KEGG   Geobacillus thermocatenulatus: GT3921_15915
Entry
GT3921_15915      CDS       T05178                                 
Name
(GenBank) bifunctional homocysteine S-methyltransferase/methylenetetrahydrofolate reductase
  KO
K24042  methionine synthase / methylenetetrahydrofolate reductase (NADH) [EC:2.1.1.13 1.5.1.54]
Organism
gtm  Geobacillus thermocatenulatus
Pathway
gtm00270  Cysteine and methionine metabolism
gtm00450  Selenocompound metabolism
gtm00670  One carbon pool by folate
gtm01100  Metabolic pathways
gtm01110  Biosynthesis of secondary metabolites
gtm01120  Microbial metabolism in diverse environments
gtm01230  Biosynthesis of amino acids
Module
gtm_M00017  Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:gtm00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    GT3921_15915
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    GT3921_15915
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    GT3921_15915
Enzymes [BR:gtm01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.54  methylenetetrahydrofolate reductase (NADH)
     GT3921_15915
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     GT3921_15915
SSDB
Motif
Pfam: S-methyl_trans MTHFR DUF6506
Other DBs
NCBI-ProteinID: AST00381
UniProt: A0A226Q583
Position
3247462..3249309
AA seq 615 aa
MGLLDELKQRILIADGAMGTLLYSHGIDRCFEELNLSNPDEIIHIHEAYIAAGADVIQTN
TYGANYVKLARYGLQDEVPGINRAAVRLAKQAANGRAYVLGTIGGLRTLNKSVVTLEEVK
RTFREQLFVLLAEGIDGVLLETYYDLEELETVLAIARQETDLPIIAHVSLHEVGVLQDGT
PLADALSRLEALGADVVGLNCRLGPYYMIQSLEEVPLPKQAFLSAYPNASLPDYRDGRLV
YETNAEYFEETAKAFRDQGVRLIGGCCGTTPKHIEAMAKALADRTPVTEKTVKRRAVSVS
VQAERPAPTPLPELARTRRSVIVELDPPKQLGIDKFLAGAKALHDAGIDALTLADNSLAT
PRISNAAVATIIKERIGVRPLVHMTCRDRNLIGLQSHLMGLHTLGITDVLAITGDPSKIG
DFPGATSVYDLSSFDLIRLISQFNEGLSYSGKSLGQKTNFSIGAAFNPNVRHLDKAVERM
EKKIQCGAHYFLTQPVYSEEKIVQIYEATKHLDTPIYIGIMPLVSARNAEFLHHEVPGIT
LSDEIRARMAACGDDPVQAAREGIAIAKSLIDAAFDLFNGIYLITPFLRYDMTVELVRYI
HEKEAAAKERKVVHG
NT seq 1848 nt   +upstreamnt  +downstreamnt
gtggggctgctcgatgagttgaaacaacgcattctcatcgccgacggggcgatggggacg
cttctatattcgcacggcattgaccgttgttttgaagaattgaatttatccaatccagat
gaaatcattcatattcacgaggcgtatatcgcggcaggcgccgatgtcattcagacgaat
acatacggcgccaactatgtgaaactcgcgcgctacggcttgcaagacgaggtgccgggg
atcaatcgcgccgctgtaaggctggcgaaacaagcagcaaatgggcgggcgtacgtactc
ggaacgatcggagggctgcgcacgttaaacaaaagcgtcgtcacgctcgaagaagtgaag
cggacgtttcgcgagcagctgtttgtgctgctggctgaagggatcgacggcgtgttgctt
gagacgtattacgatttggaagagttggagacggtgcttgccatcgcccgccaagagacc
gacttgccgattatcgctcacgtctcgcttcatgaagtcggcgtcttgcaagatggcacg
ccgcttgcggacgcccttagccgcctggaggcgctcggggccgatgtcgtcgggctcaac
tgccgccttgggccgtactatatgattcagtcgctcgaggaagtgcccctgccaaagcaa
gcgtttttatcggcgtatccgaacgccagcctccctgattaccgcgacggccggctcgtg
tacgagacgaacgccgaatatttcgaggagacggccaaagcgttccgcgaccaaggggtg
cgcttgatcggcggctgctgcggcacgacgccaaaacatattgaagcgatggcaaaggcg
ctcgccgatcggacgccggtgacggaaaaaacggtgaagcggcgcgcagtgtcggtatcg
gtgcaagccgagcggcccgcgccgactccgcttcccgagcttgcccgcacgcgccgctcg
gtcattgtcgaactcgacccgccgaaacaactcggcattgacaagtttctcgctggggcg
aaagcgctccatgacgctggcatcgacgcgctgacgttagctgacaactcgcttgccacg
ccgcgcatcagcaacgccgccgtcgccacgatcatcaaagagcggatcggcgtccgcccg
ctcgtgcatatgacatgccgagaccgcaatttgatcggcttgcagtcgcatttgatgggc
ttgcatacgcttggcatcaccgacgtgctcgccattaccggcgacccgtcgaaaatcggc
gacttcccaggagcaacgtccgtgtacgacttatcatcgttcgatttgatccgtttgatc
agccaatttaacgaaggactgtcgtactcgggcaaatcactcggacaaaaaacgaacttc
tcgatcggcgcggcgttcaacccgaacgtccgccatttggataaagcggttgagcgaatg
gagaaaaaaattcaatgcggcgcccactatttcttgacccagccggtttactcggaagaa
aaaatcgtgcaaatatacgaagcgacgaaacatctcgacacgccgatctacattggcatc
atgccgctggtgagcgcgcgcaacgccgagtttttgcatcatgaagtgccggggatcacc
ctgtcggacgagattcgcgcccgcatggccgcctgcggcgacgacccggtgcaagcagcg
cgcgaagggatcgccatcgccaaatcgctcattgacgcggcattcgatttgtttaacggc
atttacttgatcacgccgtttttgcgctatgacatgacggtcgagctcgtccgctacatt
cacgaaaaagaagcggccgccaaagaaaggaaggttgttcatggctaa

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (8)   
   KEGG PATHWAY (7)   
   KEGG MODULE (1)   
Chemical substance (12)   
   KEGG COMPOUND (12)   
Chemical reaction (5)   
   KEGG ENZYME (2)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (3)   
   Pfam (3)   
All databases (35)   

Download RDF
DBGET integrated database retrieval system