KEGG   Heterocephalus glaber (naked mole-rat): 101710362
Entry
101710362         CDS       T02812                                 
Symbol
Usp8
Name
(RefSeq) ubiquitin specific peptidase 8
  KO
K11839  ubiquitin carboxyl-terminal hydrolase 8 [EC:3.4.19.12]
Organism
hgl  Heterocephalus glaber (naked mole-rat)
Pathway
hgl04137  Mitophagy - animal
hgl04144  Endocytosis
hgl04934  Cushing syndrome
Brite
KEGG Orthology (KO) [BR:hgl00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    101710362 (Usp8)
   04137 Mitophagy - animal
    101710362 (Usp8)
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    101710362 (Usp8)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:hgl01002]
    101710362 (Usp8)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hgl04131]
    101710362 (Usp8)
   04121 Ubiquitin system [BR:hgl04121]
    101710362 (Usp8)
Enzymes [BR:hgl01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.19  Omega peptidases
    3.4.19.12  ubiquitinyl hydrolase 1
     101710362 (Usp8)
Peptidases and inhibitors [BR:hgl01002]
 Cysteine peptidases
  Family C19: ubiquitin-specific protease family
   101710362 (Usp8)
Membrane trafficking [BR:hgl04131]
 Endosome - Lysosome transport
  Others
   Others
    101710362 (Usp8)
Ubiquitin system [BR:hgl04121]
 Deubiquitinating enzyme (DUB)
  Ubiquitin-specific proteases (UBPs)
   UBP/USP
    101710362 (Usp8)
SSDB
Motif
Pfam: UCH USP8_dimer WW_USP8 UCH_1 Rhodanese Metallothio_Pro HscB_4_cys
Other DBs
NCBI-GeneID: 101710362
NCBI-ProteinID: XP_004835477
Position
Un
AA seq 1084 aa
MPAVASVPKELYLSSSLKDLNKKTEVKPEKISTKNYVHSALKIFKAAEECRLDRDEERAY
VLYMKYVTVYNLIKKRPDFKQQQDYFHSILGPANIKKAIEEAERLSESLKLRYEEAEVRK
KLEEKDRQEEEQFQQQKRQEAGREDGSAAAKGSLENVLDSKNKSQKINGEKSEKKETAEK
GAVTAKELYTMMTDKNITLMIMDTRRMQDYRDSCIADSVCVPEEAISPGVTATWIEANLP
EDSKDTWKKRGNVDYVVLLDWFSSAKDLQLGTTLQSLKDALFKWESKTVLRHEPLVLEGG
YENWLLCYPQYTTNAKITPPPRGRSEEVSVSLDFTYPSLEESVPSKPPAQMPPPHPEVNE
NTELTGDEGELSALMPAEPVAASRADVSPTVQPVPIIKNVPQIDRSKKPAVRLPEDHRVK
SESTDHEQQQSPQNGKAIPDRSTKPAFPPAAAVFSDEEKARIHAEASLLMEKSKQEKGLR
GRQPEEQKEKLSGDEQEQKARKKQEAEESEIPESQEKAKEMEKRESEQAKKEDKETSAKR
GKETTGLKRQSKSEHETSDAKKSVEDRGKRCPTPEVQRKPVGDTSVSVAGDASAGKAQRE
PLTRARSEEMGRIVPGLPSGWAKFLDPITGTFRYYHSPTNTVHMYPPEMAPSSAPPSIPP
THKAKPQVPAEWDKDPSKLKRSYSSPDITQSVPEDGRRKPAVTPAVNRENKPTCCPKAEI
SRLSASQIRNLNPVFGGSGPALTGLRNLGNTCYMNSILQCLCNAPHLADYFNRNYYQDDI
NRSNLLGHKGEVAEEFGIIMKALWTGQYRYISPKDFKITIGKINDQFAGYSQQDSQELLL
FLMDGLHEDLNKADNRKRHKEENNDHLDDFKAAEHAWQKHKQLNESIIVALFQGQFKSTV
QCLTCHRKSRTFEAFMYLSLPLASTSKCTLQDCLRLFSKEEKLTDNNRFYCSHCRARRDS
LKKIEIWKLPPVLLVHLKRFSYDGRWKQKLQTSVDFPLENLDLSQYVIGPKHSLKKYSLF
SVSNHYGGLDGGHYTAYCKNAARQRWFKFDDHEVSDISVSSVKSSAAYILFYSSLGPRAA
DVTT
NT seq 3255 nt   +upstreamnt  +downstreamnt
atgcctgctgtggcttcagttcctaaagaactctatctcagttcttcgctaaaagacctc
aataagaagacagaagttaagccagagaaaatcagcactaagaattatgtgcacagtgct
ctgaagatcttcaaggcagcagaagaatgcagattagaccgcgatgaggaaagggcttat
gtactgtatatgaaatatgtgactgtttataaccttatcaaaaagagacctgatttcaag
caacagcaggactactttcattcaatactcggacctgcaaacatcaaaaaagctattgaa
gaagctgaaagactctctgaaagccttaaactgagatatgaagaagctgaagttcggaaa
aagctcgaagagaaggacagacaggaagaggagcagttccagcagcagaagcggcaggaa
gcaggaagagaggacggcagtgcagcagctaaaggttctctggagaatgtattggattcc
