KEGG   Gorilla gorilla gorilla (western lowland gorilla): 101134492Help
Entry
101134492         CDS       T02442                                 

Gene name
MAPK12
Definition
mitogen-activated protein kinase 12
Orthology
K04441  
p38 MAP kinase [EC:2.7.11.24]
Organism
ggo  Gorilla gorilla gorilla (western lowland gorilla)
Pathway
MAPK signaling pathway
Rap1 signaling pathway
FoxO signaling pathway
Adrenergic signaling in cardiomyocytes
VEGF signaling pathway
Osteoclast differentiation
Signaling pathways regulating pluripotency of stem cells
Platelet activation
Toll-like receptor signaling pathway
NOD-like receptor signaling pathway
RIG-I-like receptor signaling pathway
T cell receptor signaling pathway
Fc epsilon RI signaling pathway
TNF signaling pathway
Leukocyte transendothelial migration
Neurotrophin signaling pathway
Retrograde endocannabinoid signaling
Dopaminergic synapse
Inflammatory mediator regulation of TRP channels
GnRH signaling pathway
Progesterone-mediated oocyte maturation
Prolactin signaling pathway
Amyotrophic lateral sclerosis (ALS)
Salmonella infection
Pertussis
Leishmaniasis
Chagas disease (American trypanosomiasis)
Toxoplasmosis
Tuberculosis
Hepatitis C
Influenza A
Epstein-Barr virus infection
Proteoglycans in cancer
Module
MAPK (p38) signaling
Brite
KEGG Orthology (KO) [BR:ggo00001]
 Environmental Information Processing
  Signal transduction
   04015 Rap1 signaling pathway
    101134492 (MAPK12)
   04010 MAPK signaling pathway
    101134492 (MAPK12)
   04370 VEGF signaling pathway
    101134492 (MAPK12)
   04668 TNF signaling pathway
    101134492 (MAPK12)
   04068 FoxO signaling pathway
    101134492 (MAPK12)
 Cellular Processes
  Cellular commiunity
   04550 Signaling pathways regulating pluripotency of stem cells
    101134492 (MAPK12)
 Organismal Systems
  Immune system
   04611 Platelet activation
    101134492 (MAPK12)
   04620 Toll-like receptor signaling pathway
    101134492 (MAPK12)
   04621 NOD-like receptor signaling pathway
    101134492 (MAPK12)
   04622 RIG-I-like receptor signaling pathway
    101134492 (MAPK12)
   04660 T cell receptor signaling pathway
    101134492 (MAPK12)
   04664 Fc epsilon RI signaling pathway
    101134492 (MAPK12)
   04670 Leukocyte transendothelial migration
    101134492 (MAPK12)
  Endocrine system
   04912 GnRH signaling pathway
    101134492 (MAPK12)
   04914 Progesterone-mediated oocyte maturation
    101134492 (MAPK12)
   04917 Prolactin signaling pathway
    101134492 (MAPK12)
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    101134492 (MAPK12)
  Nervous system
   04728 Dopaminergic synapse
    101134492 (MAPK12)
   04723 Retrograde endocannabinoid signaling
    101134492 (MAPK12)
   04722 Neurotrophin signaling pathway
    101134492 (MAPK12)
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    101134492 (MAPK12)
  Development
   04380 Osteoclast differentiation
    101134492 (MAPK12)
 Human Diseases
  Cancers
   05205 Proteoglycans in cancer
    101134492 (MAPK12)
  Neurodegenerative diseases
   05014 Amyotrophic lateral sclerosis (ALS)
    101134492 (MAPK12)
  Infectious diseases
   05132 Salmonella infection
    101134492 (MAPK12)
   05133 Pertussis
    101134492 (MAPK12)
   05152 Tuberculosis
    101134492 (MAPK12)
   05164 Influenza A
    101134492 (MAPK12)
   05160 Hepatitis C
    101134492 (MAPK12)
   05169 Epstein-Barr virus infection
    101134492 (MAPK12)
   05145 Toxoplasmosis
    101134492 (MAPK12)
   05140 Leishmaniasis
    101134492 (MAPK12)
   05142 Chagas disease (American trypanosomiasis)
    101134492 (MAPK12)
Enzymes [BR:ggo01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     101134492 (MAPK12)
Protein kinases [BR:ggo01001]
 Serine/threonine protein kinases: CMGC group
  MAPK family [OT]
   101134492 (MAPK12)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Position
22
AA seq 330 aa AA seqDB search
MGPDLWEDNAHTEGXXXXKKLYRPFQSELFAKRAYRELRLLKHMRHENVIGLLDVFTPDE
TLDNFTDFYLVMPFMGTDLGKLMKHEKLGEDRIQFLVYQMLKGLRYIHAAGIIHRDLKPG
NLAVNEDCELKILDFGLARQADSEMTGYVVTRWYRAPEVILNWMRYTQTVDIWSVGCIMA
EMITGKTLFKGSDHLDQLKEIMKVTGTPPAEFVQRLQSDEAKNYMKGLPEWEKKDFASIL
TNASPLAVNLLEKMLVLDAEQRVTAAEALAHPYFESLHDTEDEPQVQKYDDSFDDVDRTL
DGWKRVTYKEVLSFKPPRQLGARVSKETAL
NT seq 993 nt NT seq  +upstreamnt  +downstreamnt
atggggccagacctgtgggaggacaatgcccacacagaggggnnnnnnnnnntcaagaag
ctgtatcggcccttccagtccgagctgttcgccaagcgcgcctaccgcgagctgcgcctg
ctcaagcacatgcgccacgagaacgtgatcgggctgctggacgtattcactcctgatgag
accctggataacttcacagacttttacctggtgatgccgttcatgggcaccgacctgggc
aagctcatgaaacatgagaagctaggcgaggaccggatccagttcctcgtgtaccagatg
ctgaaggggctgaggtatatccacgctgccggcatcatccacagagacctgaagcccggc
aacctggctgtgaacgaagactgtgagctgaagatcctggactttggcctggccagacag
gcagacagtgagatgactgggtacgtggtgacccggtggtaccgggctcccgaggtcatc
ttgaattggatgcgctacacgcagacggtggacatctggtctgtgggctgcatcatggcg
gagatgatcacaggcaagacgctattcaagggcagcgaccacctggaccagctgaaggag
atcatgaaggtgacggggacgcctccggctgagtttgtgcagcggctgcagagcgatgag
gccaagaactacatgaagggcctccccgaatgggagaagaaggattttgcctccatcctg
accaatgcaagccctctggctgtgaacctcctggagaagatgctggtgctggacgcggag
cagcgggtgacggcagccgaggcgctggcccatccctacttcgagtccctgcacgacacg
gaagatgagccccaggtccagaagtatgatgactcctttgacgacgtggaccgcacactg
gatggatggaagcgtgttacttacaaagaggtgctcagcttcaagcctccccggcagctg
ggggccagggtctccaaggagacggctctgtga

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