KEGG   Heterocephalus glaber (naked mole-rat): 101697634
Entry
101697634         CDS       T02812                                 
Symbol
Atp1a1
Name
(RefSeq) ATPase Na+/K+ transporting subunit alpha 1
  KO
K01539  sodium/potassium-transporting ATPase subunit alpha [EC:7.2.2.13]
Organism
hgl  Heterocephalus glaber (naked mole-rat)
Pathway
hgl04022  cGMP-PKG signaling pathway
hgl04024  cAMP signaling pathway
hgl04260  Cardiac muscle contraction
hgl04261  Adrenergic signaling in cardiomyocytes
hgl04820  Cytoskeleton in muscle cells
hgl04911  Insulin secretion
hgl04918  Thyroid hormone synthesis
hgl04919  Thyroid hormone signaling pathway
hgl04925  Aldosterone synthesis and secretion
hgl04960  Aldosterone-regulated sodium reabsorption
hgl04961  Endocrine and other factor-regulated calcium reabsorption
hgl04964  Proximal tubule bicarbonate reclamation
hgl04970  Salivary secretion
hgl04971  Gastric acid secretion
hgl04972  Pancreatic secretion
hgl04973  Carbohydrate digestion and absorption
hgl04974  Protein digestion and absorption
hgl04976  Bile secretion
hgl04978  Mineral absorption
Brite
KEGG Orthology (KO) [BR:hgl00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04024 cAMP signaling pathway
    101697634 (Atp1a1)
   04022 cGMP-PKG signaling pathway
    101697634 (Atp1a1)
 09140 Cellular Processes
  09142 Cell motility
   04820 Cytoskeleton in muscle cells
    101697634 (Atp1a1)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    101697634 (Atp1a1)
   04918 Thyroid hormone synthesis
    101697634 (Atp1a1)
   04919 Thyroid hormone signaling pathway
    101697634 (Atp1a1)
   04925 Aldosterone synthesis and secretion
    101697634 (Atp1a1)
  09153 Circulatory system
   04260 Cardiac muscle contraction
    101697634 (Atp1a1)
   04261 Adrenergic signaling in cardiomyocytes
    101697634 (Atp1a1)
  09154 Digestive system
   04970 Salivary secretion
    101697634 (Atp1a1)
   04971 Gastric acid secretion
    101697634 (Atp1a1)
   04972 Pancreatic secretion
    101697634 (Atp1a1)
   04976 Bile secretion
    101697634 (Atp1a1)
   04973 Carbohydrate digestion and absorption
    101697634 (Atp1a1)
   04974 Protein digestion and absorption
    101697634 (Atp1a1)
   04978 Mineral absorption
    101697634 (Atp1a1)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    101697634 (Atp1a1)
   04961 Endocrine and other factor-regulated calcium reabsorption
    101697634 (Atp1a1)
   04964 Proximal tubule bicarbonate reclamation
    101697634 (Atp1a1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hgl04147]
    101697634 (Atp1a1)
Enzymes [BR:hgl01000]
 7. Translocases
  7.2  Catalysing the translocation of inorganic cations
   7.2.2  Linked to the hydrolysis of a nucleoside triphosphate
    7.2.2.13  Na+/K+-exchanging ATPase
     101697634 (Atp1a1)
Exosome [BR:hgl04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   101697634 (Atp1a1)
  Exosomal proteins of other body fluids (saliva and urine)
   101697634 (Atp1a1)
  Exosomal proteins of colorectal cancer cells
   101697634 (Atp1a1)
  Exosomal proteins of bladder cancer cells
   101697634 (Atp1a1)
SSDB
Motif
Pfam: E1-E2_ATPase Cation_ATPase_C Cation_ATPase Cation_ATPase_N Hydrolase Hydrolase_3 EssA HAD
Other DBs
NCBI-GeneID: 101697634
NCBI-ProteinID: XP_004853865
UniProt: A0A0P6K1S2
Position
Un
AA seq 1024 aa
MGKGAGRDKYEPAAVSEQDDKKNKKAKKERDMDELKKEVSMDDHKLSLDELHRKYGTDLS
RGLTSARAAEILARDGPNALTPPPTTPEWVKFCRQLFGGFSMLLWIGAVLCFLAYSIETL
SMEEMPSNDNLYLGVVLSAVVIITGCFSYYQEAKSSKIMDSFKNMVPQQALVIRNGEKMS
INAEGVVVGDLVEVKGGDRIPADLRIISANGCKVDNSSLTGESEPQTRSPDFTNDNPLET
RNIAFFSTNCVEGTARGIVVYTGDRTVMGRIATLASGLEGGQTPIAAEIEHFIHIITGVA
VFLGVSFFILSLILEYSWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVK
NLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTENQSGVTFDKTSATWL
ALSRIAGLCNRAVFQANQENVPILKRAVAGDASESALLKCIELCCGSVKEMRDRYAKIVE
IPFNSTNKYQLSIHKNPNTNEPRHLLVMKGAPERILDRCSSILLHGKEQPLDEELKDAFQ
NAYLELGGLGERVLGFCHLLLPDEQFPEGFQFDTDEVNFPLDNLCFVGLISMIDPPRAAV
PDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPVSQVNPRD
AKACVLHGSDLKDMSPEQLDDILKHHTEIVFARTSPQQKLLIVEGCQRQGAIVAVTGDGV
NDSPALKKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYT
LTSNIPEITPFLIFIIANIPLPLGVVTILCIDLGTDMVPAISLAYEQAESDIMKRQPRNP
KTDKLVNERLISMAYGQIGMIQALGGFFAYFVIMAENGFLPIHLLGLRLDWEDRWINDME
DSYGQQWTYEQRKIVEFTCHTAFFVSIVVVQWADLIICKTRRNSVFQQGMKNKILIFGLF
EETALAAFLSYCPGMGVALRMYPLKPSWWFCAFPYSLLIFVYDEVRKLIIRRRPGGWVEK
ETYY
NT seq 3075 nt   +upstreamnt  +downstreamnt
atggggaagggggctggacgtgataaatatgaacccgcagcagtttcagaacaagatgac
aaaaagaacaaaaaggccaagaaagaaagggatatggatgaactgaagaaagaagtttct
atggatgaccataaacttagccttgatgaacttcatcgtaaatatggaacagacttgagc
cgaggcttaacctctgcccgggctgctgagatcctggcccgagatggtcctaatgccctc
acgccccctcccactactccggaatgggtcaaattctgccggcagctgtttgggggcttc
tcgatgttactgtggattggagcagttctttgcttcttggcctatagcattgaaacctta
agcatggaagagatgccatcaaatgataatttatatcttggtgtggtgctgtctgctgtt
gtcatcataactggctgtttctcctactatcaagaagctaaaagttcaaagattatggat
tcctttaaaaacatggtccctcagcaagcccttgtgattcgaaatggtgagaaaatgagc
ataaatgcagaaggtgttgtggtgggggatctggtggaagtcaaaggaggagatcgaatc
cctgctgatctcagaatcatatctgcaaatggctgcaaggtggataactcctccctcact
ggtgaatcggaaccccagactaggtctccggatttcacaaatgataatcccttggagacg
aggaacattgcctttttttcaaccaactgtgtggaaggcactgctcgtggcattgttgtg
tacaccggggaccgcactgtgatgggaagaatcgctaccctggcttctgggctggaagga
ggccagacacccatagctgcagaaatcgaacacttcatccacatcatcacaggtgtggct
gtgttcctgggcgtgtctttcttcattctctctctgatcctggagtacagctggctcgag
gccgtcatcttcctcatcggcattatcgtagccaatgtgccggaaggtctgctggccact
gtcacggtgtgtctcacgcttactgccaaacgcatggcacggaagaactgcttggtgaag
aacttagaagctgtggagacactggggtccacatctaccatctgctcggataagactggc
actctgacgcagaaccgaatgacagtggcccacatgtggtttgacaatcaaatccacgaa
gctgatacgacagagaatcagagtggtgttacattcgacaagacctcagccacctggctt
gctctgtccagaattgcgggtctttgtaacagggcagtgtttcaggctaaccaggaaaac
gtccctattcttaagcgggcagttgcaggcgatgcctctgagtcggcactgttaaaatgc
attgagctgtgttgtggctctgtgaaggagatgagagacagatatgccaagatcgtcgag
ataccattcaactccaccaacaagtatcagttatccattcataagaaccccaacacgaac
gagccccgacacctcctggtgatgaagggtgctccagaaaggatcctggaccgctgcagc
tctatcctcctccatggcaaggagcagcccctggatgaggagctgaaggacgcctttcag
aatgcctacctggagctgggtggcctcggagagcgagtgctgggtttctgccaccttctt
ctgcccgacgaacagttccccgaaggcttccagtttgacactgatgaagtgaatttccct
ctggataatctctgctttgttgggctcatctccatgattgacccgcccagggctgctgtt
cctgatgctgtgggcaaatgccgaagtgctggaattaaggtcattatggtcacgggagac
catccaatcacagcaaaagccattgccaaaggtgtgggcatcatctcagagggcaacgag
actgtagaagacatcgctgcccgcctcaacatcccagtgagccaggttaaccccagagat
gccaaggcctgtgtcttgcatggcagtgatctgaaggacatgagcccggagcagctagat
gacattttgaagcaccacactgagattgtgtttgcaaggacgtccccgcagcagaagctt
cttattgtggaaggctgccagagacagggtgctattgtggccgtcaccggtgatggtgtc
aatgactctccagctttgaagaaagcggacattggggttgctatggggattgctggctcc
gatgtgtctaaacaagccgctgacatgattcttctggatgacaactttgcctcaattgtg
actggagtagaggaaggtcgtctgatctttgataacttgaagaaatccattgcttacacc
ctaaccagtaacattccggagatcacccccttcctgatatttattattgcaaacattcca
ctaccgctaggggttgtcaccatcctctgcatcgacttgggcactgacatggtccctgcc
atctcactggcctatgagcaagctgagagtgacatcatgaagagacagcccagaaacccc
aaaaccgacaagctagtgaatgagcggctgatcagcatggcctatggacagatcggtatg
atccaggccctggggggcttcttcgcttactttgtgattatggctgagaatggcttcctt
ccaattcacctgttggggctccgtttggactgggaagaccggtggatcaatgatatggaa
gacagctatgggcagcagtggacctacgagcagaggaagattgtggagttcacctgccac
acagccttcttcgtcagtattgtggtggtgcagtgggccgacttgatcatctgtaagacc
aggaggaattccgtcttccagcaggggatgaagaacaagatcttaatatttggcctcttt
gaagagacagcccttgctgctttcctttcctactgccctggaatgggtgtcgcccttagg
atgtatcccctcaaaccttcctggtggttctgtgccttcccttactccctgctcatcttc
gtgtatgatgaagtcaggaagctcatcatcaggcggcgccctggcggctgggtggagaag
gaaacctactactag

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (19)   
   KEGG PATHWAY (19)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (34)   
   KEGG ORTHOLOGY (1)   
   RefGene (30)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (3)   
   RefSeq(nuc) (1)   
   GenBank (1)   
   EMBL (1)   
Protein domain (8)   
   Pfam (8)   
All databases (71)   

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