KEGG   Gorilla gorilla gorilla (western lowland gorilla): 101146434Help
Entry
101146434         CDS       T02442                                 

Gene name
PIK3CD
Definition
phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
Orthology
K00922  
phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
Organism
ggo  Gorilla gorilla gorilla (western lowland gorilla)
Pathway
Inositol phosphate metabolism
ErbB signaling pathway
Ras signaling pathway
Rap1 signaling pathway
cGMP-PKG signaling pathway
cAMP signaling pathway
Chemokine signaling pathway
HIF-1 signaling pathway
FoxO signaling pathway
Phosphatidylinositol signaling system
mTOR signaling pathway
PI3K-Akt signaling pathway
AMPK signaling pathway
Apoptosis
Adrenergic signaling in cardiomyocytes
VEGF signaling pathway
Osteoclast differentiation
Focal adhesion
Platelet activation
Toll-like receptor signaling pathway
Jak-STAT signaling pathway
Natural killer cell mediated cytotoxicity
T cell receptor signaling pathway
B cell receptor signaling pathway
Fc epsilon RI signaling pathway
Fc gamma R-mediated phagocytosis
TNF signaling pathway
Leukocyte transendothelial migration
Neurotrophin signaling pathway
Cholinergic synapse
Inflammatory mediator regulation of TRP channels
Regulation of actin cytoskeleton
Insulin signaling pathway
Progesterone-mediated oocyte maturation
Estrogen signaling pathway
Prolactin signaling pathway
Thyroid hormone signaling pathway
Oxytocin signaling pathway
Type II diabetes mellitus
Non-alcoholic fatty liver disease (NAFLD)
Aldosterone-regulated sodium reabsorption
Carbohydrate digestion and absorption
Bacterial invasion of epithelial cells
Chagas disease (American trypanosomiasis)
Toxoplasmosis
Amoebiasis
Hepatitis C
Hepatitis B
Measles
Influenza A
HTLV-I infection
Epstein-Barr virus infection
Pathways in cancer
Viral carcinogenesis
Proteoglycans in cancer
Colorectal cancer
Renal cell carcinoma
Pancreatic cancer
Endometrial cancer
Glioma
Prostate cancer
Melanoma
Chronic myeloid leukemia
Acute myeloid leukemia
Small cell lung cancer
Non-small cell lung cancer
Brite
KEGG Orthology (KO) [BR:ggo00001]
 Metabolism
  Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    101146434 (PIK3CD)
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    101146434 (PIK3CD)
   04015 Rap1 signaling pathway
    101146434 (PIK3CD)
   04012 ErbB signaling pathway
    101146434 (PIK3CD)
   04370 VEGF signaling pathway
    101146434 (PIK3CD)
   04630 Jak-STAT signaling pathway
    101146434 (PIK3CD)
   04668 TNF signaling pathway
    101146434 (PIK3CD)
   04066 HIF-1 signaling pathway
    101146434 (PIK3CD)
   04068 FoxO signaling pathway
    101146434 (PIK3CD)
   04070 Phosphatidylinositol signaling system
    101146434 (PIK3CD)
   04024 cAMP signaling pathway
    101146434 (PIK3CD)
   04022 cGMP - PKG signaling pathway
    101146434 (PIK3CD)
   04151 PI3K-Akt signaling pathway
    101146434 (PIK3CD)
   04152 AMPK signaling pathway
    101146434 (PIK3CD)
   04150 mTOR signaling pathway
    101146434 (PIK3CD)
 Cellular Processes
  Cell motility
   04810 Regulation of actin cytoskeleton
    101146434 (PIK3CD)
  Cell growth and death
   04210 Apoptosis
    101146434 (PIK3CD)
  Cell communication
   04510 Focal adhesion
    101146434 (PIK3CD)
 Organismal Systems
  Immune system
   04611 Platelet activation
    101146434 (PIK3CD)
   04620 Toll-like receptor signaling pathway
    101146434 (PIK3CD)
   04650 Natural killer cell mediated cytotoxicity
    101146434 (PIK3CD)
   04660 T cell receptor signaling pathway
    101146434 (PIK3CD)
   04662 B cell receptor signaling pathway
