KEGG   Gorilla gorilla gorilla (western lowland gorilla): 101139873
Entry
101139873         CDS       T02442                                 
Symbol
ADCY6
Name
(RefSeq) adenylate cyclase type 6
  KO
K08046  adenylate cyclase 6 [EC:4.6.1.1]
Organism
ggo  Gorilla gorilla gorilla (western lowland gorilla)
Pathway
ggo00230  Purine metabolism
ggo01100  Metabolic pathways
ggo01522  Endocrine resistance
ggo04015  Rap1 signaling pathway
ggo04022  cGMP-PKG signaling pathway
ggo04024  cAMP signaling pathway
ggo04062  Chemokine signaling pathway
ggo04072  Phospholipase D signaling pathway
ggo04114  Oocyte meiosis
ggo04211  Longevity regulating pathway
ggo04213  Longevity regulating pathway - multiple species
ggo04261  Adrenergic signaling in cardiomyocytes
ggo04270  Vascular smooth muscle contraction
ggo04371  Apelin signaling pathway
ggo04540  Gap junction
ggo04611  Platelet activation
ggo04713  Circadian entrainment
ggo04714  Thermogenesis
ggo04723  Retrograde endocannabinoid signaling
ggo04724  Glutamatergic synapse
ggo04725  Cholinergic synapse
ggo04727  GABAergic synapse
ggo04742  Taste transduction
ggo04750  Inflammatory mediator regulation of TRP channels
ggo04911  Insulin secretion
ggo04912  GnRH signaling pathway
ggo04913  Ovarian steroidogenesis
ggo04914  Progesterone-mediated oocyte maturation
ggo04915  Estrogen signaling pathway
ggo04916  Melanogenesis
ggo04918  Thyroid hormone synthesis
ggo04921  Oxytocin signaling pathway
ggo04923  Regulation of lipolysis in adipocytes
ggo04924  Renin secretion
ggo04925  Aldosterone synthesis and secretion
ggo04926  Relaxin signaling pathway
ggo04927  Cortisol synthesis and secretion
ggo04928  Parathyroid hormone synthesis, secretion and action
ggo04934  Cushing syndrome
ggo04935  Growth hormone synthesis, secretion and action
ggo04961  Endocrine and other factor-regulated calcium reabsorption
ggo04962  Vasopressin-regulated water reabsorption
ggo04970  Salivary secretion
ggo04971  Gastric acid secretion
ggo04972  Pancreatic secretion
ggo04976  Bile secretion
ggo05032  Morphine addiction
ggo05163  Human cytomegalovirus infection
ggo05166  Human T-cell leukemia virus 1 infection
ggo05200  Pathways in cancer
ggo05207  Chemical carcinogenesis - receptor activation
ggo05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:ggo00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    101139873 (ADCY6)
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    101139873 (ADCY6)
   04371 Apelin signaling pathway
    101139873 (ADCY6)
   04072 Phospholipase D signaling pathway
    101139873 (ADCY6)
   04024 cAMP signaling pathway
    101139873 (ADCY6)
   04022 cGMP-PKG signaling pathway
    101139873 (ADCY6)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    101139873 (ADCY6)
  09144 Cellular community - eukaryotes
   04540 Gap junction
