KEGG   Gorilla gorilla gorilla (western lowland gorilla): 101144696Help
Entry
101144696         CDS       T02442                                 

Gene name
INSR
Definition
(RefSeq) insulin receptor
  KO
K04527  
insulin receptor [EC:2.7.10.1]
Organism
ggo  Gorilla gorilla gorilla (western lowland gorilla)
Pathway
MAPK signaling pathway
Ras signaling pathway
Rap1 signaling pathway
cGMP-PKG signaling pathway
HIF-1 signaling pathway
FoxO signaling pathway
Phospholipase D signaling pathway
mTOR signaling pathway
PI3K-Akt signaling pathway
AMPK signaling pathway
Longevity regulating pathway
Longevity regulating pathway - multiple species
Adherens junction
Insulin signaling pathway
Ovarian steroidogenesis
Regulation of lipolysis in adipocytes
Type II diabetes mellitus
Insulin resistance
Non-alcoholic fatty liver disease (NAFLD)
Aldosterone-regulated sodium reabsorption
Module
PI3K-Akt signaling
Brite
KEGG Orthology (KO) [BR:ggo00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    101144696 (INSR)
   04015 Rap1 signaling pathway
    101144696 (INSR)
   04010 MAPK signaling pathway
    101144696 (INSR)
   04066 HIF-1 signaling pathway
    101144696 (INSR)
   04068 FoxO signaling pathway
    101144696 (INSR)
   04072 Phospholipase D signaling pathway
    101144696 (INSR)
   04022 cGMP - PKG signaling pathway
    101144696 (INSR)
   04151 PI3K-Akt signaling pathway
    101144696 (INSR)
   04152 AMPK signaling pathway
    101144696 (INSR)
   04150 mTOR signaling pathway
    101144696 (INSR)
 Cellular Processes
  Cellular community - eukaryotes
   04520 Adherens junction
    101144696 (INSR)
 Organismal Systems
  Endocrine system
   04910 Insulin signaling pathway
    101144696 (INSR)
   04923 Regulation of lipolysis in adipocyte
    101144696 (INSR)
   04913 Ovarian Steroidogenesis
    101144696 (INSR)
  Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    101144696 (INSR)
  Aging
   04211 Longevity regulating pathway - mammal
    101144696 (INSR)
   04213 Longevity regulating pathway - multiple species
    101144696 (INSR)
 Human Diseases
  Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    101144696 (INSR)
   04932 Non-alcoholic fatty liver disease (NAFLD)
    101144696 (INSR)
   04931 Insulin resistance
    101144696 (INSR)
Enzymes [BR:ggo01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     101144696 (INSR)
Protein kinases [BR:ggo01001]
 Tyrosine protein kinases
  InsR family [OT]
   101144696 (INSR)
Enzyme-linked receptors [BR:ggo01020]
 Receptor tyrosine kinases
  RTK class II (Insulin receptor family)
   101144696 (INSR)
Cytokine receptors [BR:ggo04050]
 Receptor tyrosine kinase
  RTK class II (Insulin receptor family)
   101144696 (INSR)
CD molecules [BR:ggo04090]
 Proteins
  101144696 (INSR)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GeneID: 
NCBI-ProteinID: 
Ensembl: 
Position
19
AA seq 1395 aa AA seqDB search
