KEGG   Gorilla gorilla gorilla (western lowland gorilla): 101135988Help
Entry
101135988         CDS       T02442                                 

Gene name
MAPK3
Definition
mitogen-activated protein kinase 3
Orthology
K04371  
mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
Organism
ggo  Gorilla gorilla gorilla (western lowland gorilla)
Pathway
MAPK signaling pathway
ErbB signaling pathway
Ras signaling pathway
Rap1 signaling pathway
cGMP-PKG signaling pathway
Chemokine signaling pathway
HIF-1 signaling pathway
FoxO signaling pathway
Oocyte meiosis
mTOR signaling pathway
PI3K-Akt signaling pathway
Adrenergic signaling in cardiomyocytes
Vascular smooth muscle contraction
Dorso-ventral axis formation
TGF-beta signaling pathway
Axon guidance
VEGF signaling pathway
Osteoclast differentiation
Focal adhesion
Adherens junction
Gap junction
Platelet activation
Toll-like receptor signaling pathway
NOD-like receptor signaling pathway
Natural killer cell mediated cytotoxicity
T cell receptor signaling pathway
B cell receptor signaling pathway
Fc epsilon RI signaling pathway
Fc gamma R-mediated phagocytosis
TNF signaling pathway
Circadian entrainment
Long-term potentiation
Neurotrophin signaling pathway
Retrograde endocannabinoid signaling
Glutamatergic synapse
Cholinergic synapse
Serotonergic synapse
Long-term depression
Regulation of actin cytoskeleton
Insulin signaling pathway
GnRH signaling pathway
Progesterone-mediated oocyte maturation
Estrogen signaling pathway
Melanogenesis
Prolactin signaling pathway
Thyroid hormone signaling pathway
Oxytocin signaling pathway
Type II diabetes mellitus
Aldosterone-regulated sodium reabsorption
Alzheimer's disease
Prion diseases
Alcoholism
Salmonella infection
Pertussis
Leishmaniasis
Chagas disease (American trypanosomiasis)
Toxoplasmosis
Tuberculosis
Hepatitis C
Hepatitis B
Influenza A
Pathways in cancer
Viral carcinogenesis
Proteoglycans in cancer
Colorectal cancer
Renal cell carcinoma
Pancreatic cancer
Endometrial cancer
Glioma
Prostate cancer
Thyroid cancer
Melanoma
Bladder cancer
Chronic myeloid leukemia
Acute myeloid leukemia
Non-small cell lung cancer
Brite
KEGG Orthology (KO) [BR:ggo00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    101135988 (MAPK3)
   04015 Rap1 signaling pathway
    101135988 (MAPK3)
   04010 MAPK signaling pathway
    101135988 (MAPK3)
   04012 ErbB signaling pathway
    101135988 (MAPK3)
   04350 TGF-beta signaling pathway
    101135988 (MAPK3)
   04370 VEGF signaling pathway
    101135988 (MAPK3)
   04668 TNF signaling pathway
    101135988 (MAPK3)
   04066 HIF-1 signaling pathway
    101135988 (MAPK3)
   04068 FoxO signaling pathway
    101135988 (MAPK3)
   04022 cGMP - PKG signaling pathway
    101135988 (MAPK3)
   04151 PI3K-Akt signaling pathway
    101135988 (MAPK3)
   04150 mTOR signaling pathway
    101135988 (MAPK3)
 Cellular Processes
  Cell motility
   04810 Regulation of actin cytoskeleton
    101135988 (MAPK3)
  Cell growth and death
   04114 Oocyte meiosis
    101135988 (MAPK3)
  Cell communication
   04510 Focal adhesion
    101135988 (MAPK3)
   04520 Adherens junction
    101135988 (MAPK3)
   04540 Gap junction
    101135988 (MAPK3)
 Organismal Systems
  Immune system
