KEGG T00915: GWCH70

Geobacillus sp. WCH70: GWCH70_0707

Entry

GWCH70_0707 CDS T00915

Definition

methionine synthase

Orthology

K00548

5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]

Organism

gwc Geobacillus sp. WCH70

Pathway

gwc00270	Cysteine and methionine metabolism
gwc00450	Selenocompound metabolism
gwc00670	One carbon pool by folate
gwc01100	Metabolic pathways
gwc01110	Biosynthesis of secondary metabolites
gwc01230	Biosynthesis of amino acids

Module

gwc_M00017

Methionine biosynthesis, apartate => homoserine => methionine

Class

Metabolism; Amino acid metabolism; Cysteine and methionine metabolism [PATH:gwc00270]
Metabolism; Metabolism of other amino acids; Selenocompound metabolism [PATH:gwc00450]
Metabolism; Metabolism of cofactors and vitamins; One carbon pool by folate [PATH:gwc00670]

SSDB

Motif

Pfam:

S-methyl_trans Met_synt_B12 Pterin_bind B12-binding_2 B12-binding CdhD His_biosynth Clathrin_H_link

Other DBs

NCBI-GI:

NCBI-GeneID:

JGI:

UniProt:

Position

complement(781560..784970)

AA seq 1136 aa
MGNITLEQQLEKKILIIDGAMGTMIQSAKLSADDFGGEAYEGCNEYLTLTAPHVIERIHE
AYLQAGADIIETNTFGATNVVLDEYHLGHLALELNIEAARLARKAADAYSTPEWPRFVAG
SMGPTTKTLSVTGGITFEQLVAAYEEQARGLLLGGVDLLLLETCQDTLNVKAGFIGISKA
FEAVGKQVPIMISGTIEPMGTTLAGQTIESFFISVQHMKPFAVGLNCATGPEFMTDHLRA
LASLANTAVSCYPNAGLPDEEGCYHETPEMLAKKIRRFAEKGWINIVGGCCGTTPEHIRA
IAEAVRDIPPRPIPKSFDVHAVSGIDPLIYDETMRPLFVGERTNVIGSRKFKRLIAEGKY
EEAAEIARAQVKNGAHVIDICLADPDRNEQEDMEKFIQQVVKKVKVPLVIDSTDERVIER
ALTYSQGKAIINSINLEDGEERFEKVIPLLHKYGAAVVVGTIDEQGMAIHAERKLEIALR
SHDLLVNKYGVSPHDIIFDPLVFPVGTGDEQYIGAAKETIEGIRLIKERLPQCLTILGIS
NVSFGLPPVGREILNSVFLYHCTQAGLDYAIVNTEKLERFASIPEEEVRLAEELLFNTND
ETLNTFIQFYRDKTKEPKKIKTELSLEERLAGYVVEGTKEGLYADLEQALQTYSDPLDII
NGPLMEGMDEVGRLFNNNQLIVAEVLQSAEVMKAAVAFLEPYMEKKENSTKGKVLLATVK
GDVHDIGKNLVDIILSNNGFHVIDLGIKVAPQKLIEAVQAEKPDIIGLSGLLVKSAQQMV
VTAQDLRQAGISIPILVGGAALSRKFTENKIAPEYDGIVLYAKDAMEGLALANQLQQNEI
EYTKTKKQETETEKTTPTAIAAKSNVSTDVPVFVPTDLERHILKDISLSHIIPYVNWQMV
LGHHLGLKGKVKRLLEEKDEKALMLKQVVDDLLDEAQRNNWITPAAVYQFFPAQSEGNRI
YIYSPKDKRTIIEMFEFPRQPREPYLCLADYLKSTESGQIDYVGFFAVTAGKGIRELSQR
WKESGEFLKSHAIQALALEIAEGLAELIHQVMRDRWGFPDDPDFTMEQRFAAKYQGQRYS
FGYPACPNLEDQEKLFRLLNPEEIGIHLTDGYMMEPEASVSAIVFAHPEARYFNVL

