KEGG T04202: Hhub

Halobacterium hubeiense: Hhub_1488

Entry

Hhub_1488         CDS       T04202

Symbol

topA

Name

(GenBank) DNA topoisomerase 1

K03168

DNA topoisomerase I [EC:5.6.2.1]

Organism

hhb Halobacterium hubeiense

Brite

KEGG Orthology (KO) [BR:hhb00001]
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:hhb03032]
    Hhub_1488 (topA)
   03400 DNA repair and recombination proteins [BR:hhb03400]
    Hhub_1488 (topA)
Enzymes [BR:hhb01000]
5. Isomerases
  5.6  Isomerases altering macromolecular conformation
   5.6.2  Enzymes altering nucleic acid conformation
    5.6.2.1  DNA topoisomerase
     Hhub_1488 (topA)
DNA replication proteins [BR:hhb03032]
Prokaryotic type
  DNA Topoisomerases
   Hhub_1488 (topA)
DNA repair and recombination proteins [BR:hhb03400]
Prokaryotic type
  DSBR (double strand breaks repair)
   NHEJ (non-homologous end-joining)
    SHIIR (short-homology-independent illegitimate recombination)
     Facilitator
      Hhub_1488 (topA)

SSDB

Motif

Pfam:

Topoisom_bac zf-C4_Topoisom Toprim HHH_5 DUF4332 Cdd1 DNA_pol_lambd_f BAF RNA_POL_M_15KD

Other DBs

NCBI-ProteinID:

CQH49104

UniProt:

A0A0U5H3Z6

Position

I:468257..470743

AA seq 828 aa
MELIVTEKNNAARRIADILSEGGATTDTTAGVNVYEWGGRRCIGLSGHVVGMDFPPEYSD
WRDVEPAELVHADVVKEPTQEDIVNALQRLAREADSVVIATDYDREGELIGKEAYELVRD
VNEEAPIQRVRFSSITDNEVKSAFADPDDVDFDLAAAGEARQIIDLVWGAALTRFLSLSA
RQMGEDFISVGRVQSPTLKLIVDKEREIEAFEPDDYWELFADLAKDGTEFEAQYFYEGED
GNEAERVWDEDAAERAFSVLREAGEAVVQSVSRRTRSDDPPAPFNTTQFIRAAGSLGYSA
GRAMSIAEDLYTAGYITYPRTDNTVYPEDLDERELLGEFEQTVFGDDAELLLERDDLSPT
EGDEETTDHPPIHPTPDFPDRNQLSEDEWEVYELVVRRFFATLAEPAVWEHLRVVADADG
ESLKANGKRLLEEGYHAVYPYFNTSENYVPDVDEGDHLDLTDPRMEAKQTQPPRRYGQSR
LIETMEDMGIGTKSTRHNTIEKLYDRGYIEGDPPRPTTLAKAVVEAAEEYADLVVSEQMT
SELEGDMTAIADGEKSLDEVTAESREILDRVFDELTESREEIGDHLRDSLKADKTLGECP
ECGDTLLVRRSRTGSYFVGCDGYPECRFTLPLPSTGEPLVLEETCEEHGLHEVKMLAGRD
TFVHGCPLCAAEEAEESEDRVIGACPECGDEEGGELAIKQLQTGSRLVGCTRYPDCDYSL
PLPRRGDIEVTDTYCDEHDLPELVVHDGDDDEPWELGCPICNYEEYQQRQRKQGVEALDG
IGPATAEKLEDAGIEDVGDLASADADELAESVSGVSAENVREWQAQAD