   04611 Platelet activation
    101135988 (MAPK3)
   04620 Toll-like receptor signaling pathway
    101135988 (MAPK3)
   04621 NOD-like receptor signaling pathway
    101135988 (MAPK3)
   04650 Natural killer cell mediated cytotoxicity
    101135988 (MAPK3)
   04660 T cell receptor signaling pathway
    101135988 (MAPK3)
   04662 B cell receptor signaling pathway
    101135988 (MAPK3)
   04664 Fc epsilon RI signaling pathway
    101135988 (MAPK3)
   04666 Fc gamma R-mediated phagocytosis
    101135988 (MAPK3)
   04062 Chemokine signaling pathway
    101135988 (MAPK3)
  Endocrine system
   04910 Insulin signaling pathway
    101135988 (MAPK3)
   04912 GnRH signaling pathway
    101135988 (MAPK3)
   04915 Estrogen signaling pathway
    101135988 (MAPK3)
   04914 Progesterone-mediated oocyte maturation
    101135988 (MAPK3)
   04917 Prolactin signaling pathway
    101135988 (MAPK3)
   04921 Oxytocin signaling pathway
    101135988 (MAPK3)
   04919 Thyroid hormone signaling pathway
    101135988 (MAPK3)
   04916 Melanogenesis
    101135988 (MAPK3)
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    101135988 (MAPK3)
   04270 Vascular smooth muscle contraction
    101135988 (MAPK3)
  Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    101135988 (MAPK3)
  Nervous system
   04724 Glutamatergic synapse
    101135988 (MAPK3)
   04725 Cholinergic synapse
    101135988 (MAPK3)
   04726 Serotonergic synapse
    101135988 (MAPK3)
   04720 Long-term potentiation
    101135988 (MAPK3)
   04730 Long-term depression
    101135988 (MAPK3)
   04723 Retrograde endocannabinoid signaling
    101135988 (MAPK3)
   04722 Neurotrophin signaling pathway
    101135988 (MAPK3)
  Development
   04320 Dorso-ventral axis formation
    101135988 (MAPK3)
   04360 Axon guidance
    101135988 (MAPK3)
   04380 Osteoclast differentiation
    101135988 (MAPK3)
  Environmental adaptation
   04713 Circadian entrainment
    101135988 (MAPK3)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    101135988 (MAPK3)
   05205 Proteoglycans in cancer
    101135988 (MAPK3)
   05203 Viral carcinogenesis
    101135988 (MAPK3)
   05210 Colorectal cancer
    101135988 (MAPK3)
   05212 Pancreatic cancer
    101135988 (MAPK3)
   05214 Glioma
    101135988 (MAPK3)
   05216 Thyroid cancer
    101135988 (MAPK3)
   05221 Acute myeloid leukemia
    101135988 (MAPK3)
   05220 Chronic myeloid leukemia
    101135988 (MAPK3)
   05218 Melanoma
    101135988 (MAPK3)
   05211 Renal cell carcinoma
    101135988 (MAPK3)
   05219 Bladder cancer
    101135988 (MAPK3)
   05215 Prostate cancer
    101135988 (MAPK3)
   05213 Endometrial cancer
    101135988 (MAPK3)
   05223 Non-small cell lung cancer
    101135988 (MAPK3)
  Neurodegenerative diseases
   05010 Alzheimer's disease
    101135988 (MAPK3)
   05020 Prion diseases
    101135988 (MAPK3)
  Substance dependence
   05034 Alcoholism
    101135988 (MAPK3)
  Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    101135988 (MAPK3)
  Infectious diseases
   05132 Salmonella infection
    101135988 (MAPK3)
   05133 Pertussis
    101135988 (MAPK3)
   05152 Tuberculosis
    101135988 (MAPK3)
   05164 Influenza A
    101135988 (MAPK3)
   05161 Hepatitis B