NT seq 3411 nt +upstreamnt +downstreamnt
atgggtaacatcacacttgagcaacagctcgaaaaaaaaatattaattattgacggcgca
atgggaacgatgattcaaagcgcgaagctctcagctgatgatttcggcggagaagcatac
gaaggatgcaacgaatatttgacgctcaccgcccctcatgtgatcgagcgcattcatgaa
gcatatttgcaggcgggagcggatattatcgaaacaaacacgttcggtgcgacaaacgtt
gtattagatgaatatcatcttggccatttagcgctagagttaaatatcgaagcagccagg
cttgcccgcaaagccgccgatgcctactctactcccgaatggccgcgctttgtcgctggt
tcgatggggccgacgacaaaaacgttatccgtcacaggaggcattacgttcgaacaatta
gttgccgcttacgaagaacaagcgcgtggactattgcttggcggagtcgacttactttta
ttagaaacgtgccaagacaccttaaacgtcaaagccggctttatcggcatttccaaggcg
tttgaagcggttggaaaacaagtaccgattatgatttccgggacgattgaaccaatggga
acaacattagcaggacaaacgattgaatcgtttttcatctccgtccagcatatgaagccg
ttcgcggtcggattaaactgcgcgaccggccccgagtttatgaccgaccatttgcgcgcg
ctcgcttccttggcgaacactgctgtaagctgctatccgaacgccgggcttccggatgaa
gaaggatgctatcacgagacaccggagatgttagcgaaaaaaatccgacgattcgctgaa
aaaggatggattaacatcgtcggcggctgttgcggaacaaccccggaacatattcgcgcc
atcgccgaagcggtccgggacattccaccgcggccaattccgaaatcttttgacgttcat
gccgtctccggcatcgatccgcttatttacgatgaaacaatgcgtccgctgtttgtcggc
gagcgcacaaacgtaatcggttcgcgcaaatttaaacggctcatcgccgaaggaaaatat
gaagaagcggcggaaattgcccgcgcgcaagtaaaaaacggcgcgcacgtcatcgatatt
tgcttagccgacccggaccgcaacgaacaagaagatatggaaaagtttatccaacaagtc
gtaaaaaaagtaaaagtgccgcttgtcattgattcgacggatgaacgcgttattgaacgc
gctctcacttattcacaagggaaagcaatcattaactcgattaatttggaagacggcgaa
gaacggtttgaaaaagtcattcctctccttcacaaatatggtgctgccgtcgttgtcgga
acgattgatgaacagggaatggcgattcatgctgagcggaagctggaaatcgccttgcgt
tcgcatgacttgctcgtcaacaaatacggagtttccccgcatgacattatttttgacccg
cttgtgttcccggtcggcaccggcgatgaacaatatattggcgcggccaaggaaacgatc
gaaggcatccgtctcattaaagaacggcttccgcaatgtttaacaatacttggcatcagc
aatgtctcattcgggcttccgccggttgggcgggaaattttaaactccgtctttttgtac
cattgcacgcaggccgggctcgattacgcgatcgtcaatacggaaaaattggagcgattc
gcttcgattccggaagaagaagtgcggttggctgaagaactgctgtttaacacgaacgat
gaaacgttaaacacgtttatccaattttaccgcgataaaacgaaagaaccgaaaaaaata
aaaaccgagcttagccttgaggagcggctcgcgggctatgtcgtcgaaggcacgaaagaa
ggattgtacgccgatttggaacaagcgctgcaaacgtattccgacccgcttgacatcatt
aacggaccgctgatggaggggatggatgaagttgggcggctgtttaataacaatcaactc
attgttgccgaagtattacaaagcgcggaagtgatgaaagcagcggtcgcctttttagaa
ccatatatggagaaaaaggaaaacagtacaaaaggaaaagtgcttctcgccactgtcaag
ggcgatgtgcatgacatcggcaaaaacttggtcgacatcattttaagcaacaacggcttt
cacgtcatcgacctaggcattaaagtggcgccgcaaaagctgatcgaagccgttcaagcc
gaaaaaccggatattatcggtttatcagggcttcttgtcaaatccgcccagcaaatggtc
gtcaccgcgcaagatttgcggcaagcgggcatctcgattccgattttagtcggcggtgcg
gcattatcgcgtaaattcacggaaaacaaaatcgctccggaatatgatggaatcgtatta
tacgcaaaagacgccatggaaggactggcgctggcaaatcagctgcagcaaaacgaaatc
gaatatacaaaaacaaaaaagcaagaaacggaaacagaaaaaacgacaccaacggctatt
gcggcaaagtcgaacgtctcgaccgacgttcccgtgtttgtgccaacagatttagaacgc
catatattgaaagatatttcgctttcgcatattattccatacgtcaactggcaaatggta
ttaggacatcaccttgggttaaaaggaaaagtaaaacggctgcttgaggaaaaagatgaa
aaagcgcttatgttaaagcaagtcgtcgatgacctgcttgacgaggcccagcgcaacaac
tggattacgccagcggcggtatatcaatttttcccggcgcaaagtgaaggaaaccggatt
tacatttactcgccaaaagacaaacggaccattatcgaaatgtttgaatttccaagacag
ccaagagagccatacctttgtttagctgattacttgaaatctacagaaagcggacaaatc
gactatgtgggatttttcgccgtcaccgccggaaaaggcattcgcgaactttcgcagcga
tggaaagaaagcggcgaatttttaaaaagtcatgcgattcaagcgctggcgctcgaaatc
gccgaaggattagcggagctcatccaccaagtcatgcgcgaccgctggggctttccggat
gatccggatttcacgatggaacagcgctttgccgcgaaataccaagggcagcgctactcg
ttcggctatccggcttgcccgaacttggaagaccaagaaaagctcttccgtctattgaac
ccagaagaaatcggcatccatttaacggacggatatatgatggagccggaagcttccgtt
tccgcgattgtctttgcccatccagaagcgcgctatttcaatgtgttataa

All links

Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (5)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (1)   
   JGI-GWC (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
Protein domain (8)   
   Pfam (8)   
All databases (34)   

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