KEGG   Gorilla gorilla gorilla (western lowland gorilla): 101146434Help
Entry
101146434         CDS       T02442                                 

Gene name
PIK3CD
Definition
phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
Orthology
K00922  
phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
Organism
ggo  Gorilla gorilla gorilla (western lowland gorilla)
Pathway
Inositol phosphate metabolism
ErbB signaling pathway
Ras signaling pathway
Rap1 signaling pathway
Chemokine signaling pathway
HIF-1 signaling pathway
FoxO signaling pathway
Phosphatidylinositol signaling system
mTOR signaling pathway
PI3K-Akt signaling pathway
Apoptosis
Adrenergic signaling in cardiomyocytes
VEGF signaling pathway
Osteoclast differentiation
Focal adhesion
Toll-like receptor signaling pathway
Jak-STAT signaling pathway
Natural killer cell mediated cytotoxicity
T cell receptor signaling pathway
B cell receptor signaling pathway
Fc epsilon RI signaling pathway
Fc gamma R-mediated phagocytosis
TNF signaling pathway
Leukocyte transendothelial migration
Neurotrophin signaling pathway
Cholinergic synapse
Inflammatory mediator regulation of TRP channels
Regulation of actin cytoskeleton
Insulin signaling pathway
Progesterone-mediated oocyte maturation
Estrogen signaling pathway
Prolactin signaling pathway
Thyroid hormone signaling pathway
Oxytocin signaling pathway
Type II diabetes mellitus
Non-alcoholic fatty liver disease (NAFLD)
Aldosterone-regulated sodium reabsorption
Carbohydrate digestion and absorption
Bacterial invasion of epithelial cells
Chagas disease (American trypanosomiasis)
Toxoplasmosis
Amoebiasis
Hepatitis C
Hepatitis B
Measles
Influenza A
HTLV-I infection
Epstein-Barr virus infection
Pathways in cancer
Viral carcinogenesis
Proteoglycans in cancer
Colorectal cancer
Renal cell carcinoma
Pancreatic cancer
Endometrial cancer
Glioma
Prostate cancer
Melanoma
Chronic myeloid leukemia
Acute myeloid leukemia
Small cell lung cancer
Non-small cell lung cancer
Class
Metabolism; Carbohydrate metabolism; Inositol phosphate metabolism [PATH:ggo00562]
Environmental Information Processing; Signal transduction; Ras signaling pathway [PATH:ggo04014]
Environmental Information Processing; Signal transduction; Rap1 signaling pathway [PATH:ggo04015]
Environmental Information Processing; Signal transduction; ErbB signaling pathway [PATH:ggo04012]
Environmental Information Processing; Signal transduction; VEGF signaling pathway [PATH:ggo04370]
Environmental Information Processing; Signal transduction; Jak-STAT signaling pathway [PATH:ggo04630]
Environmental Information Processing; Signal transduction; TNF signaling pathway [PATH:ggo04668]
Environmental Information Processing; Signal transduction; HIF-1 signaling pathway [PATH:ggo04066]
Environmental Information Processing; Signal transduction; FoxO signaling pathway [PATH:ggo04068]
Environmental Information Processing; Signal transduction; Phosphatidylinositol signaling system [PATH:ggo04070]
Environmental Information Processing; Signal transduction; PI3K-Akt signaling pathway [PATH:ggo04151]
Environmental Information Processing; Signal transduction; mTOR signaling pathway [PATH:ggo04150]
Cellular Processes; Cell motility; Regulation of actin cytoskeleton [PATH:ggo04810]
Cellular Processes; Cell growth and death; Apoptosis [PATH:ggo04210]
Cellular Processes; Cell communication; Focal adhesion [PATH:ggo04510]
Organismal Systems; Immune system; Toll-like receptor signaling pathway [PATH:ggo04620]
Organismal Systems; Immune system; Natural killer cell mediated cytotoxicity [PATH:ggo04650]
Organismal Systems; Immune system; T cell receptor signaling pathway [PATH:ggo04660]
Organismal Systems; Immune system; B cell receptor signaling pathway [PATH:ggo04662]
Organismal Systems; Immune system; Fc epsilon RI signaling pathway [PATH:ggo04664]
