KEGG   Heterocephalus glaber (naked mole-rat): 101724195
Entry
101724195         CDS       T02812                                 
Symbol
Rock2
Name
(RefSeq) Rho associated coiled-coil containing protein kinase 2
  KO
K17388  Rho-associated protein kinase 2 [EC:2.7.11.1]
Organism
hgl  Heterocephalus glaber (naked mole-rat)
Pathway
hgl04022  cGMP-PKG signaling pathway
hgl04024  cAMP signaling pathway
hgl04062  Chemokine signaling pathway
hgl04071  Sphingolipid signaling pathway
hgl04270  Vascular smooth muscle contraction
hgl04310  Wnt signaling pathway
hgl04360  Axon guidance
hgl04510  Focal adhesion
hgl04520  Adherens junction
hgl04530  Tight junction
hgl04611  Platelet activation
hgl04670  Leukocyte transendothelial migration
hgl04810  Regulation of actin cytoskeleton
hgl04921  Oxytocin signaling pathway
hgl05132  Salmonella infection
hgl05135  Yersinia infection
hgl05163  Human cytomegalovirus infection
hgl05200  Pathways in cancer
hgl05205  Proteoglycans in cancer
hgl05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:hgl00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    101724195 (Rock2)
   04071 Sphingolipid signaling pathway
    101724195 (Rock2)
   04024 cAMP signaling pathway
    101724195 (Rock2)
   04022 cGMP-PKG signaling pathway
    101724195 (Rock2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    101724195 (Rock2)
   04520 Adherens junction
    101724195 (Rock2)
   04530 Tight junction
    101724195 (Rock2)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    101724195 (Rock2)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    101724195 (Rock2)
   04670 Leukocyte transendothelial migration
    101724195 (Rock2)
   04062 Chemokine signaling pathway
    101724195 (Rock2)
  09152 Endocrine system
   04921 Oxytocin signaling pathway
    101724195 (Rock2)
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    101724195 (Rock2)
  09158 Development and regeneration
   04360 Axon guidance
    101724195 (Rock2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    101724195 (Rock2)
   05205 Proteoglycans in cancer
    101724195 (Rock2)
  09172 Infectious disease: viral
   05163 Human cytomegalovirus infection
    101724195 (Rock2)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    101724195 (Rock2)
   05135 Yersinia infection
    101724195 (Rock2)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    101724195 (Rock2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hgl01001]
    101724195 (Rock2)
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:hgl03036]
    101724195 (Rock2)
Enzymes [BR:hgl01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     101724195 (Rock2)
Protein kinases [BR:hgl01001]
 Serine/threonine kinases: AGC group
  DMPK family [OT]
   101724195 (Rock2)
Chromosome and associated proteins [BR:hgl03036]
 Eukaryotic type
  Centrosome formation proteins
   Kinases and associated factors
    101724195 (Rock2)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Rho_Binding PH C1_1 APH Pkinase_C Irp3-like_C
Other DBs
NCBI-GeneID: 101724195
NCBI-ProteinID: XP_004870001