MGTLQRKLLIPAGCRVYRARDENTGPRFRVHEAGSAPDPSDASTMRLLTCLAFCSFSLLV
CPGMDIRNNLTRLHELENCSVIEGHLQILLMFKTRPEDFRDLSFPKLIMITDYLLLFRVY
GLESLKDLFPNLTVIRGSRLFFNYALVIFEMVHLKELGLYNLMNITRGSVRIEKNNELCY
LATIDWSRILDSVEDNYIVLNKDDNEECGDICPGTAKGKTNCPATVINGQFVERCWTHSH
CQKVCPTICKSHGCTAEGLCCHSECLGNCSQPDDPTKCVACRNFYLDGRCVETCPPPYYH
FQDWRCVNFSFCQDLHHKCKNSRRQGCHQYVIHNNKCIPECPSGYTMNSSNGFPRPMDGI
QTPHREGSASSHSHFIPKLTGYSLLSLDNLAAELEANLGLIEEISGYLKIRRSYALVSLS
FFRKLRLIRGETLEIGNYSFYALDNQNLRQLWDWSKHNLTITQGKLFFHYNPKLCLSEIH
KMEEVSGTKGRQERNDIALKTNGDQASCENELLKFSYIRTSFDKILLRWEPYWPPDFRDL
LGFMLFYKEAPYQNVTEFDGQDACGSNSWTVVDIDPPLRSNDPKSQNHPGWLMRGLKPWT
QYAIFVKTLVTFSDERRTYGAKSDIIYVQTDATNPSVPLDPISVSNSSSQIILKWKPPSD
PNGNITHYLVFWERQAEDSELFELDYCLKGLKLPSRTWSPPFESEDSQKHNQSEYEDSAG
ECCSCPKTDSQILKELEESSFRKTFEDYLHNVVFVPRKTSSGTGAEDPRPSRKRRSLGDV
GNVTVAVPTVAAFPNTSSTSVPTSPEEHRPFEKVVNKESLVISGLRHFTGYRIELQACNQ
DTPEERCSVAAYVSARTMPEAKADDIVGPVTHEIFENNVVHLMWQEPKEPNGLIVLYEVS
YRRYGDEELHLCVSRKHFALERGCRLRGLSPGNYSVRVRATSLAGNGSWTEPTYFYVTDY
LDVPSNIAKIIIGPLIFVFLFSVVIGSIYLFLRKRQPDGPLGPLYASSNPEYLSASDVFP
CSVYVPDEWEVPREKITLLRELGQGSFGMVYEGNARDIIKGEAETRVAVKTVNESASLRE
RIEFLNEASVMKGFTCHHVVRLLGVVSKGQPTLVVMELMAHGDLKSYLRSLRPEAENNPG
RPPPTLQEMIQMAAEIADGMAYLNAKKFVHRDLAARNCMVAHDFTVKIGDFGMTRDIYET
DYYRKGGKGLLPVRWMAPESLKDGVFTTSSDMWSFGVVLWEITSLAEQPYQGLSNEQVLK
FVMDGGYLDQPDNCPERVTDLMRMCWQFNPKMRPTFLEIVNLLKDDLHPSFPEVSFFHSE
ENKAPESEELEMEFEDMENVPLDRSSHCQREEAGGRDGGSSLGFKRSYEEHIPYTHMNGG
KKNGRILTLPRSNPS
NT seq 4188 nt NT seq  +upstreamnt  +downstreamnt
atgggtactttacagagaaagctactcatcccggctggctgcagagtttacagggcccga
gatgaaaacacagggcccaggtttcgtgtccatgaagccggctctgcccctgatccttct
gatgcatccaccatgcgtctgctcacctgtcttgctttctgttcattttctcttctagtg
tgtcccggcatggatatccggaacaacctcactaggttgcatgagctggagaattgctct
gtcatcgaaggacacttgcagatactcttgatgttcaaaacgaggcccgaagatttccga
gacctcagtttccccaaactcataatgatcactgattacttgctgctcttccgggtctat
gggctcgagagcctgaaggacctgttccccaacctcacggtcatccggggatcacgactg
ttctttaactacgcgctggtcatcttcgagatggttcacctcaaggaactcggcctctac
aacctgatgaacatcacccggggttctgtccgcatcgagaagaacaatgagctctgttac
ttggccactatcgactggtcccgtatcctggattccgtggaggataattacatcgtgttg
aacaaagatgacaacgaggagtgtggagacatctgtccgggtaccgcgaagggcaagacc
aactgccccgccaccgtcatcaatgggcagtttgtcgaacggtgttggactcatagtcac
tgccagaaagtttgcccgaccatctgtaagtcacacggctgcaccgccgaaggcctctgt
tgccacagcgagtgcctgggcaactgttctcagcccgacgaccccaccaagtgcgtggcc
tgccgcaacttctacctggacggcaggtgtgtggagacctgcccgcccccgtactaccac
ttccaggactggcgctgtgtgaacttcagcttctgccaggacctgcaccacaaatgcaag
aactcgcggaggcagggctgccaccagtacgtcattcacaacaacaagtgcatccctgag
tgtccctccgggtacacgatgaattccagcaatggcttcccaagaccaatggacggaatc
caaactccccatcgggaaggctcggccagttctcattctcatttcattccgaaactcact
ggatattctctcctttccttagacaatctggcagctgagctagaagccaacctcggcctc
attgaagaaatttcagggtatctaaaaatccgccgatcctacgctctggtgtcactttcc
ttcttccggaagttacgtctgattcgaggagagaccttggaaatcgggaactactccttc
tatgccttggacaaccagaacctaaggcagctctgggattggagcaaacacaacctcacc
