KEGG   Gorilla gorilla gorilla (western lowland gorilla): 101129357Help
Entry
101129357         CDS       T02442                                 

Gene name
PLCB3
Definition
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3
Orthology
K05858  
phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
ggo  Gorilla gorilla gorilla (western lowland gorilla)
Pathway
Inositol phosphate metabolism
Metabolic pathways
Rap1 signaling pathway
Calcium signaling pathway
Chemokine signaling pathway
Phosphatidylinositol signaling system
Adrenergic signaling in cardiomyocytes
Vascular smooth muscle contraction
Wnt signaling pathway
Gap junction
Circadian entrainment
Long-term potentiation
Retrograde endocannabinoid signaling
Glutamatergic synapse
Cholinergic synapse
Serotonergic synapse
Dopaminergic synapse
Long-term depression
Inflammatory mediator regulation of TRP channels
Insulin secretion
GnRH signaling pathway
Estrogen signaling pathway
Melanogenesis
Thyroid hormone synthesis
Thyroid hormone signaling pathway
Oxytocin signaling pathway
Endocrine and other factor-regulated calcium reabsorption
Salivary secretion
Gastric acid secretion
Pancreatic secretion
Alzheimer's disease
Huntington's disease
Chagas disease (American trypanosomiasis)
African trypanosomiasis
Amoebiasis
Module
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Class
Metabolism; Carbohydrate metabolism; Inositol phosphate metabolism [PATH:ggo00562]
Environmental Information Processing; Signal transduction; Rap1 signaling pathway [PATH:ggo04015]
Environmental Information Processing; Signal transduction; Wnt signaling pathway [PATH:ggo04310]
Environmental Information Processing; Signal transduction; Calcium signaling pathway [PATH:ggo04020]
Environmental Information Processing; Signal transduction; Phosphatidylinositol signaling system [PATH:ggo04070]
Cellular Processes; Cell communication; Gap junction [PATH:ggo04540]
Organismal Systems; Immune system; Chemokine signaling pathway [PATH:ggo04062]
Organismal Systems; Endocrine system; Insulin secretion [PATH:ggo04911]
Organismal Systems; Endocrine system; GnRH signaling pathway [PATH:ggo04912]
Organismal Systems; Endocrine system; Estrogen signaling pathway [PATH:ggo04915]
Organismal Systems; Endocrine system; Oxytocin signaling pathway [PATH:ggo04921]
Organismal Systems; Endocrine system; Thyroid hormone synthesis [PATH:ggo04918]
Organismal Systems; Endocrine system; Thyroid hormone signaling pathway [PATH:ggo04919]
Organismal Systems; Endocrine system; Melanogenesis [PATH:ggo04916]
Organismal Systems; Circulatory system; Adrenergic signaling in cardiomyocytes [PATH:ggo04261]
Organismal Systems; Circulatory system; Vascular smooth muscle contraction [PATH:ggo04270]
Organismal Systems; Digestive system; Salivary secretion [PATH:ggo04970]
Organismal Systems; Digestive system; Gastric acid secretion [PATH:ggo04971]
Organismal Systems; Digestive system; Pancreatic secretion [PATH:ggo04972]
Organismal Systems; Excretory system; Endocrine and other factor-regulated calcium reabsorption [PATH:ggo04961]
Organismal Systems; Nervous system; Glutamatergic synapse [PATH:ggo04724]
Organismal Systems; Nervous system; Cholinergic synapse [PATH:ggo04725]
Organismal Systems; Nervous system; Dopaminergic synapse [PATH:ggo04728]