Position
Un
AA seq 1388 aa
MSRAPPPGKMPGDPEEAGPGDGAADRRRKLDALLRDPRSPINVDSLLDGLNSLVLDLDFP
ALRKNKNIDNFLNRYEKVVKKVRGLQMKAEDYDVVKVIGRGAFGEVQLVRHKASQNVYAM
KLLSKFEMIKRSDAAFFWEERDIMAFANSPWVVELFCAFQDDKYLYMVMEYMPGGDLVNL
MSNYDVPEKWAKFYTAEVVLALDVIHSMGLIHRDVKPDNMLLDRHGHLKLADFGTCMKMD
ETGMVHCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLFEMLVGDTPFYADSLV
GTYSKIMDHKNSLSIPEDAEISKHAKNLICAFLTEREVRLGRNGVEEIKQHPFFKNDQWN
WDNIRETAAPVVPELSSDIDSSNFDDIEDDKGDVETFPIPKAFVGNQLPFIGFTYYRDDL
LLSDSPPCRESDSVQSRKNEESQEIQKKLYSLEERFNSELQAKEELEQKCKSINTRLEKT
AKELEEEITLRKNVESALRQLEREKALLQHKNAEYQRKADHEADKKRNLENDVNSLKDQL
EDLKKRNQNSQISTEKVNQLQRQLDETNALLRTESDTAARLRKTQAESSKQIQQLESNNR
DLQDKNCLLETARLKLEKEFINLQSALESERRDWTHRSEIISDLQGRISGLEEDLKNGKI
LLAKVELEKRQLQEKLTDLEKEKSNMEIDMTYQLKVIQQSFEQEEAEHKATKARLADKNK
IYESIEEAKSEAMKEMEKKLLEERTLKQKVENLLLESEKKCSMLDCDLKQSQQKLNELLK
QKDVLNEDVRNLTLKIEQETQKRCLTQNDLKMQTQQVNTLKMSEKQLKQENNHLVEMKLS
LEKQNAELRKERQDADGQMKELQDQLEAEQYFSTLYKTQVRELKEECEEKTKLCKELQQK
KQELQDERDSLAAQLEITLTKADSEQLARSIAEEQYSDLEKEKIMKELEIKEMMARHKQE
LTEKDATIASLEETNRTLTSDVANLANEKEELNNKLKDAQEQLSRLKDEELSATAVKAQF
EKQLLTERTLKTQAVNKLAEIMNRKEPIKRGSDTDVRRKEKENRKLHMELKSEREKLTQQ
MIKYQKELNEMQAQIAEESQIRIELQMTLDSKDSDIEQLRSQLQALHIGLDSSSIGSGPG
DTEAEDGFPESRLEGWLSLPVRNNTKKFGWVKKYVIVSSKKILFYDSEQDKEQSNPYMVL
DIDKLFHVRPVTQTDVYRADAKEIPRIFQILYANEGESKKEQEFPVEPVGEKSNYICHKG
HEFIPTLYHFPTNCEACMKPLWHMFKPPPALECRRCHIKCHKDHLDRKEEIIAPCKVYYD
ISTAKNLLLLANSTEEQQRWVSRLVKKIPKKPPAPDPFARSSPRTSMKIPQNQSVRRPSR
QLAPNKPS
NT seq 4167 nt   +upstreamnt  +downstreamnt
atgagcagggccccgccgcccgggaagatgcctggcgaccccgaggaggccgggcccggg
gacggggccgccgaccgccgcaggaagctggacgcgctgcttcgggacccgcgctcacct
atcaacgtggacagcctgctggatggcttaaattccttggtccttgatttggattttcca
gccttgaggaaaaataagaatatagataatttcttaaatagatatgagaaagttgtgaaa
aaagtccgaggcctgcagatgaaggcggaagactatgatgttgtaaaagtcatcgggaga
ggagctttcggtgaagtgcagttggttcgtcataaggcatcacagaatgtgtatgccatg
aagctgcttagtaagtttgaaatgatcaaaagatcagatgctgcttttttctgggaagaa
agagatattatggcctttgccaatagtccctgggtggttgagctcttctgcgccttccaa
gatgataagtatctatatatggtcatggaatacatgcctggtggggaccttgtaaacctg
atgagtaactacgatgtgcctgagaagtgggccaagttctacactgcagaagtggttctg
gctctggatgtgattcactccatgggtctgatccacagggatgtcaagcctgacaacatg
ctgctggataggcatgggcacctgaagctggcagactttggcacctgtatgaagatggat
gagacaggcatggtgcactgtgacacagcggtcggaaccccagactacatatcaccagag
gttctgaaatcgcaagggggcgacggttattacgggagagagtgtgactggtggtctgtc
ggggttttcctttttgaaatgctagtgggagatactccgttttatgcagattcacttgta
ggaacttacagcaaaattatggatcataaaaattcactatctatccccgaagatgcagaa
atttctaaacatgcaaagaatctcatctgtgccttcttaacagaaagggaggtacgcctt
gggagaaatggggtagaagaaatcaaacagcatcctttctttaagaatgatcaatggaat
tgggataacataagagagacggcagctcctgtagtgcctgagctcagcagtgacatagac
agcagcaacttcgatgatattgaggatgataaaggagatgtcgaaaccttcccaattcct
aaagcttttgtgggaaatcagctgccctttataggatttacctactatagagacgatttg
ttgttaagcgactctccgccttgcagagaaagtgactcagtacaatcaaggaaaaatgaa
gaaagtcaagagattcagaaaaaactgtatagcttagaagaacgctttaacagtgagcta
caagccaaagaggagctcgagcagaagtgcaaatctatcaatactcgcctagagaaaaca
gcaaaggagctagaagaagagattaccttacggaaaaatgtggaatcagcattaagacaa
ttagaaagagaaaaggcgcttcttcagcacaaaaatgcagaatatcaaaggaaagctgat
