KEGG   Gossypium hirsutum (upland cotton): 107905452
Entry
107905452         CDS       T04793                                 
Name
(RefSeq) bifunctional dihydrofolate reductase-thymidylate synthase
  KO
K13998  dihydrofolate reductase / thymidylate synthase [EC:1.5.1.3 2.1.1.45]
Organism
ghi  Gossypium hirsutum (upland cotton)
Pathway
ghi00240  Pyrimidine metabolism
ghi00670  One carbon pool by folate
ghi00790  Folate biosynthesis
ghi01100  Metabolic pathways
ghi01232  Nucleotide metabolism
ghi01240  Biosynthesis of cofactors
Module
ghi_M00126  Tetrahydrofolate biosynthesis, GTP => THF
ghi_M00938  Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP
Brite
KEGG Orthology (KO) [BR:ghi00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00240 Pyrimidine metabolism
    107905452
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    107905452
   00670 One carbon pool by folate
    107905452
Enzymes [BR:ghi01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.3  dihydrofolate reductase
     107905452
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.45  thymidylate synthase
     107905452
SSDB
Motif
Pfam: DHFR_1
Other DBs
NCBI-GeneID: 107905452
NCBI-ProteinID: XP_016687598
UniProt: A0A1U8JFU3
Position
D05:17317960..17320092
AA seq 267 aa
MLTRLQSNKLFSKVLLSRYKNGFPNLISGSQFLRGFNEIAKHGFSVMSGDNLRSLSNSAS
PRNYRVVVAATREMGIGKDGKLPWRLPSDLKFFKELTVTTSDPEKKNAVVMGRKTWESIP
LEFRPLPGRLNVVLTRSQSSDITTGENVVICGSIPSAFELLAEDPYCFSIEKVFVIGGGQ
IFRETLNAPGCEAIHITEIGTSIECDTFIPSIDSSCFQLLYSSKPLEENNVRFSFATYVR
VRSRTTDNYEVKDLSFLPRMIVERRDE
NT seq 804 nt   +upstreamnt  +downstreamnt
atgttgacgcgtctgcagagtaacaaacttttctccaaggttcttctgagtcgttacaaa
aatgggtttcccaatcttatctctgggtctcaatttttaagaggttttaacgagattgca
aagcatgggttttctgtaatgtcgggtgataatctacggagcctatctaacagtgcttcc
ccgaggaattaccgagtcgtagtggctgcaactcgtgaaatgggaatagggaaagatggc
aagttgccatggagattgccttctgatctcaaattcttcaaggaacttacagtgacaaca
tcagatcctgagaagaagaatgctgtagtaatgggtagaaaaacctgggagagtattcca
cttgagtttagacctttacccggtcgcctgaatgttgtccttactcgttcccagagttct
gatattacaactggagaaaatgttgtaatatgtgggagcattccatcagctttcgaacta
ttagccgaggatccttattgtttttcaatagagaaggtgtttgtcattggcggtggccag
atattcagggaaacactcaatgctccaggttgcgaagccattcacattactgaaattggg
acaagcattgaatgcgataccttcattccttcaattgactcgtcttgtttccagctgttg
tactcttcgaagccattggaagaaaataatgtccggttttcatttgcaacttatgttcgt
gttagatctaggacaactgataattatgaggtaaaagacttgagtttcttgcccaggatg
attgttgagagacgagatgaatga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (9)   
   KEGG PATHWAY (6)   
   KEGG MODULE (3)   
Chemical substance (11)   
   KEGG COMPOUND (11)   
Chemical reaction (9)   
   KEGG ENZYME (2)   
   KEGG REACTION (7)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (3)   
   RefSeq(nuc) (1)   
   GenBank (1)   
   EMBL (1)   
Protein domain (1)   
   Pfam (1)   
All databases (42)   

Download RDF
DBGET integrated database retrieval system