    101139873 (ADCY6)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    101139873 (ADCY6)
   04062 Chemokine signaling pathway
    101139873 (ADCY6)
  09152 Endocrine system
   04911 Insulin secretion
    101139873 (ADCY6)
   04923 Regulation of lipolysis in adipocytes
    101139873 (ADCY6)
   04912 GnRH signaling pathway
    101139873 (ADCY6)
   04913 Ovarian steroidogenesis
    101139873 (ADCY6)
   04915 Estrogen signaling pathway
    101139873 (ADCY6)
   04914 Progesterone-mediated oocyte maturation
    101139873 (ADCY6)
   04921 Oxytocin signaling pathway
    101139873 (ADCY6)
   04926 Relaxin signaling pathway
    101139873 (ADCY6)
   04935 Growth hormone synthesis, secretion and action
    101139873 (ADCY6)
   04918 Thyroid hormone synthesis
    101139873 (ADCY6)
   04928 Parathyroid hormone synthesis, secretion and action
    101139873 (ADCY6)
   04916 Melanogenesis
    101139873 (ADCY6)
   04924 Renin secretion
    101139873 (ADCY6)
   04925 Aldosterone synthesis and secretion
    101139873 (ADCY6)
   04927 Cortisol synthesis and secretion
    101139873 (ADCY6)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    101139873 (ADCY6)
   04270 Vascular smooth muscle contraction
    101139873 (ADCY6)
  09154 Digestive system
   04970 Salivary secretion
    101139873 (ADCY6)
   04971 Gastric acid secretion
    101139873 (ADCY6)
   04972 Pancreatic secretion
    101139873 (ADCY6)
   04976 Bile secretion
    101139873 (ADCY6)
  09155 Excretory system
   04962 Vasopressin-regulated water reabsorption
    101139873 (ADCY6)
   04961 Endocrine and other factor-regulated calcium reabsorption
    101139873 (ADCY6)
  09156 Nervous system
   04724 Glutamatergic synapse
    101139873 (ADCY6)
   04727 GABAergic synapse
    101139873 (ADCY6)
   04725 Cholinergic synapse
    101139873 (ADCY6)
   04723 Retrograde endocannabinoid signaling
    101139873 (ADCY6)
  09157 Sensory system
   04742 Taste transduction
    101139873 (ADCY6)
   04750 Inflammatory mediator regulation of TRP channels
    101139873 (ADCY6)
  09149 Aging
   04211 Longevity regulating pathway
    101139873 (ADCY6)
   04213 Longevity regulating pathway - multiple species
    101139873 (ADCY6)
  09159 Environmental adaptation
   04713 Circadian entrainment
    101139873 (ADCY6)
   04714 Thermogenesis
    101139873 (ADCY6)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    101139873 (ADCY6)
   05207 Chemical carcinogenesis - receptor activation
    101139873 (ADCY6)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    101139873 (ADCY6)
   05163 Human cytomegalovirus infection
    101139873 (ADCY6)
  09165 Substance dependence
   05032 Morphine addiction
    101139873 (ADCY6)
  09166 Cardiovascular disease
   05414 Dilated cardiomyopathy
    101139873 (ADCY6)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    101139873 (ADCY6)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    101139873 (ADCY6)
