRLAALRTYRGRLAYLPVGRVGSKTPASPVVVQQGPVDAHLVP
LEEPVPSHWTVVPDQDFVLVLALLHSHLGSEMFAAPMGRCAAGVMHLFYVRAGVSRAMLL
RLFLAMEKGRHMEYECPYLVYVPVVAFRLEPKDGKGVFAVDGELMVSEAVQGQVHPNYFW
MVSGCVEPPPSWKPQQTPPPEEPL
NT seq 1155 nt NT seq  +upstreamnt  +downstreamnt
atggatccagcgggcggcccccggggcgtgctcccgcggccctgccgcgtgctggtgctg
ctgaacccgcgcggcggcaagggcaaggccctgcagctcttccggagtcacgtgcagccc
cttttggctgaggctgaaatctccttcacgctgatgcttactgagcggcggaaccacgcg
cgggagctggtgctgtcggaggagctgggccgctgggacgctctggtggtcatgtctgga
gacgggctgatgcacgaggtggtgaacgggctcatggagcggcctgactgggagaccgcc
atccagaagcccctgtgtagcctcccagcaggctctggcaacgcgctggcagcttccttg
aaccattatgctggctatgagcaggtcaccaatgaagacctcctgaccaactgcacacta
ttgctgtgccgccggctactgtcgcccatgaacctgctgtctctgcacacggcttcgggg
ctgcgcctcttctctgtgcttagcctggcctggggcttcattgctgatgtggacctagag
agtgagaagtatcggcgtctgggggagatgcgcttcactctgggcaccttcctgcgtctg
gcagccctgcgcacctaccgtggccgattggcctacctccctgtaggaagagtcggttcc
aagacacctgcctcccccgttgtggtccagcagggcccggtagatgcacaccttgtgcca
ctggaggagccagtgccctctcactggacagtggtgcccgaccaggactttgtgctagtc
ttggcactgctgcactcgcacctgggcagtgagatgtttgctgcacccatgggccgctgt
gcagctggtgtcatgcatctgttctacgtgcgggcgggcgtgtctcgcgccatgctgctg
cgcctcttcctggccatggagaagggcaggcatatggagtatgaatgcccctacttggta
tatgtgcccgtggtcgccttccgcttggagcccaaggatgggaaaggtgtgtttgcagtg
gatggggaattgatggttagcgaggccgtgcagggccaggtgcacccaaactacttctgg
atggtcagtggttgcgtggagcccccgcccagctggaagccccagcagacgccaccgcca
gaagagcccttgtga

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