KEGG   Hipposideros armiger (great roundleaf bat): 109389346
Entry
109389346         CDS       T04661                                 
Symbol
MET
Name
(RefSeq) hepatocyte growth factor receptor
  KO
K05099  proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
Organism
hai  Hipposideros armiger (great roundleaf bat)
Pathway
hai01521  EGFR tyrosine kinase inhibitor resistance
hai04010  MAPK signaling pathway
hai04014  Ras signaling pathway
hai04015  Rap1 signaling pathway
hai04020  Calcium signaling pathway
hai04151  PI3K-Akt signaling pathway
hai04360  Axon guidance
hai04510  Focal adhesion
hai04520  Adherens junction
hai05100  Bacterial invasion of epithelial cells
hai05144  Malaria
hai05200  Pathways in cancer
hai05202  Transcriptional misregulation in cancer
hai05205  Proteoglycans in cancer
hai05206  MicroRNAs in cancer
hai05208  Chemical carcinogenesis - reactive oxygen species
hai05211  Renal cell carcinoma
hai05218  Melanoma
hai05223  Non-small cell lung cancer
hai05225  Hepatocellular carcinoma
hai05226  Gastric cancer
hai05230  Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:hai00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    109389346 (MET)
   04014 Ras signaling pathway
    109389346 (MET)
   04015 Rap1 signaling pathway
    109389346 (MET)
   04020 Calcium signaling pathway
    109389346 (MET)
   04151 PI3K-Akt signaling pathway
    109389346 (MET)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    109389346 (MET)
   04520 Adherens junction
    109389346 (MET)
 09150 Organismal Systems
  09158 Development and regeneration
   04360 Axon guidance
    109389346 (MET)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    109389346 (MET)
   05202 Transcriptional misregulation in cancer
    109389346 (MET)
   05206 MicroRNAs in cancer
    109389346 (MET)
   05205 Proteoglycans in cancer
    109389346 (MET)
   05208 Chemical carcinogenesis - reactive oxygen species
    109389346 (MET)
   05230 Central carbon metabolism in cancer
    109389346 (MET)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    109389346 (MET)
   05226 Gastric cancer
    109389346 (MET)
   05218 Melanoma
    109389346 (MET)
   05211 Renal cell carcinoma
    109389346 (MET)
   05223 Non-small cell lung cancer
    109389346 (MET)
  09171 Infectious disease: bacterial
   05100 Bacterial invasion of epithelial cells
    109389346 (MET)
  09174 Infectious disease: parasitic
   05144 Malaria
    109389346 (MET)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    109389346 (MET)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hai01001]
    109389346 (MET)
Enzymes [BR:hai01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     109389346 (MET)
Protein kinases [BR:hai01001]
 Receptor tyrosine kinases (RTK)
  MET family
   109389346 (MET)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr TIG Pkinase Sema PSI Kinase-like Pkinase_fungal Linker_histone
Other DBs
NCBI-GeneID: 109389346
NCBI-ProteinID: XP_019510313
EnsemblRapid: ENSHARG00000012837
UniProt: A0A8B7SBY2
Position
Unknown
AA seq 1382 aa