Enzymes [BR:ggo01000]
 4. Lyases
  4.6  Phosphorus-oxygen lyases
   4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)
    4.6.1.1  adenylate cyclase
     101139873 (ADCY6)
SSDB
Motif
Pfam: AC_N Guanylate_cyc Adcy_cons_dom HNOBA TBK1_ULD GBR2_CC
Other DBs
NCBI-GeneID: 101139873
NCBI-ProteinID: XP_004053103
Ensembl: ENSGGOG00000002316
UniProt: G3QIR6
Position
12:36177914..36201552
AA seq 1168 aa
MSWFSGLLVPKVDERKTAWGERNGQKRSRRRGTRAGGFCTPRYMSCLRDAEPPSPTSAGP
PRCPWQDDAFIRRGGPGKGKELGLRAVALGFEDTEVTTTAGGTAEVAPDAVPRSGRSCWR
RLVQVFQSKQFRSAKLERLYQRYFFQMNQSSLTLLMAVLVLLTAVLLAFHAAPARPQPAY
VALLACAAALFVGLMVVCNRHSFRQDSMWVVSYVVLGILAAVQVGGALAADPRSPSAGLW
CPVFFVYIAYTLLPIRMRAAVLSGLGLSTLHLILAWQLNRGDAFLWKQLGANVLLFLCTN
VIGICTHYPAEVSQRQAFQETRGYIQARLHLQHENRQQERLLLSVLPQHVAMEMKEDINT
KKEDMMFHKIYIQKHDNVSILFADIEGFTSLASQCTAQELVMTLNELFARFDKLAAENHC
LRIKILGDCYYCVSGLPEARADHAHCCVEMGVDMIEAISLVREVTGVNVNMRVGIHSGRV
HCGVLGLRKWQFDVWSNDVTLANHMEAGGRAGRIHITRATLQYLNGDYEVEPGRGGERNA
YLKEQHIETFLILGASQKRKEEKAMLAKLQRTRANSMEGLMPRWVPDRAFSRTKDSKAFR
QMGIDDSSKDNRGTQDALNPEDEVDEFLSRAIDARSIDQLRKDHVRRFLLTFQREDLEKK
YSRKVDPRFGAYVACALLVFCFICFIQLLIFPHSTLMLGIYASIFLLLLITVLICAVYSC
GSLFPKALQRLSRSIVRSRAHSTAVGIFSVLLVFTSAIANMFTCNHTPIRTCAARMLNLT
PADITACHLQQLNYSLGLDAPLCEGTMPTCSFPEYFIGNMLLSLLASSVFLHISSIGKLA
MIFVLGLIYLVLLLLGPPATIFDNYDLLLGVHGLASSNETFDGLDCPAAGRVALKYMTPV
ILLVFALALYLHAQQVESTARLDFLWKLQATGEKEEMEELQAYNRRLLHNILPKDVAAHF
LARERRNDELYYQSCECVAVMFASIANFSEFYVELEANNEGVECLRLLNEIIADFDEIIS
EERFRQLEKIKTIGSTYMAASGLNASTYDQVGRSHITALADYAMRLMEQMKHINEHSFNN
FQMKIGLNMGPVVAGVIGARKPQYDIWGNTVNVSSRMDSTGVPDRIQVTTDLYQVLAAKG
YQLECRGVVKVKGKGEMTTYFLNGGPSS
NT seq 3507 nt   +upstreamnt  +downstreamnt
atgtcatggtttagtggcctcctggtccctaaagtggatgaacggaaaacagcctggggt
gaacgcaatgggcagaagcgttcgcggcgccgtggcactcgggcaggtggcttctgcacg
ccccgctatatgagctgcctccgggatgcagagccacccagccccacctctgcgggcccc
cctcggtgtccctggcaggatgacgccttcatccggaggggcggcccaggcaagggcaag
gagctggggctgcgggcagtggccctgggcttcgaggataccgaggtgacaacgacagcg
ggcgggacggctgaggtggcgcccgacgcggtgcccaggagtgggcgatcctgctggcgc
cgtctggtgcaggtgttccagtcgaagcagttccgttcggccaagctggagcgcctgtac
cagcggtacttcttccagatgaaccagagcagcctgacgctgctgatggcggtgctggtg
ctgctcacggcggtgctgctggctttccacgccgcacctgcccgccctcagcctgcctat
gtggcactgttggcctgtgccgccgccctgttcgtggggctcatggtggtgtgtaaccgg
catagcttccgccaggactccatgtgggtggtgagctacgtggtgctgggcatcctggcg
gcagtgcaggtcgggggcgccctcgcagcagacccgcgcagcccctctgcgggcctctgg
tgccctgtgttctttgtctacatcgcctacacgctcctccccatccgcatgcgggctgcc
gtcctcagcggcctgggcctctccaccttgcatttgatcttggcctggcaacttaaccgt
ggtgatgccttcctctggaagcagctcggtgccaatgtgctgctgttcctctgcaccaat
gtcattggcatctgcacacactatccagcagaggtgtctcagcgccaggcctttcaggag
acccgcggttacatccaggcccggctccacctgcagcatgagaatcggcagcaggagcgg
ctgctgctgtcggtattgccccagcacgttgccatggagatgaaagaagacatcaacaca