Organismal Systems; Nervous system; Serotonergic synapse [PATH:ggo04726]
Organismal Systems; Nervous system; Long-term potentiation [PATH:ggo04720]
Organismal Systems; Nervous system; Long-term depression [PATH:ggo04730]
Organismal Systems; Nervous system; Retrograde endocannabinoid signaling [PATH:ggo04723]
Organismal Systems; Sensory system; Inflammatory mediator regulation of TRP channels [PATH:ggo04750]
Organismal Systems; Environmental adaptation; Circadian entrainment [PATH:ggo04713]
Human Diseases; Neurodegenerative diseases; Alzheimer's disease [PATH:ggo05010]
Human Diseases; Neurodegenerative diseases; Huntington's disease [PATH:ggo05016]
Human Diseases; Infectious diseases; Amoebiasis [PATH:ggo05146]
Human Diseases; Infectious diseases; Chagas disease (American trypanosomiasis) [PATH:ggo05142]
Human Diseases; Infectious diseases; African trypanosomiasis [PATH:ggo05143]
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Position
11
AA seq 1350 aa AA seqDB search
MRLPRSHLWNADFRAPAVGQALQSPSSTLLSGDIDKASDPSGQTTASPPRFPAKRLTAPP
RPRPARAPPRLWSVRDRLAGGRALTPRGRSGPRGGSSGAVGPRQGSVGPRPAPGRAMAGA
QPGVHALQLEPPTVVETLRRGSKFIKWDEETSSRNLVTLRVDPNGFFLYWTGPNMEVDTL
DISSIRDTRTGRYARLPKDPKIREVLGFGGPDARLEEKLMTVVSGPDPVNTVFLNFMAVQ
DDTAKVWSEELFKLAMNILAQNASRNTFLRKAYTKLKLQVNQDGRIPVKNILKMFSADKK
RVETALESCGLKFNRSESIRPDEFSLEIFERFLNKLCLRPDIDKILLEIGAKGKPYLTLE
QLMDFINQKQRDPRLNEVLYPPLRPSQARLLIEKYEPNQQFLERDQMSMEGFSRYLGGEE
NGILPLEALDLSTDMTQPLSAYFINSSHNTYLTAGQLAGTSSVEMYRQALLWGCRCVELD
VWKGRPPEEEPFITHGFTMTTEVPLRDVLEAIAETAFKTSPYPVILSFENHVDSAKQQAK
MAEYCRSIFGDALLIEPLDKYPLAPGVPLPSPQDLMGRILVKNKKRHRPSAGGPDSSGRK
RPLEQSNSALSESSAATEPSSPQLGSPSSDSCPGLSNGEEVGLEKPSLEPQKSLGDEGLN
RGPYVLGPADREDEEEDEEEEEQTDPKKPTTDEGTASSEVNATEEMSTLVNYIEPVKFKS
FEAARKRNKCFEMSSFVETKAMEQLTKSPMEFVEYNKQQLSRIYPKGTRVDSSNYMPQLF
WNVGCQLVALNFQTLDVAMQLNAGVFEYNGRSGYLLKPEFMRRPDKSFDPFTEVIVDGIV
ANALRVKVISGQFLSDRKVGIYVEVDMFGLPVDTRRKYRTRTSQGNSFNPVWDEEPFDFP
KVVLPTLASLRIAAFEEGGKFVGHRILPVSAIRSGYHYVCLRNEANQPLCLPALLIYTEA
SDYIPDDHQDYAEALINPIKHVSLMDQRARQLAALIGESEAQAGQETCQDTQSQQLGSQP
SSNPTPSPLDASPRRHPTTLSSSSSQGLCSSGQRDDLIASILSEVAPTPLDELRGHKALV
KLRSRQERDLRELRKKHQRKAVTLTRRLLDGLAQAQAEGRCRLRPGALGGAADVEDTKEG
EDEAKRYQEFQNRQVQSLLELREAQVDAEAQRRLEHLRQALQRLREVVLDANTTQFKRLK
EMNEREKKELQKILDRKRHNSISEAKMRDKHKKEAELTEINRRHITESVNSIRRLEEAQK
QRHDRLVAGQQQVLQQLAEEEPKLLAQLAQECQEQRARLPQEIRRSLLGEMPEGLGDGPL
VACASNGHAPGSSGHLSGADSESQEENTQL
NT seq 4053 nt NT seq  +upstreamnt  +downstreamnt
atgcgccttccccgctcccatctctggaacgcagatttcagggcacctgctgtgggccag
gcactgcagagcccctcctcaaccctcctgtctggggacatcgacaaagcttctgacccc
tccgggcagacaacagcgtcccccccgcggttcccagccaagaggctcacagccccgccc
cgtccccgccccgcccgggccccgccgaggctctggtcggtccgggacagactggcgggc
gggcgggcactgacgccgcggggccggagcgggccgcgcggtgggagcagcggcgccgtc
ggtccccgtcagggctccgtgggtccccgacccgcccctggccgggccatggcgggcgcc
cagcccggcgtccacgcgctgcagctggagccgcccaccgtggtggagaccctgcggcgc
gggagtaagttcatcaaatgggacgaggagacctccagtcggaacctggtgactctgcgt
gtggaccccaatggcttcttcttgtactggacgggccccaacatggaggtggacacactg
gacatcagttccatcagggacacacggacaggccggtacgcccgcctgcccaaggacccc
aagatccgggaagttctgggctttgggggtcccgatgcccggctggaggagaagctgatg
acggtggtgtctgggccagacccggtgaacacagtgttcttgaacttcatggccgtgcag
gatgacacagccaaggtctggtctgaggagctattcaagctggctatgaacatcctggct
cagaacgcctctcggaacaccttcctgcgcaaagcatacacgaagctgaagctgcaggtg
aaccaggatggtcggatccccgtcaagaacatcctgaagatgttctcagcagacaagaag