    101135988 (MAPK3)
   05160 Hepatitis C
    101135988 (MAPK3)
   05145 Toxoplasmosis
    101135988 (MAPK3)
   05140 Leishmaniasis
    101135988 (MAPK3)
   05142 Chagas disease (American trypanosomiasis)
    101135988 (MAPK3)
Enzymes [BR:ggo01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     101135988 (MAPK3)
Protein kinases [BR:ggo01001]
 Serine/threonine protein kinases: CMGC group
  MAPK family [Table]
   101135988 (MAPK3)
Exosome [BR:ggo04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   101135988 (MAPK3)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Position
16
AA seq 609 aa AA seqDB search
MPARLPQPLLPSNLQAPFSLAPGHSEPPSQSGSCPAHPTLPPSPPSPRLNSVGSRALDTV
LTPGHPPPSWPRWSLALASAERSGAPAAPTPSSVPPRAAAPAAWPRRWLGRGDSRAPPQP
AAPTRAPPTGGPRPGPPAPPRPSLTCCRERTVTPQKPEVEEEEEEEEGAGGAGDWPAEDA
LVKTMNEKQPCARLRGGRAPWGGALPGPPCAPGPPLRPPPSPAPARAPRWSPTIAQAAIP
APGSESKLLFKILFNCKNLRAVLYSKACDWTGLDRDKGDPGPRFWWAAAYIGWVALVGHA
LAASPSRGGSAYDHVRKTRVAIKKISPFEHQTYCQRTLREIQILLRFRHENVIGIRDILR
ASTLEAMRDVYIVQDLMETDLYKLLKSQQLSNDHICYFLYQILRGLKYIHSANVLHRDLK
PSNLLINTTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDI
WSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINMKARNYLQSLPSKT
KVAWAKLFPKSDSKALDLLDRMLTFNPNKRITVEEALAHPYLEQYYDPTDEVGQSPAAVG
LGAGEQGGT
NT seq 1830 nt NT seq  +upstreamnt  +downstreamnt
atgcctgctcgccttccccagcctctccttccgtctaacctgcaagcccccttctccctg
gccccaggccactctgagccaccttctcaatctggcagctgccctgctcaccccaccctg
cccccgtccccaccctccccgagactcaattccgtggggagtcgggccctcgacactgtg
ctgacccccggccacccacctccatcttggccgcggtggtccctagccctcgcctccgca
gagcgctctggggccccggcggcccccactccaagcagcgtccccccacgggctgctgcg
cccgctgcctggccccggcgctggctgggtcgcggtgacagccgcgcgcccccgcagccc
gcggctcccacgcgcgcgccgcccacaggtggccctcgccccggcccacccgcgcctccc
aggcccagcctcacctgctgccgagagaggacagtgaccccccaaaagccggaggtggag
gaggaggaggaagaggaggaaggagctggaggagccggggactggcccgctgaggatgct
cttgtcaagacaatgaatgagaagcagccgtgcgcccgcctccggggtggccgcgcccct
tggggcggagctcttccaggcccgccctgcgctcccgggcccccgctgcggccgcctccc
tccccggcccctgcccgcgcaccacgttggtccccaaccatagcgcaggctgccatcccg
gctccgggaagcgaatctaaacttctttttaaaatattattcaattgtaaaaaccttagg
gctgtactgtactcaaaggcctgcgactggacgggactagaccgagataagggtgatccc
gggcccaggttctggtgggctgccgcatacattggctgggtggctctggtaggtcacgcc
ctggccgcttcgccatcgaggggaggctcggcctatgaccacgtgcgcaagactcgcgtg
gccatcaagaagatcagccccttcgaacatcagacctactgccagcgcacgctccgggag
atccagatcctgctgcgcttccgccatgagaatgtcatcggcatccgagacattctgcgg
gcgtccaccctggaagccatgagggatgtctacattgtgcaggacctgatggagactgac
ctgtacaagttgctgaaaagccagcagctgagcaatgaccatatctgctacttcctctac
cagatcctgcggggcctcaagtacatccactccgccaacgtgctccaccgagatctaaag
ccctccaacctgctcatcaacaccacctgcgaccttaagatttgtgatttcggcctggcc
cggattgccgatcctgagcatgaccacactggcttcctgacggagtatgtggctacgcgc
tggtaccgggccccagagatcatgctgaactccaagggctataccaagtccatcgacatc
tggtctgtgggctgcattctggctgagatgctctctaaccggcccatcttccctggcaag
cactacctggatcagctcaaccacattctgggcatcctgggctccccatcccaggaggac
ctgaattgtatcatcaacatgaaggcccgaaactacctacagtctctgccctccaagacc
aaggtggcttgggccaagcttttccccaagtcagactccaaagcccttgacctgctggac
cggatgttaacctttaaccccaataaacggatcacagtggaggaagcgctggctcacccc
tacctggagcagtactatgacccgacggatgaggtgggccagtccccagcagcagtgggg
ctgggggcaggggagcaggggggcacgtag

DBGET integrated database retrieval system