KEGG   Heterocephalus glaber (naked mole rat): 101713955Help
Entry
101713955         CDS       T02812                                 

Gene name
Ugt2a1
Definition
(RefSeq) UDP-glucuronosyltransferase 2A1
  KO
K00699  glucuronosyltransferase [EC:2.4.1.17]
Organism
hgl  Heterocephalus glaber (naked mole rat)
Pathway
hgl00040  Pentose and glucuronate interconversions
hgl00053  Ascorbate and aldarate metabolism
hgl00140  Steroid hormone biosynthesis
hgl00830  Retinol metabolism
hgl00860  Porphyrin and chlorophyll metabolism
hgl00980  Metabolism of xenobiotics by cytochrome P450
hgl00982  Drug metabolism - cytochrome P450
hgl00983  Drug metabolism - other enzymes
hgl01100  Metabolic pathways
hgl05204  Chemical carcinogenesis
Module
hgl_M00014  Glucuronate pathway (uronate pathway)
hgl_M00129  Ascorbate biosynthesis, animals, glucose-1P => ascorbate
Brite
KEGG Orthology (KO) [BR:hgl00001]
 Metabolism
  Carbohydrate metabolism
   00040 Pentose and glucuronate interconversions
    101713955 (Ugt2a1)
   00053 Ascorbate and aldarate metabolism
    101713955 (Ugt2a1)
  Lipid metabolism
   00140 Steroid hormone biosynthesis
    101713955 (Ugt2a1)
  Metabolism of cofactors and vitamins
   00830 Retinol metabolism
    101713955 (Ugt2a1)
   00860 Porphyrin and chlorophyll metabolism
    101713955 (Ugt2a1)
  Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    101713955 (Ugt2a1)
   00982 Drug metabolism - cytochrome P450
    101713955 (Ugt2a1)
   00983 Drug metabolism - other enzymes
    101713955 (Ugt2a1)
 Human Diseases
  Cancers
   05204 Chemical carcinogenesis
    101713955 (Ugt2a1)
Enzymes [BR:hgl01000]
 2. Transferases
  2.4  Glycosyltransferases
   2.4.1  Hexosyltransferases
    2.4.1.17  glucuronosyltransferase
     101713955 (Ugt2a1)
Glycosyltransferases [BR:hgl01003]
 Others
  Hydrophobic molecule
   101713955 (Ugt2a1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: UDPGT Glyco_tran_28_C Pro_3_hydrox_C
Motif
Other DBs
NCBI-GeneID: 101713955
NCBI-ProteinID: XP_004871778
Position
Un
AA seq 527 aa AA seqDB search
MLSNILLLSLQISLLGTTLGGNILIWPMEGSHWLNVKIIIDELIKKEHNVTVLVASGALF
ITPSSYPSLTFEIYKVSFGKERVERVIKDFVLTWLENRPSPSTIWRFYQEMAKVIKDFHM
VSREICDGVLKNEMLMEKLKKGKFEVLVSDPVFPCGDIVALKLGIPFIYSLRFSPASNVE
KHCGKVPYPPSYVPAILSELTDQMTFADRVRNFISYHLQDYMFETLWKPWDSYYSKALGK
PTTLCETMSKAEIWLIRTYWDFEFPRPFLPNFEFVGGLHCKPAKPLPKEMEEFVQSSGED
GIVVFSLGSMVKNLTEEKANLIASALSQIPQKVLWRYKGKKPAMLGPNTQLFDWIPQNDL
LGHPKTKAFITHGGTNGIYEAIYHGIPMVGVPMFADQPDNIAHMKAKGAAVEVNMNTMTS
ADLLNALRIVINDPSYKENAMRLSRIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRVAAHD
LSWFQYHSLDVIGFLLGCVASVVFLVTKCCLFSYQKFIRKGKRIKKE
NT seq 1584 nt NT seq  +upstreamnt  +downstreamnt
atgttaagcaacattctgctgttgtctcttcagataagcctcctaggaaccactcttggt
gggaacatcctgatttggccaatggaaggtagtcactggctcaatgttaagatcattata
gatgagctcattaaaaaagagcataatgtgactgtcctggttgcctctggtgcacttttc
atcacaccatcttcttacccgtctctgacatttgaaatatataaagtgtcctttggaaaa
gaaagagtagaaagagtgatcaaggattttgttttgacatggctggaaaataggccatct
ccttcaaccatctggagattctatcaggagatggctaaagtcataaaggacttccacatg
gtgtctagagagatctgtgatggtgttcttaaaaatgaaatgctgatggaaaagctgaag
aaaggcaagtttgaagtcctggtatcagatccagtattcccttgtggtgatatagtagct
ttaaagctgggaataccattcatctattccttgaggttttctccagcctcaaatgtggaa
aagcactgtgggaaagtaccataccctccttcctatgttcctgctattttatcagaactt
actgaccagatgacatttgcggacagagtaagaaatttcatctcctaccacctacaggac
tacatgtttgaaactctttggaaaccatgggattcctactatagtaaagcattgggaaaa
cccactacgttatgtgagactatgagcaaagctgaaatttggctaattcggacatattgg
gattttgaatttcctcgtccattcttgcctaattttgagtttgttggaggactgcactgc
aaacctgccaaacctttacctaaagaaatggaagaatttgtccagagttctggtgaagat
ggtattgtggtgttttctctggggtcaatggtgaaaaacctcacagaagaaaaggccaat
ctcatcgcctcggccctctctcagattccacagaaggttttgtggagatacaagggaaag
aagccagccatgttaggaccgaatactcagctgtttgattggattccccagaatgacctt
ctcggtcatcccaaaactaaagctttcatcactcatggtggaactaatgggatctatgaa
gctatttatcatgggatccctatggtgggggttcccatgtttgcagatcaacctgacaac
attgctcacatgaaggccaaaggagcagctgtggaggtcaacatgaacacaatgacgagt
gcagacctgctcaatgccttgagaatagtcatcaatgacccttcttataaagagaatgcc
atgaggttatcaagaattcaccatgaccagccagtgaagcccctggaccgagcagtcttc
tggattgagtttgtcatgcgccacaaaggggccaagcaccttcgggttgcagcccacgac
ctgtcctggttccaatatcactctttggatgtgattgggttcctgttgggctgtgtagca
agtgttgtattcttggtcacaaagtgttgtttgttttcctatcaaaaatttattaggaaa
ggaaagaggataaagaaggaatag

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