NT seq 2487 nt +upstreamnt +downstreamnt
gtggaactcatcgtcacagagaagaacaacgccgcgcgacgcatcgccgacatcctctcg
gagggaggggcaaccaccgacacgaccgctggcgtgaacgtctacgagtggggcggccgc
cgctgcatcgggctctccggccacgtcgtcggcatggacttcccgcccgagtacagcgac
tggcgggacgtcgagcccgccgaactcgtgcacgccgacgtcgtcaaggagcccacgcag
gaggacatcgtgaacgcgctccagcggctcgcccgcgaggccgacagcgtcgtcatcgcg
actgactacgaccgcgagggcgaactcatcgggaaggaggcctacgagctcgtgcgcgac
gtcaacgaggaggcgcccatccagcgggtgcgcttctcctcgattacggacaacgaggtg
aagtccgcgttcgcggaccccgacgacgtggacttcgacctcgcggcggcgggcgaagcc
cgccaaatcatcgacctcgtgtggggggccgcgctcactcgattcctctcgctgtccgcc
cggcagatgggcgaggacttcatctccgtaggccgcgtgcagtcgccgacgctgaagctc
atcgtggacaaggagcgcgagatagaggcgttcgagcccgacgactactgggagctgttc
gccgacctcgcgaaagacgggacggagttcgaggcgcagtacttctacgagggtgaggac
ggcaacgaggccgagcgcgtctgggacgaggacgccgccgagcgcgcgttctcggtgctc
cgcgaggccggcgaggcggtcgtgcagtccgtctcccggcgcacccggagcgacgacccg
ccggcgccgttcaacaccacgcagttcatccgcgctgctggctcgctgggctactcggcg
ggccgcgcgatgagcatcgccgaggacctctacacggcgggctacatcacgtacccgcgg
acggacaacaccgtctaccccgaggacttggacgagcgcgaactgctcggggagttcgag
cagaccgtcttcggcgacgacgccgagctgctgctggagcgggacgacctctcgccgacg
gagggcgacgaggagacgaccgaccacccgccgattcacccgaccccggacttccccgac
cggaaccagctctcggaggacgagtgggaggtgtacgagctggtcgtgcggcgcttcttc
gcgacgctcgccgagcccgccgtctgggagcacctgcgtgtcgtcgcggacgccgacggc
gaatccctcaaggcgaacgggaagcgcctgctcgaagaaggctaccacgcggtctacccg
tacttcaacacgagcgagaactacgtgccggacgtcgacgagggcgaccacctcgacctc
accgacccgcggatggaggccaagcagacccagccgccccgccggtacgggcagagccgg
ctcatcgagacgatggaggacatgggcatcgggacgaagtccacgcgccacaacaccatc
gagaagctctacgaccgcggctacatcgagggcgacccgccgcgcccgacgacgctcgcg
aaggcggtcgtggaggccgccgaggagtacgccgacctcgtggtcagcgagcagatgacc
agcgaactggagggcgacatgaccgccatcgcggacggcgagaagtcactcgacgaggtc
accgccgagtcccgcgagattctggaccgcgtcttcgacgagctcaccgagtcccgcgag
gaaatcggcgaccacctccgcgactccctgaaggcggacaagacgctcggggagtgcccc
gagtgcggcgacacgctactcgtgcggcgctcgcggacgggctcgtacttcgtgggctgt
gacggctaccccgagtgtcggttcacgctcccgcttccttcgacgggcgagccgctcgtc
ttggaggagacctgtgaggaacacggactccacgaggtgaagatgctcgcgggccgggac
acgttcgtccacggctgtccgctctgtgcggccgaggaagccgaggagagcgaggaccgc
gtcatcggcgcgtgtcccgagtgcggcgacgaggagggcggcgagctcgctatcaagcag
ctccagaccggcagccggctcgtcggctgcacgcgctacccggactgcgactactcgctg
ccgctcccgcgccgcggcgacatcgaagtcacggacacctactgcgacgaacacgacctc
cccgagctcgtcgtccacgacggcgacgacgacgaaccgtgggagctcggctgccctatc
tgcaactacgaggagtaccagcagcgccagcgcaagcagggcgtggaggcgctggacggc
atcggccccgcgacggcggagaagctcgaagacgcgggcatcgaggacgtcggcgacctc
gcgagcgcggacgccgacgaactcgcggagtcggtgtcgggcgtgagcgcggagaacgtc
cgcgagtggcaggcgcaggcggactag

All links

Ontology (4)   
   KEGG BRITE (4)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (9)   
   Pfam (9)   
All databases (19)   

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