KEGG   GLYCAN: G00093Help
Entry
G00093                      Glycan                                 

Name Globotriaosylceramide;
Gb3Cer;
Pk antigen;
CD77
Composition (Gal)2 (Glc)1 (Cer)1
Mass 486.4 (Cer)
Structure
KCF fileKCaMKegDraw
Class Glycolipid; Sphingolipid
BRITE hierarchy
Remark Same as: C04737
Reference











1  [PMID:12227795]
Bosse F, Marcaurelle LA, Seeberger PH.
Linear synthesis of the tumor-associated carbohydrate antigens
Globo-H, SSEA-3, and Gb3.
J. Org. Chem. 67 (2002) 6659-70.
2  [PMID:2960671]
Holmes EH, Hakomori S, Ostrander GK.
Synthesis of type 1 and 2 lacto series glycolipid antigens in human
colonic adenocarcinoma and derived cell lines is due to activation
of a normally unexpressed beta
1----3N-acetylglucosaminyltransferase.
J. Biol. Chem. 262 (1987) 15649-58.
Reaction R05960 R05961 R05962 R05963
Pathway PATH: ko00603  Glycosphingolipid biosynthesis - globo series
PATH: ko01100  Metabolic pathways
Enzyme 2.4.1.79        2.4.1.228       3.2.1.22        3.2.1.47
3.2.1.52
Orthology KO: K00719  galactosylgalactosylglucosylceramide
            beta-D-acetylgalactosaminyltransferase [EC:2.4.1.79]
KO: K01189  alpha-galactosidase [EC:3.2.1.22]
KO: K01207  beta-N-acetylhexosaminidase [EC:3.2.1.52]
KO: K01988  lactosylceramide 4-alpha-galactosyltransferase
            [EC:2.4.1.228]
Other DBs CCSD:  291 293 2404 3587 4651 4778 5723 6241 7333 8268 9933 9987
      10297 10299 10869 11331 11641 11801 12378 14423 15149 15503
      15548 15725 15925 16227 16330 16353 16403 16460 16868 17111
      17680 17708 17928 18494 18545 18587 18633 18971 19298 21064
      21142 21348 21363 21369 22111 23006 23163 23388 23853 23876
      23918 24085 24122 24354 24435 24650 24766 25040 25302 25306
      25315 25321 25330 25520 25546 25555 25581 25794 25820 25981
      26179 26267 26597 26605 26614 26736 27232 27273 27542 27632
      28502 29096 29266 29958 30834 31630 31690 31941 31985 32048
      32591 32623 32730 32737 32740 33185 33204 33207 33213 33715
      33899 33971 34169 35082 35720 35922 35950 35959 36104 36156
      36463 36648 36860 36985 36991 36998 37049 37062 37067 37211
      37591 37604 37839 38016 38023 38085 38091 38132 38367 39383
      40782 41773 41869 41902 42044 42841 42982 43010 43023 43465
      43578 43605 43704 43796 44080 44226 44241 44612 44688 44992
      45293 45300 46811 47010 47195 47424 47632 47759 47782 47974
      48196 48204 48208 48225 48501 48732 49324 50141 50143 50463
GlycomeDB: 120
JCGGDB: JCGG-STR002182
LipidBank: GSG1328
KCF data Show

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