KEGG   Heterocephalus glaber (naked mole rat): 101717066Help
Entry
101717066         CDS       T02812                                 

Definition
(RefSeq) steroid 21-hydroxylase
  KO
K00513  
steroid 21-monooxygenase [EC:1.14.14.16]
Organism
hgl  Heterocephalus glaber (naked mole rat)
Pathway
Steroid hormone biosynthesis
Metabolic pathways
Aldosterone synthesis and secretion
Module
C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone
Brite
KEGG Orthology (KO) [BR:hgl00001]
 Metabolism
  Lipid metabolism
   00140 Steroid hormone biosynthesis
    101717066
 Organismal Systems
  Endocrine system
   04925 Aldosterone synthesis and secretion
    101717066
Enzymes [BR:hgl01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.16  steroid 21-monooxygenase
     101717066
Cytochrome P450 [BR:hgl00199]
 Cytochrome P450, animal type
  CYP21 family
   101717066
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 
Motif
Other DBs
NCBI-ProteinID: 
NCBI-GeneID: 
Position
Un
AA seq 491 aa AA seqDB search
MLLLLLLVLLLAGTRLLWAQWKLRTLNLPPLAPGFLHLLQPNLPIHLLRLSRKMGPIYRL
HYGLRNVVVLNSKQSIEEAMLRKWVDFAGRPQMQSSKLVCQSYPDLSLGDYSVLWKAHKK
LTRSALLLGARNSMELWVQQLTQEFCQRLRAQAGAPVDIHREFLLLTCGIICGLTFGNKS
DTLVRSICSCVQDLMNAWNHWSIQILDMVPFLRFLPNPGIQRLKQMVEVRDLIVGQQLRQ
HKDSLVAGQWRDLLDYMLQGVEQPGKEQGSEQLQEGHVHMSVVDLFIGGTETTATTLSWA
VAFLLHHPEIQRRLQEELDLELGPDSFTSRLLYKDRKQLPLLNATIAEVLRLRPVVPLAL
PHRTIRPSRIAGYDIPRDTVIIPNIQGANLDETLWERPHEFWPDRFLPLGKSPHELSFGC
GARVCLGESLARLELFVVLTHLLQAFTLLPLEGALPSLQPQPYSGINLLVQPFQVRLQPR
GLGAPCRGQCQ
NT seq 1476 nt NT seq  +upstreamnt  +downstreamnt
atgctcctgctgctcctgctggtgctgctgctggcaggcacccgcctgctgtgggcccag
tggaagctcaggaccctcaacctccctcctctggccccgggcttcctgcacctccttcaa
cccaacctccccatccacctgctcaggctctctcggaaaatggggcccatctaccggctg
cactatgggctgagaaatgtggtggtgctgaactccaagcagtccatagaggaggccatg
ctccggaagtgggtggactttgccggcagaccccagatgcagtcctccaagctggtgtgt
cagagctaccccgacctgtcactgggggactactccgtgctctggaaggcgcacaagaag
ctcacccgctcggccctcctgctgggtgccagaaactccatggagctttgggtgcagcag
ttgacccaggagttctgccagcgcctgagagcccaggctggcgcccccgtggacatccac
agggagttcttgctcctcacctgcggcatcatctgcggcctcacctttggaaacaagagt
gacaccttggtgcggagcatttgcagctgcgtccaggacttgatgaatgcctggaaccac
tggtccatccaaatcctggacatggtccccttcctgaggttcctccccaacccgggcatc
cagaggctgaagcagatggtggaggtcagggacctcatcgtagggcagcagctgaggcag
cacaaggacagcctggtggccgggcagtggagggacctgctggactacatgctccaagga
gtggagcagcccgggaaggagcagggctcggaacagctccaggaaggacacgtgcacatg
tccgtggtggacctcttcatcggcggcaccgagaccacagccaccaccctctcctgggct
gtggccttcctcctgcaccaccctgagattcagcgacgtctccaagaggagctggacctg
gagctgggtcccgactccttcacctcccggctcctgtacaaggaccgcaagcagctgccc
ttgctcaacgccaccatcgctgaggtgctgcgcctgcggcccgtggtgcccttggccctg
ccgcaccgcaccatccgacccagcaggatcgccggctacgacatccccagggacactgtc
atcatccccaacatccaaggtgccaacctggacgagacgctgtgggaacggccccacgag
ttctggcctgaccgcttcctgccgctgggcaagagcccccacgagctgtccttcggctgc
ggggcgcgcgtgtgcctgggtgagtcgctggcccgcctggagctcttcgtggtgctgacg
cacctgctccaggccttcactctgctgccactggagggcgccctgccctctctgcagcct
cagccctacagcggcatcaacctgctggtgcagccttttcaggtgcggctgcagccccgg
ggtctcggggccccgtgccggggccagtgccagtga

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