KEGG   Heterocephalus glaber (naked mole rat): 101711512Help
Entry
101711512         CDS       T02812                                 

Gene name
Ep300
Definition
E1A binding protein p300
Orthology
K04498  
E1A/CREB-binding protein [EC:2.3.1.48]
Organism
hgl  Heterocephalus glaber (naked mole rat)
Pathway
HIF-1 signaling pathway
FoxO signaling pathway
Cell cycle
Wnt signaling pathway
Notch signaling pathway
TGF-beta signaling pathway
Adherens junction
Jak-STAT signaling pathway
Long-term potentiation
Melanogenesis
Thyroid hormone signaling pathway
Huntington's disease
Tuberculosis
Hepatitis B
Influenza A
HTLV-I infection
Herpes simplex infection
Epstein-Barr virus infection
Pathways in cancer
Viral carcinogenesis
MicroRNAs in cancer
Renal cell carcinoma
Prostate cancer
Brite
KEGG Orthology (KO) [BR:hgl00001]
 Environmental Information Processing
  Signal transduction
   04310 Wnt signaling pathway
    101711512 (Ep300)
   04330 Notch signaling pathway
    101711512 (Ep300)
   04350 TGF-beta signaling pathway
    101711512 (Ep300)
   04630 Jak-STAT signaling pathway
    101711512 (Ep300)
   04066 HIF-1 signaling pathway
    101711512 (Ep300)
   04068 FoxO signaling pathway
    101711512 (Ep300)
 Cellular Processes
  Cell growth and death
   04110 Cell cycle
    101711512 (Ep300)
  Cell communication
   04520 Adherens junction
    101711512 (Ep300)
 Organismal Systems
  Endocrine system
   04919 Thyroid hormone signaling pathway
    101711512 (Ep300)
   04916 Melanogenesis
    101711512 (Ep300)
  Nervous system
   04720 Long-term potentiation
    101711512 (Ep300)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    101711512 (Ep300)
   05206 MicroRNAs in cancer
    101711512 (Ep300)
   05203 Viral carcinogenesis
    101711512 (Ep300)
   05211 Renal cell carcinoma
    101711512 (Ep300)
   05215 Prostate cancer
    101711512 (Ep300)
  Neurodegenerative diseases
   05016 Huntington's disease
    101711512 (Ep300)
  Infectious diseases
   05152 Tuberculosis
    101711512 (Ep300)
   05166 HTLV-I infection
    101711512 (Ep300)
   05164 Influenza A
    101711512 (Ep300)
   05161 Hepatitis B
    101711512 (Ep300)
   05168 Herpes simplex infection
    101711512 (Ep300)
   05169 Epstein-Barr virus infection
    101711512 (Ep300)
Enzymes [BR:hgl01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.48  histone acetyltransferase
     101711512 (Ep300)
Transcription factors [BR:hgl03000]
 Eukaryotic Type
  Other transcription factors
   Pocket domain CBP
    101711512 (Ep300)
Mitochondrial biogenesis [BR:hgl03029]