    101146434 (PIK3CD)
   04664 Fc epsilon RI signaling pathway
    101146434 (PIK3CD)
   04666 Fc gamma R-mediated phagocytosis
    101146434 (PIK3CD)
   04670 Leukocyte transendothelial migration
    101146434 (PIK3CD)
   04062 Chemokine signaling pathway
    101146434 (PIK3CD)
  Endocrine system
   04910 Insulin signaling pathway
    101146434 (PIK3CD)
   04915 Estrogen signaling pathway
    101146434 (PIK3CD)
   04914 Progesterone-mediated oocyte maturation
    101146434 (PIK3CD)
   04917 Prolactin signaling pathway
    101146434 (PIK3CD)
   04921 Oxytocin signaling pathway
    101146434 (PIK3CD)
   04919 Thyroid hormone signaling pathway
    101146434 (PIK3CD)
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    101146434 (PIK3CD)
  Digestive system
   04973 Carbohydrate digestion and absorption
    101146434 (PIK3CD)
  Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    101146434 (PIK3CD)
  Nervous system
   04725 Cholinergic synapse
    101146434 (PIK3CD)
   04722 Neurotrophin signaling pathway
    101146434 (PIK3CD)
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    101146434 (PIK3CD)
  Development
   04380 Osteoclast differentiation
    101146434 (PIK3CD)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    101146434 (PIK3CD)
   05205 Proteoglycans in cancer
    101146434 (PIK3CD)
   05203 Viral carcinogenesis
    101146434 (PIK3CD)
   05210 Colorectal cancer
    101146434 (PIK3CD)
   05212 Pancreatic cancer
    101146434 (PIK3CD)
   05214 Glioma
    101146434 (PIK3CD)
   05221 Acute myeloid leukemia
    101146434 (PIK3CD)
   05220 Chronic myeloid leukemia
    101146434 (PIK3CD)
   05218 Melanoma
    101146434 (PIK3CD)
   05211 Renal cell carcinoma
    101146434 (PIK3CD)
   05215 Prostate cancer
    101146434 (PIK3CD)
   05213 Endometrial cancer
    101146434 (PIK3CD)
   05222 Small cell lung cancer
    101146434 (PIK3CD)
   05223 Non-small cell lung cancer
    101146434 (PIK3CD)
  Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    101146434 (PIK3CD)
   04932 Non-alcoholic fatty liver disease (NAFLD)
    101146434 (PIK3CD)
  Infectious diseases
   05100 Bacterial invasion of epithelial cells
    101146434 (PIK3CD)
   05166 HTLV-I infection
    101146434 (PIK3CD)
   05162 Measles
    101146434 (PIK3CD)
   05164 Influenza A
    101146434 (PIK3CD)
   05161 Hepatitis B
    101146434 (PIK3CD)
   05160 Hepatitis C
    101146434 (PIK3CD)
   05169 Epstein-Barr virus infection
    101146434 (PIK3CD)
   05146 Amoebiasis
    101146434 (PIK3CD)
   05145 Toxoplasmosis
    101146434 (PIK3CD)
   05142 Chagas disease (American trypanosomiasis)
    101146434 (PIK3CD)
Enzymes [BR:ggo01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.153  phosphatidylinositol-4,5-bisphosphate 3-kinase
     101146434 (PIK3CD)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Position
1
AA seq 1044 aa AA seqDB search
MPPGVDCPMEFWTKEENQSVVVDFLLPTGVYLNFPVSRNANLSTIKQLLWHRAQYEPLFH
MLSGPEAYVFTCINQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLCDPEVNDFRAKMCQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARTWGP
GTLRLPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGRHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
AKPPPIPAKKPSSVSLWSLEQPFRIELIQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVSVCSEPVWKQRLEFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNPTGTVRSNPNTDSAAALLICLPEVAP
HPVYYPALEKILELGRHSECVHVTEEEQLQLREILERRGSGELYEHEKDLVWKLRHEVQE
HFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDCHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSV
ALRFGLILEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKLSSQKTPKPQTKELMHLCMR
QEAYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWIMYSNEEAGSGSSVGIIFKN
GDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLRSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
ERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
NT seq 3135 nt NT seq  +upstreamnt  +downstreamnt
atgccccctggggtggactgccccatggaattctggaccaaggaggagaatcagagcgtc
gtggttgacttcctgctgcccacaggggtctacctgaacttccctgtgtcccgcaatgcc
aacctcagcaccatcaagcagctgctgtggcaccgcgcccagtatgagccgctcttccac
atgctcagtggccccgaggcctatgtgttcacctgcatcaaccagacagcggagcagcaa
gagttggaggacgagcaacggcgtctgtgtgacgtgcagcccttcctgcccgtcctgcgc
ctggtggcccgtgagggcgaccgcgtgaagaagctcatcaactcacagatcagcctcctc
atcggcaaaggcctccacgagtttgactccttgtgcgacccagaagtgaacgactttcgc
gccaagatgtgccaattctgcgaggaggcggccgcccgccggcagcagctgggctgggag
gcctggctgcagtacagtttccccctgcagctggagccctcagctcgaacctgggggcct
ggcaccctgcggctcccgaaccgggcccttctggtcaacgttaagtttgagggcagcgag
gaaagcttcaccttccaggtgtccaccaaggatgtgccgctggcgctgatggcctgtgcc
ctgcggaagaaggccacggtgttccggcagccgctggtggagcagccagaagactacacg
ctgcaggtgaacggcaggcatgagtacctgtatggcagctacccgctctgccagttccag
tacatctgcagctgcctgcacagtgggttgacccctcacctgaccatggtccattcctcc
tccatcctcgccatgcgggatgagcagagcaaccctgcaccccaggtccagaaaccgcgt
gccaaaccacctcccattcctgcgaagaagccttcctctgtgtccctgtggtccctggag
cagccgttccgcatcgagctcatccagggcagcaaagtgaacgccgacgagcggatgaag
ctggtggtgcaggccgggcttttccacggcaacgagatgctgtgcaagacggtgtccagc
tcggaggtgagcgtgtgctcggagcccgtgtggaagcagcggctggagttcgacatcaac
atctgcgacctgccccgcatggcccgtctctgctttgcgctgtacgccgtgatcgagaaa
gccaagaaggctcgctccaccaagaagaagtccaagaaggcggactgccccattgcctgg
gccaacctcatgctgtttgactacaaggaccagcttaagaccggggaacgctgcctctac
atgtggccctccgtcccagatgagaagggcgagctgctgaaccccacgggcactgtgcgc
agtaaccccaacacggatagcgccgccgccctgctcatctgcctgcccgaggtggccccg
caccccgtgtactaccccgccctggagaagatcttggagctggggcgacacagcgagtgt
gtgcatgtcaccgaggaggagcagctgcagctgcgggaaatcctggagcggcgggggtct
ggggagctgtatgagcacgagaaggacctggtgtggaagctgcggcatgaagtccaggag
cacttcccggaggcgctagcccggctgctgctggtcaccaagtggaacaagcatgaggat
gtggcccagatgctctacctgctgtgctcctggccggagctgcccgtcctgagcgccctg
gagctgctagacttcagcttccccgattgccacgtaggctcctttgccatcaagtcgctg
cggaaactgacggacgatgagctgttccagtacctgctgcagctggtgcaggtgctcaag
tacgagtcctacctggactgcgagctgaccaaattcctgctggaccgggccctggccaac
cgcaagatcggccacttccttttctggcacctccgctccgagatgcacgtgccgtcggtg
gccctgcgcttcggcctcatcctggaggcctactgcaggggcagcacccaccacatgaag
gtgctgatgaagcagggggaagcactgagcaaactgaaggccctgaatgacttcgtcaag
ctgagctctcagaagacccccaagccccagaccaaggagctgatgcacttgtgcatgcgg
caggaggcctacctagaggccctctcccacctgcagtccccactcgaccccagcaccctg
ctggctgaagtctgcgtggagcagtgcaccttcatggactccaagatgaagcccctgtgg
atcatgtacagcaacgaggaggcaggcagtggcagcagcgtgggcatcatctttaagaat
ggggatgacctccggcaggacatgctgaccctgcagatgatccagctcatggacgtcctg
tggaagcaggaggggctggacctgaggatgaccccctacggctgcctccccaccggggac
cgcacaggcctcattgaggtggtactccgttcagacaccatcgccaacatccaactcaac
aagagcaacatggcagccacagccgccttcaacaaggacgccctgctcaactggctgaag
tccaagaacccgggggaggccctggatcgagccattgaggagttcaccctctcctgtgct
ggctattgtgtggccacatacgtgctgggcattggcgatcggcacagcgacaacatcatg
atccgagagagtgggcagctgttccacattgattttggccactttctggggaatttcaag
accaagtttggaatcaaccgcgagcgtgtcccattcatcctcacctatgactttgtccat
gtgattcagcaggggaagactaataatagtgagaaatttgaacggttccggggctactgt
gaaagggcctacaccatcctgcggcgccacgggcttctcttcctccacctctttgccctg
atgcgggcggcaggcctgcctgagctcagctgctccaaagacatccagtatctcaaggac
tccctggcactggggaaaacagaggaggaggcactgaagcacttccgagtgaagtttaac
gaagccctccgtgagagctggaaaaccaaagtgaactggctggcccacaacgtgtccaaa
gacaacaggcagtag

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