cacgaagcagacaagaaacgaaatttagaaaatgatgtcaacagcttaaaagatcaactt
gaagatttgaaaaaaagaaaccagaactctcaaatatctaccgagaaagtgaaccagcta
cagagacagctggatgaaacgaatgctttgctgcgaacagaatctgatactgcagcccgg
ttgagaaagacccaggcggaaagttccaaacagattcaacagctggaatccaacaacaga
gatctgcaggataaaaactgcctgctagagactgccaggttaaaactggaaaaggagttt
atcaatcttcagtctgctctggagtcagaaaggagggactggacccacagatcagagatc
atcagtgacttacaaggtagaatatctggcctagaagaagatttaaagaatggcaaaatc
ttactagcaaaagtagaactggagaagagacaactgcaggagaagcttactgatttggaa
aaggaaaagagcaacatggaaatagacatgacataccagctcaaagttatccagcagagc
ttcgagcaggaagaagctgagcacaaggccacgaaagcgcggctcgcagacaaaaataag
atctacgaatccattgaggaagctaaatcggaagccatgaaagaaatggaaaagaagctg
ttggaagaaaggactttaaaacagaaggtagagaacctgctgctggagtcggagaagaag
tgctccatgctggactgcgacctgaagcagtcgcagcagaagctgaacgagctcctcaag
cagaaggacgtgctcaacgaggatgttagaaacttgacgttaaagatagagcaggaaact
cagaagcgctgcctcacacagaatgacctgaagatgcagacacagcaggtgaacacactg
aagatgtcagagaaacagctgaaacaggagaacaaccacctggtggagatgaagctgagc
ttggagaagcagaacgccgagctccgaaaagaacggcaggatgcagatgggcagatgaaa
gagctgcaagatcagcttgaagcagagcagtatttctccaccctctataaaacccaagtt
agggaacttaaagaagaatgcgaagaaaagaccaaactttgtaaagagttacagcagaag
aagcaggagctccaggatgaaagggactccttggccgcccagctggagatcaccttgacc
aaggcggactccgaacagctggctcgctcaattgctgaagaacagtattccgatttggaa
aaggagaagatcatgaaagagctggagatcaaggagatgatggccagacataaacaggag
ctcactgagaaggacgccaccattgcctcgcttgaagaaacaaacaggacactaactagt
gatgttgccaatcttgccaacgagaaagaagaattaaataacaaattgaaagatgctcaa
gagcagctatcaaggctgaaagacgaggagctaagtgccacagctgttaaagcacagttt
gagaaacagctgttgacagagagaacgctcaagactcaggctgtgaataagttggctgag
atcatgaatcgaaaagaacctatcaagcgtggcagtgacacagacgtgcgaaggaaagag
aaggagaatagaaagctgcacatggaactgaagtctgagcgagaaaaattgacccagcag
atgatcaagtaccagaaggaactgaatgaaatgcaggctcaaatagctgaggagagccag
attcgaattgaactgcagatgacactagacagtaaggacagcgacatcgagcagctgcgg
tcgcagctccaggccctgcacattggcctggacagctccagcatcggcagtgggccaggg
gacacggaggcagaggacgggtttccagagtcaagattagaaggatggctttcgttacct
gtgcgaaacaacacgaagaaatttggatgggttaagaagtacgtgattgtgagcagtaag
aagattcttttctatgacagtgaacaagataaagagcagtctaacccttacatggtttta
gatatagacaaattatttcatgtccgaccggttacacagacggatgtctatagagcagat
gctaaagaaattccaaggatattccagatcctgtatgccaatgaaggagagagcaagaag
gaacaggagtttccagtggaaccagtgggagagaaatcgaattacatctgccacaaaggg
catgagttcatccccaccctgtaccacttcccgaccaactgcgaggcctgcatgaagcca
ctgtggcacatgttcaagccccctcccgctctggagtgccgccgctgccacatcaaatgt
cacaaagaccacttggacagaaaggaagagatcatagcgccgtgcaaagtgtattacgac
atatccacggcaaagaatctgctgttactcgccaactccacagaggagcagcagaggtgg
gtgagccgcctggtgaagaagatccctaagaagcccccagcacccgacccctttgcgcgt
tcgtcacccaggacctccatgaagatcccgcagaaccagtcggtccggcggcccagccgg
cagcttgcccccaacaagcccagctaa

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (20)   
   KEGG PATHWAY (20)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (29)   
   KEGG ORTHOLOGY (1)   
   RefGene (25)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (3)   
   RefSeq(pep) (3)   
DNA sequence (3)   
   RefSeq(nuc) (3)   
Protein domain (8)   
   Pfam (8)   
All databases (69)   

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