atcactcaggggaaactcttcttccactataaccccaaactctgcttgtcagaaatccac
aagatggaagaagtttcaggaaccaaggggcgccaggagagaaacgacattgccctgaag
accaatggcgaccaggcatcctgtgaaaatgagttacttaaattttcttacattcggaca
tcttttgacaagatcttgctgagatgggagccgtactggccccccgacttccgagacctc
ttggggttcatgctgttctacaaagaggccccttatcagaatgtgacggagttcgacggg
caggatgcatgtggttccaacagttggacggtggtagacattgacccacccctgagatcc
aatgaccccaaatcacagaaccacccagggtggctgatgcggggtctcaagccctggacc
cagtatgccatcttcgtgaagaccctggtcaccttttcggatgaacgccggacctatggg
gccaagagtgacatcatttatgtccagacagatgccaccaacccctccgtgcccctggat
ccaatctcagtgtctaactcatcatcccagattattttgaagtggaaacccccctccgac
cccaatggcaacatcacccactacctggttttctgggagaggcaggcggaagacagtgag
ctgttcgagctggattattgcctcaaagggctgaagctgccctcgaggacctggtctcca
ccattcgagtctgaagattctcagaagcacaaccagagtgagtatgaggattcggccggc
gaatgctgctcctgtccaaagacagactctcagatcctgaaggagctggaggagtcctcg
tttaggaagacgtttgaggattacctgcacaacgtggttttcgtccccagaaaaacctct
tcaggcactggtgccgaggaccctaggccatctcggaaacgcaggtcccttggcgatgtt
gggaatgtgacggtggccgtgcccacggtggcagctttccccaacacttcctcaaccagc
gtgcccacgagtccagaggagcacaggccttttgagaaggtggtgaacaaggagtcgctg
gtcatctccggcttgcgacacttcacgggctatcgcatcgagctgcaggcttgcaaccag
gacacccctgaggaacggtgcagtgtggcagcctacgtcagtgccaggaccatgcctgaa
gccaaggctgatgacattgtcggccctgtgacgcatgaaatctttgagaacaacgtcgtc
cacttgatgtggcaggagccgaaggagcccaatggtctgatcgtgctgtatgaagtgagt
tatcggcgatatggtgatgaggagctgcatctctgcgtctcccgcaagcacttcgctctg
gaacggggctgcaggctgcgtggactgtcaccggggaactacagcgtgcgagtccgggcc
acctcccttgcgggcaacggctcttggacggaacccacctatttctacgtgacagactat
ttagatgtcccgtcaaatattgcaaaaattatcattggccccctcatctttgtctttctc
ttcagtgttgtgattggaagtatttatctattcctgagaaagaggcagccagatgggccg
ctgggaccgctttatgcttcttcaaaccctgagtatctcagtgccagtgatgtgtttcca
tgctctgtgtacgtgccggacgagtgggaggtgcctcgagagaagatcaccctccttcga
gagctggggcagggatccttcggcatggtgtatgagggcaatgccagggacatcatcaag
ggtgaggcagagacccgcgtggcggtgaagacggtcaacgagtcagccagtctccgagag
cggattgagttcctcaatgaggcctcggtcatgaagggcttcacctgccatcacgtggtg
cgcctcctgggagtggtgtccaagggccagcccacgctggtggtgatggagctgatggct
cacggagacctgaagagctacctccgttctctgcggccagaggctgagaataatcccggc
cgccctccccctacccttcaagagatgattcagatggcggcagagattgctgacgggatg
gcctacctgaacgccaagaagtttgtgcatcgggacctggcagcgagaaactgcatggtc
gcccatgattttactgtcaaaattggagactttggaatgaccagagacatctatgaaacg
gattactaccggaaagggggcaagggtctgctccctgtacggtggatggcgccggagtcc
ctgaaggatggggtcttcaccacttcttctgacatgtggtcctttggcgtggtcctttgg
gaaatcaccagcttggcagaacagccttaccaaggcctgtctaatgaacaggtgttgaaa
tttgtcatggatggagggtatctggatcaacccgacaactgtccagagagagtcactgac
ctcatgcgcatgtgctggcaattcaaccccaagatgaggccaaccttcctggagattgtc
aacctgctcaaggacgacctgcaccccagctttccagaggtgtcgttcttccacagcgag
gagaacaaggctcccgagagtgaggagctggagatggagtttgaggacatggagaatgtg
cccctggaccgctcctcgcactgtcagagggaggaggcggggggccgggatggagggtcc
tcgctaggtttcaagcggagctacgaggaacacatcccttacacacacatgaacggaggc
aagaaaaacgggcggattctgaccttgcctcggtccaatccttcctaa

DBGET integrated database retrieval system