MKAPAVLAPGLLLLLLTLVQKGSGECKAALMKSAMNVNMKYQLPNFTAETPIQNVVVHKH
YIYLGAINYIYVLNDRDLQKVAEYKTGPVLEHPDCFPCQGCSHKANVSGGVWKDNINMAL
LVDTYYDDQLISCGSVRRGTCQRHVLPPSSAADIQSEVHCMYSPQADEEPGQCPDCVVSA
LGTKVLLSEKERFINFFVGNTLNSSSPPDHALHSISVRRLKETQDGFKFLTDQSYIDVLP
EFRDSYPIKYVHAFESNHFIYFLTVQRETLDAQTFHTRIIRFCSIDSGLHSYMEMPLECI
LTEKRRKRSTRQEVFNILQAAYVSKPGAHLARQIGVNLDDDILYGVFAQSKPDSAEPTNR
SAVCAFPIKFINEFFNKIVNKNNVRCLQHFYGPNHEPCFNKTLLRIPSGCEVRSDEYRTE
FTTALQRVDLFMGQFTRVLLTSVSTFITDDLTIANLGTSEGRFMQVVVSRSGSSTPHVNF
RLDSHPVSPKMIVERPLNQNGYTLVVTGKTVTKIPLNGLGCEHFQSCSQCLSAPPFVQCG
WCHNKCVRLEECPSGVWTQDVCHPTIYKVFPISAPLEGGTTLTICGWDFGFRRNNKFDLK
KTRILLGNESCTLTLSESTANTLKCTVGPAMSEHLNLSIIISNGRGSAQYTAFSYVDPII
TSISPSYGPKTGGTLLTLTGKYLNSGNSRHISIGGKTCTLKSVSESILECYTPAQTTSTE
FPIKLKIDLANRETNSFSYQEDPIVEQIHPTKSFISGGSTITGVGKNLNSVSGLRMVINV
HEAGRNFTVACQHRSNSEIICCTTPSLQQLSLQLPLRTKAYFMLDGIHSKYFDLIYVHDP
VFKFFEKPVLISIGNENVLEIKGNDIDPEAVKGEVLKVGNKSCEKIQSHSEAVSCTVPSD
LLKLNNELNIEWKQAVSSTVLGKVIVQPDQDFTGLIVGVVSISVILSLLLGLFLWLKRRK
QIKDLGSELVRYDARVHTPHLDRLVSARSVSPTTEMVSNESVDYRATFPEEQFPNSSQNG
SCRQVQYPLMDLSPILPGGDSDVSSPLLQNTVRIDLSTLNPELVQAVQHVVIGPSSLIVH
FSEVIGRGHFGCVYHGTLLDNDDKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNV
LSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASKK
FVHRDLAARNCMLDENFTVKVADFGLARDVYDKEYYSVHNKTGAKLPVKWMALESLQTQK
FTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKC
WHPKAELRPSFAELVSRISAIFSAFIGEHYVHVNATYVNVKCVAPYPCLLSSQDHVDGEG
DT
NT seq 4149 nt   +upstreamnt  +downstreamnt
atgaaggcccccgctgtgctggcacctggcctcctcctgcttctgttgaccttggtgcag
aagggcagcggggagtgcaaagcggcgctcatgaagtctgcgatgaacgtgaacatgaag
taccagctgcccaacttcaccgcggaaacgcccatccagaatgtcgttgtgcacaagcat
tacatttacctgggtgccataaactacatttacgttttgaatgacagagaccttcagaag
gtggctgagtacaagacagggccggtgctggaacacccggactgtttcccatgtcagggc
tgcagccacaaggccaatgtctcagggggcgtttggaaagataacatcaacatggctctg
ctggtggacacgtactatgatgaccagctcatcagctgcggcagtgtccgcaggggcacc
tgccagcgacacgtgctgccgccctccagtgctgcggacatccagtccgaggtgcactgc
atgtactcgccgcaggccgatgaggagcccggccagtgtcccgactgcgtggtcagcgcc
ctgggaaccaaagtcctgctttcggagaaggagcggttcatcaacttcttcgtgggcaac
actctgaactcttcttcccctccagaccacgcgttacattcaatatcggtgagaaggctg
aaggaaacacaagatgggtttaagtttttgacagaccagtcctacattgatgttttgccc
gagttccgagattcttaccccattaagtatgtccacgcctttgaaagcaaccattttatt
tactttctgacggtccaacgggaaacccttgatgctcagacttttcacacgaggataatc
aggttctgttccatagactccgggttgcattcctacatggaaatgcctctggagtgtatt
ctcacagagaagagaagaaagcgatccaccaggcaggaagtgtttaacatcctccaagct
gcctacgtcagtaagcctggggcacatctcgccaggcagataggtgtcaacctggacgat
gacatcctctacggggtgtttgcacaaagcaagccagattccgccgagccaacaaatcgc
tccgccgtctgtgcgttcccgatcaagtttatcaatgaattcttcaacaagatcgtcaac
aaaaacaatgtgagatgtctccagcatttttatggacccaaccatgagccctgctttaat
aagacacttctgagaattccatcaggctgtgaagtgcgcagtgatgagtatcgcacggag
ttcaccaccgctttgcaacgcgttgacttattcatgggccagttcacccgagtcctcctg
acgtctgtatcaacgttcatcacagacgacctcaccatcgccaacctcgggacatcggag
ggtcgcttcatgcaggttgtggtttctcgatcaggatcgtcaacccctcatgtgaatttt
cgcctggattcccaccccgtgtctccaaaaatgattgtggagcgcccgttaaaccaaaat
ggctacacactggttgtcactgggaagacggtcaccaagatcccactgaacgggctgggc
tgtgaacatttccagtcctgcagccagtgtctctctgcccctccctttgtgcagtgtggc