 Mitochondrial quality control factors
  Regulator of mitochondrial biogenesis
   Coactivators
    101711512 (Ep300)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Position
Un
AA seq 2420 aa AA seqDB search
MAENVVEPGPPSAKRPKLSSPALSASASDGTDFGSLFDLEHDLPDELINSTELGLTNGGD
ISQLQTSLGMVQDAASKHKQLSELLRSGSSPNLNMGVGGPGQVMASQAQQNSPGLGLINS
MVKSPMAQAGLTSPSMGMGTSGPNQGPTQSTTGMMSSPVNQPAMGMSPGMNAGINPGMLA
AGNGQGLMPGQVMNGSIGAGRGRPNMQYSNPSMGNAGNLLTEPLQQGSPQMGGQTGLRGP
QPLKMGIMNNPNPYGSPYAQNSGQQIGASGLGLQIQAKPALPNSLSPFPMDKKVVPGGGM
PNMGQQPAPQVQQPGLVTPVTQGMGSGAHTADPEKRKLIQQQLVLLLHAHKCQRREQANG
EVRQCNLPHCRTMKNVLNHMTHCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKN
AGDKRNQQSILTGAPVGLGNPSSLGVGQQSTPSLSTVSQIDPSSIERAYAALGLTYSGNQ
MQPQPQVQAKNQQNQQSGQSPQGIRPMNSMSASPMGVNGGVGVQTPNLLSDSMLHSAINS
QSPMMNENASVASLGPMPTAAQPSSTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAA
LKDRRMENLVAYARKVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNMMP
NAAGMVPVSMNPGPNMGQPQPGIASNGPLPDPAMIRGSVPNQIMPRITPQPGLNQFGPMS
MPQPPIGPRQTSPLQHHGQLAQPGALNPPMGYGPRMQQPSSQSQFLSQTQFPSQGMNVTN
MPLAPSSGQASVSQAQMSSSSCPVNSPVMPPGSQGSHIHCPPLPQQALHQNSPSPVPSRT
PTPHHTPPSIGAQQPPTTAIPAPVPTPPAIPPRPQSQGLHPPSSQTPTPPTTQLPPQVQP
PLPAAPSADQAQQQPRSQQSTAASIPTPTAPLLPPQPTTPLSQPTVSIEGQVSNPPSTSS
TEVNSQTIPEKQPSQEVKMDIKMEVDHPETADAQPEDIQEAKAEECKVEPTETEERSTEL
KPEIKEEEDQPSTSATQSSPAPGQSKKKIFKPEELRQALMPTLEALYRQDPESLPFRQPV
DPQLLGIPDYFDIVKSPMDLSTIKRKLDTGQYQEPWQYVDDIWLMFNNAWLYNRKTSRVY
KYCSKLSEVFEQEIDPVMQSLGYCCGRKLEFSPQTLCCYGKQLCTIPRDATYYSYQNRYH
FCEKCFNEIQGESVSLGDDPSQPQTTINKEQFSKRKNDTLDPELFVECTECGRKMHQICV
LHHEIIWPAGFICDGCLKKTARTRKENKFSAKRLPSTRLGTFLENRVNDFLRRQNHPESG
EVTVRVVHASDKTVEVKPGMKARFVDSGEMAESFPYRTKALFAFEEIDGVDLCFFGMHVQ
EYGSDCPPPNQRRVYISYLDSVHFFRPKCLRTAVYHEILIGYLEYVKKLGYTTGHIWACP
PSEGDDYIFHCHPPDQKIPKPKRLQEWYKKMLDKAVSERIVHDYKDIFKQATEDRLTSAK
ELPYFEGDFWPNVLEESIKELEQEEEERKREENTSNESTDVTKGDSKNAKKKNNKKTSKN
KSSLSRGNKKKPGMPNVSNDLSQKLYATMEKHKEVFFVIRLIAGPAANSLPPIVDPDPLI
PCDLMDGRDAFLTLARDKHLEFSSLRRAQWSTMCMLVELHTQSQDRFVYTCNECKHHVET
RWHCTVCEDYDLCITCYNTKNHDHKMEKLGLGLDDESNNQQAAATQSPGDSRRLSIQRCI
QSLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPICKQLIALCCYHAKHCQEN
KCPVPFCLNIKQKLRQQQLQHRLQQAQMLRRRMASMQRTGVVGQQQGLPSPTPATPTTPT
GQQPATPQTPQPQPTSQPQPTPPNSMPPYLPRTQTAGPVSQGKAAGQVTPPTPPQTAQPS
LPGPPPAAVEMAMQIQRAAETQRQMAQVQIFQRPIQHQMPQMTPMAPMGMNPPPMTRGPS
GHLEPGMGPTAMQQQPPWAQGGLPQPQQLQSGMPRPTMMSVSQHGQPLNIAPQPGLGQVG
VSPLKPGTVSQQALQNLLRTLRSPSSPLQQQQVLSILHANPQLLAAFIKQRAAKYANSNP
QPLTGQPGMAQGQPGLQPPAMPGQQGVHSSPGMQNMNPMQAGVQRAGLAQQQPQQPLQPP
MGGMSPQAQPMNMNHGSMSSQFRDMLRQQQMMRQQQQQGAGPGIGPGMANHNQFQQPQGV