aaaaacaaatcccaaaagatcaatggtgaaaagagtgaaaaaaaagaaactgcagagaaa
ggagcagtcacagcaaaggaactgtacacaatgatgacagataaaaacatcaccctgatg
ataatggacacacgaagaatgcaggattaccgggattcctgtattgcagattctgtctgt
gtcccggaagaggccatcagtccaggagtcactgctacttggattgaagcaaacctccca
gaggattctaaagacacatggaagaagagggggaatgtggattatgtggtacttcttgac
tggtttagttctgcaaaagatttacagcttggaacaactctacagagtctgaaagatgca
cttttcaagtgggaaagtaaaactgtcctgcgccatgagcccttggttttggagggaggc
tatgaaaactggcttctgtgctatccccagtacacaacaaatgctaagatcactccaccc
ccacgaggcaggagcgaagaggtgtctgtctcattggatttcacttatccctcactggaa
gaatcagttccttccaaacctcctgctcagatgccaccgcctcatccagaagtaaatgaa
aacacagaattgacaggtgatgaaggagaactgagtgcattaatgccagctgaaccagtt
gctgcttccagagctgatgtttcacctacagttcagccagtgcctattataaagaatgtt
ccgcagattgatcgtagtaaaaaaccagcagtcagattgcccgaagatcatagagtaaaa
tctgagagtacagaccatgagcagcagcagtctcctcagaatggaaaagccattcccgac
cgctccaccaagccagcgtttccccctgcagctgctgtgttttcggatgaagagaaagcc
cggattcatgcagaagcctctttgctcatggagaaaagcaagcaagaaaaaggacttcga
ggaaggcagcccgaggaacagaaagagaagctaagcggggacgaacaagaacaaaaagcc
agaaagaaacaagaagctgaagaaagtgaaatcccagaaagtcaagaaaaagcaaaagaa
atggagaagagagaaagtgaacaagccaagaaggaagataaggaaacttcagcaaagagg
ggcaaagaaacaacaggattaaaaagacagagtaaaagcgaacatgaaacttctgatgcc
aagaagtctgtggaagacagggggaaaaggtgtccaactccagaagtgcagagaaagcca
gtaggagacacctctgtgtctgtggcgggagatgcaagtgcaggcaaggctcaaagggag
cctttgacgagagcacggagcgaagaaatggggaggatcgtcccaggactgccttccggt
tgggccaagtttctggacccgatcactggaaccttccgttattatcattcacccaccaac
actgtccatatgtacccaccagaaatggctccttcctctgctcctccttccatccccccg
actcacaaagccaagccccaggttcctgccgagtgggacaaggacccctccaaactgaag
cgctcctactcctccccagacatcacccagtctgtgccagaggacgggaggaggaagccc
gcagtaacaccagctgtgaatcgggagaacaagccaacatgctgccccaaagccgagatc
tccaggctctctgcctctcagatccgaaacctcaatcctgtcttcggagggtctggacca
gccctcactggacttcggaacttaggaaatacgtgctacatgaactccatcctgcagtgc
ctgtgcaatgcaccgcacctggctgattatttcaaccggaactattatcaggatgatatt
aacaggtcaaatttgttggggcataaaggagaagtggcagaagagttcggtataatcatg
aaagcgctatggacaggtcagtataggtacatcagtccaaaagactttaaaatcaccatc
gggaagatcaatgaccagttcgcaggatacagccagcaagattcacaagagctgctcctc
ttcctcatggatggtctccatgaggacctaaataaagctgacaaccggaagagacataaa
gaagagaacaatgatcacctcgatgacttcaaagctgcagaacatgcttggcagaaacat
aagcagctcaatgaatctattatcgttgcactctttcagggtcagttcaaatccacagta
cagtgcctcacttgtcacagaaagtccaggacatttgaggccttcatgtatttgtctctg
ccactagcatccacaagtaaatgtacactacaggattgccttagattattttccaaggaa
gaaaaactcacagataacaataggttttactgcagtcactgcagagctcggcgggattct
ctcaaaaagatagaaatctggaagttgccacctgtgcttctggtgcatctgaaacgtttt
tcctacgatggcagatggaagcagaaattacaaacatccgtggacttcccactagaaaat
cttgatttgtcacagtatgttattggtccaaagcacagcctgaagaagtacagcctgttt
tctgtttcaaatcactacggcgggctggacggaggccactacactgcttactgtaaaaac
gcagccagacagcggtggtttaagtttgatgatcacgaagtttctgatatctctgtttct
tctgtgaagtcatcagcagcgtatattctcttttattcttcactgggaccacgagcagct
gatgtaaccacataa

  All links  
Ontology (5)   
   KEGG BRITE (5)   
Pathway (3)   
   KEGG PATHWAY (3)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (26)   
   KEGG ORTHOLOGY (1)   
   RefGene (22)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (7)   
   Pfam (7)   
All databases (45)   

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