tggtgccataacaaatgtgtgcgattggaggaatgccccagtggagtatggactcaagac
gtctgtcatcctaccatctacaaggttttccccattagcgcccccctggaaggagggaca
acgctgaccatatgtggctgggactttggattcaggaggaataataaatttgatttaaag
aaaaccagaattctccttggaaatgagagctgcaccttgaccttaagtgagagtacagca
aatacgttaaaatgcacagttggtcctgcaatgagtgagcacctcaatctgtccataatt
atttcaaacggtcgagggtcagcgcaatacactgcattttcttacgtggatcctatcata
acaagtatttctccaagttatggtcctaagactggtggcactttacttactttaactgga
aagtacctaaacagtgggaattctagacacatttcaattggtggaaaaacatgtacttta
aaaagtgtgtcagagagtattctcgaatgttataccccagcccaaaccacttcaactgag
tttcctattaaattgaaaattgatttagccaaccgcgagactaacagcttcagttaccag
gaagaccccattgtcgaacaaattcacccaaccaaatcttttattagtggcgggagcaca
ataacaggtgttggaaaaaacctaaattcagttagtggcctgaggatggtaataaacgtg
catgaagcaggaaggaacttcactgtggcatgtcagcaccgctctaattcggagatcatc
tgctgcacaactccttccctccaacagctgagcctgcagctccccctgagaaccaaagcc
tatttcatgttggacgggatccattccaaatactttgatctcatttatgtacatgatcct
gtgtttaagtttttcgaaaagccagtgctgatctcaataggcaatgaaaatgtcctggaa
attaagggaaatgacattgaccctgaagcagttaaaggtgaagtgttaaaagtgggaaat
aagagctgtgagaaaatacagtcacattcggaagccgtttcatgtaccgtccccagtgac
ctgctcaagctgaacaacgagctaaatatagagtggaagcaagcagtttcttcaactgtc
cttggaaaagtaatagttcaaccagatcaggatttcacaggattgattgttggtgttgtc
tcgatatcagtaatactctcgttattgctcggacttttcctgtggctgaaaaggagaaag
caaattaaagatctgggcagtgaattagttcgctatgatgcacgagtacacactcctcac
ttggataggctcgtaagtgcccgaagtgtaagcccaaccacagaaatggtctcaaatgaa
tctgtagactaccgagctacttttccagaagagcagtttcctaactcgtcccagaatgga
tcctgccgacaagtgcagtaccctctgatggacctctcccccatcctgcctggtggagac
tctgacgtatctagtccattgctgcaaaatacagttcgcattgacctcagcacgctcaat
ccggagctggttcaggccgtccagcatgtggtgatcgggcctagcagcctgattgtgcat
ttcagtgaagtcataggaaggggacattttggttgtgtgtatcatgggactttgttggat
aatgatgacaagaaaattcactgtgctgtgaaatccttgaatagaatcaccgacatagga
gaagtttcccagtttctgactgaagggatcatcatgaaagatttcagtcatcccaatgtt
ctctcgctcttgggaatctgccttcgcagtgaggggtccccactggtggtcctaccttac
atgaagcatggagatcttagaaatttcattagaaatgaaactcataacccaactgtaaaa
gatcttattggctttggtcttcaagtagccaaaggtatgaaataccttgcaagcaaaaag
tttgtgcacagagacttggccgccagaaattgtatgctggatgaaaacttcactgtcaag
gttgctgattttggtcttgccagagacgtgtatgataaagaatactacagtgtccacaac
aaaacaggtgccaagctgccggtgaagtggatggctttggaaagtctgcagactcagaag
ttcaccaccaagtctgatgtgtggtcctttggcgtgctcctctgggaactgatgacaaga
ggcgccccgccttatccagacgttaacacctttgatataacagtttacttgttgcaaggc
agaaggctcttgcaacccgaatactgcccagatcccttgtatgaagtgatgctaaaatgc
tggcaccctaaagccgagttgcgcccatcctttgctgaactggtctccaggatatcagcg
atattctccgctttcatcggggagcactatgtccacgtgaacgctacttatgtgaatgtc
aaatgtgtggctccatacccttgtctgttgtcatcacaagatcatgttgatggtgaggga
gacacatga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (22)   
   KEGG PATHWAY (22)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (22)   
   KEGG ORTHOLOGY (1)   
   RefGene (17)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   ENSEMBLRAPID (1)   
   OC (1)   
Protein sequence (5)   
   UniProt (1)   
   RefSeq(pep) (4)   
DNA sequence (4)   
   RefSeq(nuc) (4)   
Protein domain (8)   
   Pfam (8)   
All databases (66)   

Download RDF
DBGET integrated database retrieval system