SYPPQQQQQQRMQHHMQQIQQGNMGQMGQLPPALGAEAGASLQAYQQRLLQQQMGSPGQP
NPMSPQQHMLPNQAQSPHLQGQQIPNSLSNQVRSPQPVPSPRPQSQPPHSSPSPRMQPQP
SPHHVSPQTSSPHPGLVAAQAANPMEQGHFASPDQNPMLSQLASHPGMANLHGASATDLG
LSTDNSDLNSNLSQSTLDIH
NT seq 7263 nt NT seq  +upstreamnt  +downstreamnt
atggccgagaatgtggtggaaccggggccgccttcagccaagcggcctaaactctcgtct
ccggccctctcggcgtcggccagcgacggcacagattttggctctttgttcgacctggag
catgacttaccagatgaattaatcaactctacagaattgggactgaccaatggtggtgat
attagtcagcttcagacaagtcttggcatggtacaagatgcagcctctaaacataaacag
ctatcagaattgctacggtctgggagttcccctaacctcaatatgggggttggtggccca
ggccaagttatggccagccaggcccaacagaatagtcctggattaggtctgataaacagc
atggtcaaaagcccaatggcgcaggcaggattgacttctcccagcatggggatgggcact
agtggaccaaatcagggtcccacgcagtccacaacaggtatgatgagcagccccgtaaat
cagcccgccatgggaatgagcccagggatgaatgctggcataaaccctggaatgttggct
gcaggcaatggacaggggctaatgccaggccaagtcatgaatggttcgattggagcaggc
cgaggacgaccaaatatgcagtattcaaacccaagcatgggaaatgctggcaacttattg
acagagccactgcagcagggctcaccccagatgggaggacagacaggactgagaggccct
cagcctcttaagatgggaataatgaacaaccccaacccttatggatcaccttatgctcag
aattctggacagcagattggagccagtggccttggtctccagattcaggcaaagcctgca
ctaccaaatagcttatctccatttccaatggacaaaaaggtggttcctggtgggggaatg
cccaacatgggccaacaacctgccccacaggtccagcagccaggcctggtgactccagtc
acccaggggatgggttctggagcacacacagctgatccggagaagcgcaagctcattcag
cagcagcttgttctccttctgcacgctcacaagtgccagcgccgggagcaggctaatggg
gaggtgaggcagtgcaaccttcctcactgccgtacaatgaagaatgtcctgaaccacatg
acgcactgccagtcaggcaagtcctgccaagtggcacattgtgcatcttctcgacaaatc
atttcacactggaagaactgtacaaggcatgattgtcctgtatgtctcccgctcaaaaat
gctggggataagagaaatcaacagtcgattttgactggagcaccagttgggcttggaaac
cccagctctctaggggtgggtcaacagtctacccctagcctcagcactgttagtcagatt
gatcccagctcaatagaaagagcctatgcagctcttggactgacctattcaggaaaccag
atgcagcctcaaccccaggtgcaggcgaagaaccagcagaatcagcaatctgggcagtct
ccccaaggcatccggcccatgaacagcatgagtgctagtcctatgggagtaaacggtggt
gtaggggttcaaacaccgaatcttctttctgactcaatgttgcattcagccataaattct
caaagcccaatgatgaatgaaaatgccagtgttgcctccctgggccctatgccaacagca
gctcagccatccagtactggaattaggaaacagtggcatgaagatattactcaggatctt
cgaaatcatcttgttcacaaacttgttcaagccatatttcctactccggaccctgctgca
ttaaaagacagacggatggaaaacctggttgcctatgctcgcaaagtggaaggggacatg
tatgaatctgcaaataatcgagcggaatactaccaccttctagctgagaagatctataag
atccagaaagaattagaagaaaaacgaaggaccagactacagaaacagaacatgatgcca
aatgctgcaggcatggtaccggtttctatgaatccagggcctaacatgggacagccacaa
ccaggaatagcttctaatggtcctctgcctgatccagctatgatccgtggcagtgtgcca
aaccagataatgcctcggataactccacaacctggtttgaatcagtttggcccgatgagt
atgccccagccacccattggcccccggcaaacctctcctcttcagcaccatggacagtta
gctcagcctggtgctctcaatccgcctatgggctatggccctcgcatgcagcagccttcc
