KEGG   Heterocephalus glaber (naked mole-rat): 101721212
Entry
101721212         CDS       T02812                                 
Symbol
Chek2
Name
(RefSeq) checkpoint kinase 2
  KO
K06641  serine/threonine-protein kinase CHEK2 [EC:2.7.11.1]
Organism
hgl  Heterocephalus glaber (naked mole-rat)
Pathway
hgl04110  Cell cycle
hgl04115  p53 signaling pathway
hgl04218  Cellular senescence
hgl05166  Human T-cell leukemia virus 1 infection
Brite
KEGG Orthology (KO) [BR:hgl00001]
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    101721212 (Chek2)
   04115 p53 signaling pathway
    101721212 (Chek2)
   04218 Cellular senescence
    101721212 (Chek2)
 09160 Human Diseases
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    101721212 (Chek2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hgl01001]
    101721212 (Chek2)
  09182 Protein families: genetic information processing
   03400 DNA repair and recombination proteins [BR:hgl03400]
    101721212 (Chek2)
Enzymes [BR:hgl01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     101721212 (Chek2)
Protein kinases [BR:hgl01001]
 Serine/threonine kinases: CAMK group
  RAD53 family
   101721212 (Chek2)
DNA repair and recombination proteins [BR:hgl03400]
 Eukaryotic type
  Check point factors
   Other check point factors
    101721212 (Chek2)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr FHA Kinase-like Kdo Haspin_kinase RIO1 YrbL-PhoP_reg Pkinase_fungal ABC1 APH
Other DBs
NCBI-GeneID: 101721212
NCBI-ProteinID: XP_012927384
UniProt: A0A0P6J943
Position
Un
AA seq 561 aa
MSRESNAESQQSYSNTSSQAHGSGTSSQTQGGFNQSQGSLSQSPGFASQSHGSLSQSQGT
SSSSAGTVPTSSQSSQSSSGTLSSLETVSTQELCSIPEDQEPEEPVPAPWARLWALQEGF
SNFECVNDNYWFGRDKSCDYCFDEPLLKRTDKYRTYSKKHFRIFREMGPKNSYIAYIEDH
SGNGTFVNTELVGRGKHRPLSNNSEIALSLCRNKVFVFFDLTVDDQSVYPKQLRDEYIIS
KTLGSGACGEVKLAFERKTCKKVAIKIISKRKFAIGSLKELVDSALNVETEIEILKKLNH
PCIIKIKNFFDAEDYYIVLELMEGGELFDRVVGHKHLKEATCKLYFYQMLLAVQYLHENG
IIHRDLKPENVLLSSQEEDCLIKITDFGQSKILGETSLMRTLCGTPTYLAPEVLLSIGTT
GYNRAVDCWSLGVILFICLSGYPPFSEHKTQVSLKDQITSGKYTFIPEVWADVSEKALDL
VKKLLVVDPKARFTTEEALGHPWLQDEDMKRKFQNLLAEENKLLALPQVSPQPSTSRKRP
LKAEAEDTKTTKRPAVCAAVS
NT seq 1686 nt   +upstreamnt  +downstreamnt
atgtctcgagagtcaaatgcagagagtcaacagtcctacagcaacacctcctcacaggcc
catggcagtggtaccagttcacagacccaaggtggcttcaaccagtcacaaggcagtttg
tcccagtcccctgggtttgcttcacagtctcacgggtctttgtcacagtcccaaggcaca
tctagctcctccgctggcacagtgcccacctctagccagtcctctcagtccagctccggg
acgctgagctccttagagaccgtgtccactcaggaactctgttctattcctgaggaccaa
gaacctgaggaacctgttcctgccccttgggctcggctatgggctcttcaggaaggattc
tccaattttgagtgtgttaatgacaactactggtttgggagggataaaagctgtgactat
tgctttgatgaacccctgctaaaaagaacagataaatacaggacatatagcaagaaacac
tttcggattttcagggaaatgggtcctaaaaactcttacatcgcatacatagaagatcac
agtgggaatggaacctttgtaaatacagagcttgtagggagaggaaaacatcgtcctttg
agtaacaattctgaaattgcactttcattatgtagaaataaagtttttgtattttttgat
ctgactgtagatgatcagtcagtttatcccaagcaattaagagatgaatacatcatatca
aaaactcttggaagtggtgcttgtggagaggtaaagctggcttttgagaggaaaacatgt
aagaaagtagccataaagatcatcagcaaaaggaaatttgctattggttctttgaaagag
ttagtagactcagctcttaatgttgaaactgaaatagaaattttgaaaaaactaaaccac
ccttgtatcatcaagattaaaaacttttttgatgcagaagattattacattgttttggaa
ttgatggaagggggagagctgtttgacagggtggtggggcataaacatctgaaagaagct
acctgcaagctctatttttaccagatgcttttggctgtccagtaccttcatgaaaatggg
attatacatcgggatttaaagccagagaatgttctactgtcatctcaggaagaggactgt
cttataaagattactgattttgggcagtccaagattttgggggagacctctctcatgaga
actttatgtggtacccccacttacttggctcctgaggttcttctttctattgggactacg
gggtataaccgagctgtggactgctggagtttaggagttattctttttatctgccttagt
gggtatccacctttctctgagcataagactcaagtctcactgaaggatcagatcaccagt
ggaaagtacaccttcattcctgaagtctgggcagatgtctcagagaaggctctggacctt
gtcaagaagttgttggttgtggatcccaaggcacggtttacaactgaagaagccttaggt
cacccatggcttcaggatgaggacatgaagagaaagtttcagaatctactggctgaggaa
aataagctgttggctctaccccaggtctcaccccagccttccactagtcgaaagcggcct
ctcaaagcagaagctgaggacaccaagaccacaaagcgtccagctgtgtgtgctgctgtg
tcatga

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Ontology (4)   
   KEGG BRITE (4)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (14)   
   KEGG ORTHOLOGY (1)   
   RefGene (10)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (8)   
   UniProt (1)   
   RefSeq(pep) (7)   
DNA sequence (10)   
   RefSeq(nuc) (8)   
   GenBank (1)   
   EMBL (1)   
Protein domain (11)   
   Pfam (11)   
All databases (53)   

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