cgggtggagactgcgctggaatcctgtggcctcaaattcaaccggagtgagtccatccgg
cccgatgagttttccttggaaatctttgagcggttcctgaacaagctgtgtctgcggccg
gacattgacaagatcctgctggagataggcgccaagggcaagccatacctgacgctggag
cagctcatggacttcatcaaccagaagcaacgtgacccgagactcaacgaagtgctgtac
ccgcccctgcggccctcccaggcccggctgctcatcgaaaagtatgagcccaaccagcag
tttctggagcgagaccagatgtccatggagggctttagccgctacctgggaggcgaggag
aatggcatcctgcccctggaagccctggatctgagcacggacatgacccagccactgagt
gcctacttcatcaactcctcgcataacacctatctcactgcggggcagctggctgggacc
tcgtcggtggagatgtaccgccaggcactgctatggggctgccgctgcgtggagctggat
gtgtggaagggacggccgcccgaggaggaacccttcattacccatggcttcaccatgacc
acagaggtgcctctgcgcgacgtgctggaggccattgccgagactgccttcaagacctcg
ccctaccccgtcatcctctccttcgagaaccatgtggactcggcaaagcaacaggcaaag
atggctgagtactgccgctccatctttggagacgcgctactcatcgagcctctggacaag
tacccgctggccccaggcgttcccctgcccagcccccaggacctgatgggccgtatcctg
gtgaagaacaagaagcggcaccgacccagcgcaggtggcccagacagctccgggcgcaag
cggcccctggagcagagcaattctgccctgagtgagagctccgcggccactgagccctcc
tccccgcagcttgggtctcccagctctgacagctgcccaggcctgagcaacggggaggag
gtagggcttgagaagcccagcctggagcctcagaagtctctgggcgacgagggcctgaac
cggggcccctatgttcttggacctgctgaccgtgaggatgaggaggaagatgaagaagag
gaggaacagacagaccccaaaaagccaactacagatgagggcacagccagcagcgaggtg
aatgccactgaggagatgtccacgcttgtcaactacatcgagcctgtcaagttcaagtcc
tttgaggctgctcgaaagaggaacaaatgcttcgagatgtcgtccttcgtggagaccaag
gccatggagcaactgaccaagagccccatggagtttgtggaatacaacaagcagcagctc
agccgcatctaccccaagggcacccgcgtggactcctccaactatatgccccagctcttc
tggaacgtagggtgccagcttgttgcgctcaacttccagaccctcgatgtggcgatgcag
ctcaacgcgggcgtttttgagtacaacgggcgcagcgggtacctgctcaagccggagttc
atgcggcggccggacaagtccttcgaccccttcactgaggtcatcgtggatggcatcgtg
gccaatgccttgcgggtcaaggtgatctcagggcagttcctgtccgacaggaaggtgggc
atctacgtggaggtggacatgtttggcctccctgttgacacgcggcgcaagtaccgcacc
cggacctctcaggggaactcgttcaaccccgtgtgggacgaagagcccttcgacttcccc
aaggtggtgctgcccacgctggcttcacttcgcatcgcagcctttgaggaggggggtaaa
ttcgtagggcaccggatcctgcctgtctctgccatccgctccggataccactacgtctgc
ctgcggaacgaggccaaccaaccgctgtgcctgccggccctgctcatctacaccgaagcc
tcggactacattcctgacgaccaccaggactacgcggaggccctgatcaaccccattaag
cacgtcagcctgatggaccagagggcccggcagctggccgccctcattggagagagtgag
gctcaggctggccaagagacgtgccaggacacccagtctcagcagctggggtctcagccg
tcctcaaaccccacccctagcccactggatgcctccccccggaggcaccccaccaccctg
tcctccagctcctcacagggcctctgctcctcagggcagcgcgacgatctcatcgccagc
atcctctcagaggtggcccccaccccgctggatgagctccgaggtcacaaggctttggtc
aagctccggagccggcaagagcgagacctgcgggagctgcgcaagaagcatcagcggaag
gcagtcaccctcacccgccgcctgctggacggcctggctcaggcacaggctgagggcagg
tgccggctgcggccaggtgccctaggtggggccgctgatgtggaggacacgaaggagggg
gaggacgaggcaaagcggtatcaggagttccagaacagacaggtgcagagcctgctggag
ctgcgggaggcccaggtggacgcagaggcccagcggaggctggaacacctgagacaggct
ctgcagcggctcagggaggtcgtccttgatgcaaacacaactcagttcaagaggctgaaa
gagatgaacgagagggagaagaaggagctgcagaagatcctggacagaaagcgccataac
agcatctcggaggccaagatgagggacaagcataagaaggaggcggaactgacggagatt
aaccgtcggcacatcactgagtcagtcaactccatccgtcggctggaggaggcccagaag
cagcggcatgaccgtcttgtggctgggcagcagcaggtcctgcaacagctggcagaagag
gagcccaagctgctggcccagctggcccaggagtgtcaggagcagcgggcgaggctcccc
caggagatccgccggagcctgctgggcgagatgccggaggggctgggggacgggcctctg
gtggcctgtgccagcaacggtcatgcacccgggagcagcgggcacctgtcgggcgctgac
tcggagagccaggaggagaacacgcagctctga

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