agccagagccagttcctctcccagactcagttcccgtcacagggaatgaatgtaacaaac
atgcctttggctccatccagcggtcaagcatcagtgtctcaagcacaaatgtccagctct
tcctgcccagtgaactctcctgtcatgcctccagggtctcaggggagccacattcactgt
ccccctctccctcaacaagctctgcatcagaactcaccctctcccgtacctagtcggacc
cccaccccccaccacactcccccaagcataggggctcagcagccaccgacaacagcaatt
ccagcccctgttcccacacctcctgccataccacccaggccacagtcccagggtctacat
ccaccctccagtcagacacccaccccgcctacaacacagcttcctccccaagtgcagcct
ccacttcctgctgctccttcagctgaccaggcacagcagcagcctcgctcacagcagagt
acagcagcctccattcccactccaacggcaccactgctgcctccacagcctacgactccg
ctttcccagcctacagtgagcattgaaggacaggtatcaaaccctccatctacaagtagc
acagaagtgaattctcagacaattcctgagaagcagccttcacaggaagtgaaaatggac
attaaaatggaagtggatcacccagaaacagcagatgcgcagccagaggatattcaggag
gctaaagcagaggaatgtaaagtggagcccacagaaacagaagagagaagtacagagtta
aaacctgaaataaaagaggaggaagaccagccaagtacttctgctacccagtcttctcca
gctccaggacagtcaaagaaaaaaatttttaaaccagaagaattacgacaggccctgatg
ccaaccctggaggcactttaccggcaggacccagaatcccttccctttcgtcagcctgtg
gaccctcagcttctaggaatccctgattatttcgatattgtgaagagccccatggacctt
tctactatcaagaggaagttagacactggacagtatcaagaaccctggcaatacgtggat
gacatttggcttatgttcaacaatgcctggttatataaccggaaaacatcgcgggtatac
aaatactgctccaagctatctgaggtctttgaacaagaaattgatccagtcatgcaaagc
cttggatattgttgtggcagaaagttggagttttctccacagacactgtgttgctatggc
aaacagttatgcacaatccctcgtgatgccacttactacagttaccagaacaggtatcat
ttctgtgagaagtgtttcaatgaaatccaaggggagagcgtttctttgggggatgaccct
tcccagcctcaaactacaataaataaggaacagttttccaagagaaaaaatgacacactg
gatcctgaattgtttgttgaatgcactgagtgtggaagaaagatgcatcagatctgtgtc
cttcatcatgagatcatctggccagctggatttatctgtgatggatgcttgaagaaaact
gcacgaaccaggaaagaaaataagttttctgctaaaaggttgccatctaccagacttggc
acctttctggagaatcgtgtgaatgactttctgaggcgacaaaatcaccctgaatcagga
gaggtcactgtcagggttgttcatgcttctgacaaaactgtggaagtcaaaccaggcatg
aaagcaaggtttgtagatagtggagaaatggcagaatcctttccataccgaaccaaagct
ctctttgccttcgaagaaattgatggtgttgacttgtgcttctttggcatgcacgttcaa
gagtatggctctgactgccctccacccaaccagaggagagtatatatatcttacctcgat
agtgttcatttcttccgtcctaagtgcttgaggactgcagtgtatcatgaaattctaatt
ggatatttagaatatgtcaagaaattaggatatacaacagggcatatttgggcatgtcca
ccaagtgagggggatgattatatcttccattgccatcctcctgaccagaagatacccaag
cccaagcgactgcaagaatggtacaaaaagatgcttgacaaggctgtgtcagaacggatt
gtacatgactacaaggatatttttaaacaagctactgaagatcgattaacaagtgcaaag
gaattgccatactttgagggtgatttctggcccaatgttctggaagagagcattaaggaa
ctggaacaggaggaggaagagagaaaacgagaagagaataccagcaatgaaagcactgat
gtgacaaagggagacagcaaaaatgccaaaaagaagaataataagaaaaccagcaaaaat
aagagcagcctgagtaggggtaacaagaagaagccaggcatgcccaatgtgtctaatgac
ctctcacagaaactctacgccaccatggagaaacacaaagaggtcttctttgtgatccgc
