KEGG   Heterocephalus glaber (naked mole-rat): 101698280
Entry
101698280         CDS       T02812                                 
Symbol
Adam10
Name
(RefSeq) ADAM metallopeptidase domain 10
  KO
K06704  disintegrin and metalloproteinase domain-containing protein 10 [EC:3.4.24.81]
Organism
hgl  Heterocephalus glaber (naked mole-rat)
Pathway
hgl04148  Efferocytosis
hgl05010  Alzheimer disease
Brite
KEGG Orthology (KO) [BR:hgl00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    101698280 (Adam10)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    101698280 (Adam10)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:hgl01002]
    101698280 (Adam10)
  09183 Protein families: signaling and cellular processes
   04090 CD molecules [BR:hgl04090]
    101698280 (Adam10)
Enzymes [BR:hgl01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.24  Metalloendopeptidases
    3.4.24.81  ADAM10 endopeptidase
     101698280 (Adam10)
Peptidases and inhibitors [BR:hgl01002]
 Metallo peptidases
  Family M12: astacin/adamalysin family
   101698280 (Adam10)
CD molecules [BR:hgl04090]
 Proteins
  101698280 (Adam10)
SSDB
Motif
Pfam: Reprolysin_2 Reprolysin_5 Reprolysin_3 ADAM10_Cys-rich Reprolysin_4 Disintegrin Reprolysin Pep_M12B_propep Peptidase_M66
Other DBs
NCBI-GeneID: 101698280
NCBI-ProteinID: XP_004855790
UniProt: A0A0N8ETL7
Position
Un
AA seq 748 aa
MVLPRVLILLLSWAAGLGGQYGNPLNKYIRHYEGLSYNVDSLHQKHQRAKRAVSHEDQFL
RLDFHALGRHFNLRMKRDTSLFSDEFKVETSDKVLDYDTSHIYTGHIYGEEGSFSHGSVI
DGRFEGFIRTRGGTFYIEPAERYIKDQVLPFHSVIYHEDDINYPHKYGPQGGCADHSVFE
RMKQYQMTGVEEATQKPQEEHAPNGPELLRKKRTTLAERNTCQLYIQTDHLFYKYYGTRE
AVIAQISSHVKAIDTIYQTTDFSGIRNISFMVKRIRINTTADEKDPSNPFRFPNIGVEKF
LELNSEQNHDDYCLAYVFTDRDFDDGVLGLAWVGAPSGSSGGICEKSKLYSDGKKKSLNT
GIITVQNYGSHVPPKVSHITFAHEVGHNFGSPHDSGTECTPGESKNLGQKENGNYIMYAR
ATSGDKLNNNKFSLCSIRNISQVLEKKRNNCFVESGQPICGNGMVEQGEECDCGYSDQCK
DECCFDANQPVGKKCKLKPGKQCSPSQGPCCTAQCTFKSKSEKCRDDSDCAREGICNGVT
ALCPASDPKPNFTDCNRHTQVCINGQCAGSICEKYDLEECTCASSDGKDDKELCHVCCMK
KMDPSTCASTGSVQWSKHFSGRTITLQPGSPCNDFRGYCDVFMRCRLVDADGPLARLKKA
IFSPQLYENIAEWIVAHWWAVLLMGIALIMLMAGFIKVCSVHTPSSNPKLPPPKPLPGTL
KRRRPPQPIQQPQRQRPRESYQMGHMRR
NT seq 2247 nt   +upstreamnt  +downstreamnt
atggtgttgccgagagtgttaattctgctcctctcctgggcggcggggctgggaggtcag
tatggaaaccctctaaacaaatatattagacattatgaaggattatcttataatgtggat
tcattacaccaaaaacatcagcgtgccaaaagagcagtgtcacacgaggaccagttttta
cgtctagatttccatgcactcggaagacatttcaacctacgaatgaagagggacacttcg
ttgtttagtgatgaatttaaagtagaaacatcagataaagtacttgattatgatacctct
cacatttacactggacatatttatggtgaagaaggaagctttagccatgggtcagtaatt
gatggaagatttgaaggattcatccggactcgtggtggcacattttacattgagcctgca
gagagatacattaaagaccaagttctgccatttcattctgtcatttatcatgaagacgat
attaactatcctcacaaatacggaccccaggggggctgtgcggaccactcagtgtttgaa
aggatgaagcagtaccagatgacgggggtggaagaagcaacacagaaacctcaagaggag
catgctcctaatggtccagaactcctgaggaaaaaacgtacaacgttagctgaaagaaat
acttgtcagctttatattcagactgatcacctcttctataaatactatgggacacgagaa
gctgtgattgcccagatatccagtcatgttaaagcaattgatacaatttaccagaccaca
gacttctccgggatccgaaacatcagtttcatggtgaaacgcataagaatcaatacaact
gctgatgaaaaggacccttcaaatcctttccgtttcccaaatattggcgtggagaagttt
ctggagttgaattctgagcagaatcacgatgactactgtttggcctatgtcttcacagac
cgggactttgatgatggggttcttggtctggcttgggttggagcaccttcaggaagctct
ggcggaatctgtgaaaaaagtaagctctattccgatggtaagaagaagtccttaaacact
ggaattattaccgtccagaactatggatctcatgtccctcccaaagtctctcacataact
tttgctcatgaagttggacataactttggatctccacatgattctggaacagagtgcaca
ccaggagaatctaagaatttaggacaaaaagaaaatggcaattacatcatgtatgcgaga
gcaacatctggggacaaacttaacaacaataaattctcactctgtagtattagaaatata
agccaagttcttgagaagaagagaaacaactgttttgttgagtccggccagcccatctgc
gggaatgggatggtggagcagggagaggagtgtgactgcggctacagcgaccaatgcaag
gacgagtgctgcttcgatgccaaccagccggtggggaagaagtgcaagctgaagcctgga
aagcagtgcagtccaagccaaggtccctgctgtacggcacagtgtacattcaagtccaag
tctgagaagtgtcgggacgattccgattgtgcgagagaagggatatgtaacggcgtcaca
gctctgtgcccggcgtctgatcctaaaccaaactttacagactgtaacaggcatacacaa
gtgtgcattaatgggcaatgtgcaggctccatctgtgagaagtacgacttggaggagtgt
acctgtgccagttctgatggcaaagatgacaaagagttatgccatgtctgctgcatgaag
aaaatggacccttcaacctgtgccagcacagggtctgtgcagtggagcaagcatttcagc
ggtcgcaccatcaccctgcagcctgggtctccttgcaatgatttcagaggctactgtgat
gttttcatgcggtgtagattagtggatgctgatggtcctctagctaggcttaaaaaagca
atttttagtccacaactctatgaaaacattgctgaatggattgtggcgcattggtgggca
gtgttgctcatggggatcgccctgatcatgctgatggcggggttcatcaaggtgtgcagc
gtccacactcctagcagtaacccaaagttgcctcctcctaaaccacttccaggcacttta
aagaggaggagacctccacagcccattcagcagccccagcgccagaggccgcgggagagt
taccagatgggacacatgagacgctaa

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Ontology (4)   
   KEGG BRITE (4)   
Pathway (2)   
   KEGG PATHWAY (2)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (15)   
   KEGG ORTHOLOGY (1)   
   RefGene (11)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   RefSeq(pep) (2)   
DNA sequence (4)   
   RefSeq(nuc) (2)   
   GenBank (1)   
   EMBL (1)   
Protein domain (9)   
   Pfam (9)   
All databases (39)   

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