Organismal Systems; Immune system; Fc gamma R-mediated phagocytosis [PATH:ggo04666]
Organismal Systems; Immune system; Leukocyte transendothelial migration [PATH:ggo04670]
Organismal Systems; Immune system; Chemokine signaling pathway [PATH:ggo04062]
Organismal Systems; Endocrine system; Insulin signaling pathway [PATH:ggo04910]
Organismal Systems; Endocrine system; Estrogen signaling pathway [PATH:ggo04915]
Organismal Systems; Endocrine system; Progesterone-mediated oocyte maturation [PATH:ggo04914]
Organismal Systems; Endocrine system; Prolactin signaling pathway [PATH:ggo04917]
Organismal Systems; Endocrine system; Oxytocin signaling pathway [PATH:ggo04921]
Organismal Systems; Endocrine system; Thyroid hormone signaling pathway [PATH:ggo04919]
Organismal Systems; Circulatory system; Adrenergic signaling in cardiomyocytes [PATH:ggo04261]
Organismal Systems; Digestive system; Carbohydrate digestion and absorption [PATH:ggo04973]
Organismal Systems; Excretory system; Aldosterone-regulated sodium reabsorption [PATH:ggo04960]
Organismal Systems; Nervous system; Cholinergic synapse [PATH:ggo04725]
Organismal Systems; Nervous system; Neurotrophin signaling pathway [PATH:ggo04722]
Organismal Systems; Sensory system; Inflammatory mediator regulation of TRP channels [PATH:ggo04750]
Organismal Systems; Development; Osteoclast differentiation [PATH:ggo04380]
Human Diseases; Cancers; Pathways in cancer [PATH:ggo05200]
Human Diseases; Cancers; Proteoglycans in cancer [PATH:ggo05205]
Human Diseases; Cancers; Viral carcinogenesis [PATH:ggo05203]
Human Diseases; Cancers; Colorectal cancer [PATH:ggo05210]
Human Diseases; Cancers; Pancreatic cancer [PATH:ggo05212]
Human Diseases; Cancers; Glioma [PATH:ggo05214]
Human Diseases; Cancers; Acute myeloid leukemia [PATH:ggo05221]
Human Diseases; Cancers; Chronic myeloid leukemia [PATH:ggo05220]
Human Diseases; Cancers; Melanoma [PATH:ggo05218]
Human Diseases; Cancers; Renal cell carcinoma [PATH:ggo05211]
Human Diseases; Cancers; Prostate cancer [PATH:ggo05215]
Human Diseases; Cancers; Endometrial cancer [PATH:ggo05213]
Human Diseases; Cancers; Small cell lung cancer [PATH:ggo05222]
Human Diseases; Cancers; Non-small cell lung cancer [PATH:ggo05223]
Human Diseases; Endocrine and metabolic diseases; Type II diabetes mellitus [PATH:ggo04930]
Human Diseases; Endocrine and metabolic diseases; Non-alcoholic fatty liver disease (NAFLD) [PATH:ggo04932]
Human Diseases; Infectious diseases; Bacterial invasion of epithelial cells [PATH:ggo05100]
Human Diseases; Infectious diseases; HTLV-I infection [PATH:ggo05166]
Human Diseases; Infectious diseases; Measles [PATH:ggo05162]
Human Diseases; Infectious diseases; Influenza A [PATH:ggo05164]
Human Diseases; Infectious diseases; Hepatitis B [PATH:ggo05161]
Human Diseases; Infectious diseases; Hepatitis C [PATH:ggo05160]
Human Diseases; Infectious diseases; Epstein-Barr virus infection [PATH:ggo05169]
Human Diseases; Infectious diseases; Amoebiasis [PATH:ggo05146]
Human Diseases; Infectious diseases; Toxoplasmosis [PATH:ggo05145]
Human Diseases; Infectious diseases; Chagas disease (American trypanosomiasis) [PATH:ggo05142]
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Position
1
AA seq 1044 aa AA seqDB search
MPPGVDCPMEFWTKEENQSVVVDFLLPTGVYLNFPVSRNANLSTIKQLLWHRAQYEPLFH
MLSGPEAYVFTCINQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLCDPEVNDFRAKMCQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARTWGP
GTLRLPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGRHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
AKPPPIPAKKPSSVSLWSLEQPFRIELIQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVSVCSEPVWKQRLEFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNPTGTVRSNPNTDSAAALLICLPEVAP