aaaaaagaagacatgatgttccacaagatctacatacagaagcatgacaatgtcagcatc
ctgtttgcagacattgagggcttcaccagcctggcatcccagtgcaccgcccaggagctg
gtcatgaccctgaatgagctctttgcccggtttgacaagctggctgcggagaatcactgc
ctgaggatcaagatcttgggggactgttactactgtgtgtcagggctgccagaggccagg
gccgaccatgcccactgctgtgtggagatgggggtagacatgatcgaggccatctcgctg
gtacgtgaggtgacaggtgtgaatgtgaacatgcgcgtgggcatccacagcgggcgagtg
cactgcggcgtccttggcttgcggaaatggcagttcgatgtgtggtccaatgatgtgacc
ctggccaaccacatggaggcaggaggccgggctggccgcatccacatcactcgggcaaca
ctgcagtacctgaatggggactacgaggtggagccaggccgtggtggcgagcgcaacgca
tacctcaaggagcagcacattgagactttcctcatcctgggcgccagccagaaacggaaa
gaggagaaggccatgctggccaagctgcagcggactcgggccaactccatggaagggctg
atgccgcgctgggtgcctgatcgtgccttctcccggaccaaggactccaaggccttccgc
cagatgggcattgatgattccagcaaagacaaccggggcacccaagatgccctgaaccct
gaggatgaggtggatgagttcctgagccgtgccattgatgcccgcagcattgatcagctg
cggaaggaccatgtgcgccggtttctgctcaccttccagagagaggatcttgagaagaag
tactcccggaaggtggatccccgcttcggagcctacgttgcctgtgccctgttggtcttc
tgcttcatctgcttcatccagcttctcatcttcccacactccaccctgatgcttgggatc
tatgccagcatcttcctgctgctgctgatcaccgtgctgatctgtgccgtgtactcctgt
ggttctctgttccctaaggccctgcaacgtctgtcccgcagcattgtccgctcacgggca
catagcaccgcagttggcatcttttccgtcctgcttgtgtttacttctgccattgccaac
atgttcacctgtaaccacacccccatacggacctgtgcagcccggatgctgaatttaaca
cctgctgacatcactgcctgccacctgcagcagctcaattactctctgggcctggatgct
cccctgtgtgagggcaccatgcccacctgcagctttcctgagtacttcatcgggaacatg
ctgctgagtctcttggccagctctgtcttcctgcacatcagcagcatcgggaagttggcc
atgatctttgtcttggggctcatctatttggtgctgcttctgctgggtcccccagccacc
atctttgacaactatgacctactgcttggcgtccatggcttggcttcttccaatgagacc
tttgatgggctggactgtccagctgcagggagggtggccctcaaatatatgacccctgtg
attctgctggtgtttgcgctggcgctgtatctgcatgctcagcaggtggagtcgactgcc
cgcctcgacttcctctggaaactacaggcaacaggggagaaggaggagatggaggagcta
caggcatacaaccggaggctgctgcataacattctgcccaaggacgtggcggcccacttc
ctggcccgggagcgccgcaatgatgaactctactatcagtcgtgtgagtgcgtggctgtt
atgtttgcctccattgccaacttctctgagttctatgtggagctggaggcaaacaatgag
ggtgtcgagtgcctgcggctgctcaacgagatcatcgctgactttgatgagattatcagc
gaggagcggttccggcagctggaaaagatcaagacgattggtagcacctacatggctgcc
tcagggctgaacgccagcacctacgatcaggtgggccgctctcacatcactgccctggct
gactacgccatgcggctcatggagcagatgaagcacatcaatgagcactccttcaacaat
ttccagatgaagattgggctgaacatgggcccagtcgtggcaggtgtcatcggggctcgg
aagccacagtatgacatctgggggaacacagtgaatgtctctagtcgtatggacagcacg
ggggtccccgaccgaatccaggtgaccacggacctgtaccaggttctagctgccaagggc
taccagctggagtgtcgaggggtggtcaaggtgaagggcaagggggagatgaccacctac
ttcctcaatgggggccccagcagttaa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (52)   
   KEGG PATHWAY (52)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (5)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (4)   
   UniProt (1)   
   RefSeq(pep) (3)   
DNA sequence (3)   
   RefSeq(nuc) (3)   
Protein domain (6)   
   Pfam (6)   
All databases (81)   

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