ctcattgctggccctgctgccaactctctgcctcccattgttgatccagaccctcttatc
ccctgtgatctgatggatgggcgggatgcattcctcacccttgcaagggacaagcacctg
gagttctcttcattgaggcgagcccagtggtccaccatgtgcatgcttgtggagctgcac
acgcagagccaggaccgctttgtctacacctgcaatgagtgcaagcaccatgtggagaca
cgctggcactgcactgtctgtgaggattatgacttgtgtatcacgtgctataacactaaa
aaccatgaccacaagatggagaaattgggtcttggcttagatgatgagagcaacaaccaa
caggctgcggccacccagagcccaggagattctcgccgcctgagcatccagcgctgcatc
cagtccctggtccatgcctgtcagtgccgcaatgccaactgctccctgccctcttgccaa
aagatgaaacgagttgtacagcacaccaagggctgcaaacggaaaaccaatggcgggtgc
cccatctgcaagcagctgattgctctctgctgttaccatgccaagcactgccaggagaac
aagtgccctgtgccattctgcctcaacatcaagcaaaagctccgccaacagcagctacag
cacaggctccagcaggcccagatgctgcgcaggaggatggccagcatgcagcgcactggt
gtggtggggcagcaacagggcctgccctccccaactcctgccactccaaccacaccaacg
ggccaacagccagcaaccccgcagacaccccagccccagcctacctctcagccccagccc
acccctcccaacagcatgccaccctacttgcccaggactcaaactgctggcccagtgtcc
cagggtaaggcagcaggccaggtgacccctccaactcctcctcagactgcacagccatct
cttccagggcctccacctgctgcagtagaaatggcaatgcagattcagagagcagctgag
acacagcgccagatggcccaggtgcaaattttccaaaggccaatccagcaccagatgccc
cagatgactcccatggcccccatgggtatgaacccacctcccatgaccagaggccccagt
gggcatctagagccagggatggggccaacagcaatgcaacagcagcccccctgggcccaa
ggaggactgcctcaaccccagcaactccagtctgggatgccaaggccaaccatgatgtca
gtgtcccaacacgggcagcctttgaacatagctccgcagccagggttgggccaggtaggt
gtgagcccactcaaaccaggcactgtgtctcaacaagccttacaaaacctccttcggact
ctcaggtctcccagctctcccctacagcagcaacaggtgcttagtatccttcacgccaac
cctcagctgttggctgcattcataaaacaacgggctgccaaatacgccaactctaatcca
cagcctctcactggacagcctggcatggcccagggacagccagggctgcagccaccagcc
atgccaggtcagcagggcgtccactccagtccaggcatgcagaacatgaatcccatgcag
gcaggtgtgcagagggctggtctggcccagcagcagcctcagcagccactccagccaccc
atgggagggatgagcccccaggcacagccaatgaacatgaatcatggcagcatgtcttcc
cagttccgggacatgttgagacaacagcagatgatgcgacaacagcagcagcagggagca
gggccaggaataggccctggaatggccaaccacaaccagttccagcaaccccagggagtt
agttaccccccacagcagcagcagcagcagcggatgcagcatcacatgcagcagatacaa
caagggaacatgggacagatggggcagcttcccccggccttgggagcagaggcaggagcc
agtctacaggcctatcagcagcgactcctccagcagcagatggggtcccctggtcagccc
aaccccatgagcccccagcagcacatgctcccaaaccaggcccagtccccgcacctccaa
ggccagcagatcccaaattctctctccaatcaagtgcgttctccccagcctgtcccttct
ccacggccacagtcccagcccccccactccagcccatccccaaggatgcagcctcagcct
tctccacaccacgtttccccacaaaccagttccccacatcccggactggttgctgcccag
gccgccaaccccatggaacaagggcattttgccagcccagaccagaatccgatgctctct
cagctcgctagccatccaggcatggcaaacctccatggtgcaagtgccacggacctggga
ctcagcaccgataactcagacttgaattcaaacctctcacagagtacactagacatacac
tag

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