HPVYYPALEKILELGRHSECVHVTEEEQLQLREILERRGSGELYEHEKDLVWKLRHEVQE
HFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDCHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSV
ALRFGLILEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKLSSQKTPKPQTKELMHLCMR
QEAYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWIMYSNEEAGSGSSVGIIFKN
GDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLRSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
ERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
NT seq 3135 nt NT seq  +upstreamnt  +downstreamnt
atgccccctggggtggactgccccatggaattctggaccaaggaggagaatcagagcgtc
gtggttgacttcctgctgcccacaggggtctacctgaacttccctgtgtcccgcaatgcc
aacctcagcaccatcaagcagctgctgtggcaccgcgcccagtatgagccgctcttccac
atgctcagtggccccgaggcctatgtgttcacctgcatcaaccagacagcggagcagcaa
gagttggaggacgagcaacggcgtctgtgtgacgtgcagcccttcctgcccgtcctgcgc
ctggtggcccgtgagggcgaccgcgtgaagaagctcatcaactcacagatcagcctcctc
atcggcaaaggcctccacgagtttgactccttgtgcgacccagaagtgaacgactttcgc
gccaagatgtgccaattctgcgaggaggcggccgcccgccggcagcagctgggctgggag
gcctggctgcagtacagtttccccctgcagctggagccctcagctcgaacctgggggcct
ggcaccctgcggctcccgaaccgggcccttctggtcaacgttaagtttgagggcagcgag
gaaagcttcaccttccaggtgtccaccaaggatgtgccgctggcgctgatggcctgtgcc
ctgcggaagaaggccacggtgttccggcagccgctggtggagcagccagaagactacacg
ctgcaggtgaacggcaggcatgagtacctgtatggcagctacccgctctgccagttccag
tacatctgcagctgcctgcacagtgggttgacccctcacctgaccatggtccattcctcc
tccatcctcgccatgcgggatgagcagagcaaccctgcaccccaggtccagaaaccgcgt
gccaaaccacctcccattcctgcgaagaagccttcctctgtgtccctgtggtccctggag
cagccgttccgcatcgagctcatccagggcagcaaagtgaacgccgacgagcggatgaag
ctggtggtgcaggccgggcttttccacggcaacgagatgctgtgcaagacggtgtccagc
tcggaggtgagcgtgtgctcggagcccgtgtggaagcagcggctggagttcgacatcaac
atctgcgacctgccccgcatggcccgtctctgctttgcgctgtacgccgtgatcgagaaa
gccaagaaggctcgctccaccaagaagaagtccaagaaggcggactgccccattgcctgg
gccaacctcatgctgtttgactacaaggaccagcttaagaccggggaacgctgcctctac
atgtggccctccgtcccagatgagaagggcgagctgctgaaccccacgggcactgtgcgc
agtaaccccaacacggatagcgccgccgccctgctcatctgcctgcccgaggtggccccg
caccccgtgtactaccccgccctggagaagatcttggagctggggcgacacagcgagtgt
gtgcatgtcaccgaggaggagcagctgcagctgcgggaaatcctggagcggcgggggtct
ggggagctgtatgagcacgagaaggacctggtgtggaagctgcggcatgaagtccaggag
cacttcccggaggcgctagcccggctgctgctggtcaccaagtggaacaagcatgaggat
gtggcccagatgctctacctgctgtgctcctggccggagctgcccgtcctgagcgccctg
gagctgctagacttcagcttccccgattgccacgtaggctcctttgccatcaagtcgctg
cggaaactgacggacgatgagctgttccagtacctgctgcagctggtgcaggtgctcaag
tacgagtcctacctggactgcgagctgaccaaattcctgctggaccgggccctggccaac
cgcaagatcggccacttccttttctggcacctccgctccgagatgcacgtgccgtcggtg
gccctgcgcttcggcctcatcctggaggcctactgcaggggcagcacccaccacatgaag
gtgctgatgaagcagggggaagcactgagcaaactgaaggccctgaatgacttcgtcaag
ctgagctctcagaagacccccaagccccagaccaaggagctgatgcacttgtgcatgcgg
caggaggcctacctagaggccctctcccacctgcagtccccactcgaccccagcaccctg
ctggctgaagtctgcgtggagcagtgcaccttcatggactccaagatgaagcccctgtgg
atcatgtacagcaacgaggaggcaggcagtggcagcagcgtgggcatcatctttaagaat
ggggatgacctccggcaggacatgctgaccctgcagatgatccagctcatggacgtcctg
tggaagcaggaggggctggacctgaggatgaccccctacggctgcctccccaccggggac
cgcacaggcctcattgaggtggtactccgttcagacaccatcgccaacatccaactcaac
aagagcaacatggcagccacagccgccttcaacaaggacgccctgctcaactggctgaag
tccaagaacccgggggaggccctggatcgagccattgaggagttcaccctctcctgtgct
ggctattgtgtggccacatacgtgctgggcattggcgatcggcacagcgacaacatcatg
atccgagagagtgggcagctgttccacattgattttggccactttctggggaatttcaag
accaagtttggaatcaaccgcgagcgtgtcccattcatcctcacctatgactttgtccat
gtgattcagcaggggaagactaataatagtgagaaatttgaacggttccggggctactgt
gaaagggcctacaccatcctgcggcgccacgggcttctcttcctccacctctttgccctg
atgcgggcggcaggcctgcctgagctcagctgctccaaagacatccagtatctcaaggac
tccctggcactggggaaaacagaggaggaggcactgaagcacttccgagtgaagtttaac
gaagccctccgtgagagctggaaaaccaaagtgaactggctggcccacaacgtgtccaaa
gacaacaggcagtag

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