KEGG   Haemophilus influenzae F3047 (nontypeable): HICON_04140
Entry
HICON_04140       CDS       T01400                                 
Name
(GenBank) 2-isopropylmalate synthase
  KO
K01649  2-isopropylmalate synthase [EC:2.3.3.13]
Organism
hil  Haemophilus influenzae F3047 (nontypeable)
Pathway
hil00290  Valine, leucine and isoleucine biosynthesis
hil00620  Pyruvate metabolism
hil01100  Metabolic pathways
hil01110  Biosynthesis of secondary metabolites
hil01210  2-Oxocarboxylic acid metabolism
hil01230  Biosynthesis of amino acids
Module
hil_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:hil00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    HICON_04140
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    HICON_04140
Enzymes [BR:hil01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.3  Acyl groups converted into alkyl groups on transfer
    2.3.3.13  2-isopropylmalate synthase
     HICON_04140
SSDB
Motif
Pfam: HMGL-like LeuA_dimer NAD_binding_10 RdfA
Other DBs
NCBI-ProteinID: CBY85877
Position
complement(159515..161062)
AA seq 515 aa
MTDRVIIFDTTLRDGEQALKASLTVKEKLQIALALERLGVDVMEVGFPVSSQGDFESVQT
IARHIKNARVAALSRAVDKDIDAAYEALKVAEAFRIHTFIASSALHVEAKLKRSFDDVVG
MAVAAVKRARNYTDDVEFSCEDAGRTGIDNICRIVEAAINAGATTVNIPDTVGFCLPNEY
GNIIAQVRNCVPNIDKAVISVHCHNDLGMATANSLTAVQNGARQIECTINGIGERAGNTS
LEEVVMAMKVRQDFMGVDTRINTQEIHRVSQMVSQLCNMPIQPNKAIVGSNAFAHSSGIH
QDGMLKNKNTYEIMSPETIGLKKEKLNLTARSGRAAVKGHMADMGYNEQDYDLDKLYDEF
LKLADKKGQVFDYDLEALAFIDMQQGDEDRLVLDKLSAHSTKEYPATAFVQLKLDGEKLS
TSSIGGNGPVDAVYNAILNLTGLEIKMSHYNLTAKGEGAEALGQVDIVVEHKGRKFHGVG
LATDIVESSALALVHAINAIYRAHKVADIKNHKQH
NT seq 1548 nt   +upstreamnt  +downstreamnt
atgacagatcgcgttattatttttgataccactttgcgtgatggggaacaggcgttaaaa
gcaagtttgacggtaaaagaaaaattacagatcgctttagcacttgaacgcttaggtgtg
gatgtaatggaagtggggtttcctgtttcttctcaaggggattttgaatctgttcaaacc
attgcgcgccatattaaaaacgctcgtgttgccgcgttatctcgagccgtagataaagac
attgatgccgcatacgaagccttaaaagtggcagaagcattccgtattcatacgtttatt
gcaagttccgcattgcacgttgaagcgaaattaaaacgttcttttgatgatgtggtagga
atggcagttgcagcagtgaaacgagcacgtaattatacggatgatgttgagttttcttgc
gaagatgcaggccgtacaggcattgacaatatctgtcgtattgttgaagcggcaattaat
gcgggggcaactacggtaaatattcccgatacagtcggtttttgcttaccaaatgaatac
ggcaatatcattgctcaagtgcgtaattgcgtaccgaatattgataaagcagtgatttcc
gtgcattgccacaatgacttaggtatggcaaccgctaattctttaacggcagtacaaaat
ggtgcgcgccaaattgaatgtaccattaatggaattggcgaacgtgcgggcaatacttcc
cttgaagaagtggttatggcaatgaaagtgcgtcaggattttatgggtgtggatacccgt
attaatacccaagaaattcaccgtgtcagccaaatggtaagccaactttgcaatatgccg
attcagccgaataaagccattgtgggttcaaatgcttttgcccattcttctggtatccat
caagatggtatgttgaaaaacaaaaatacctacgaaattatgtctccggaaaccatcggt
ttgaaaaaagaaaaattgaatttaaccgcacgttctggtcgtgcagctgtgaaaggtcat
atggcagatatgggctataacgaacaagattacgatttggataaattgtatgacgagttc
ttaaaattggcggataaaaaaggtcaagtgtttgattatgatttggaagcattggcgttt
atcgatatgcagcaaggggatgaagatcgtttggtattagataaactttcggcacactcc
accaaagaatatccagcaactgcgtttgttcaattgaagttggatggcgaaaaattaagt
acgtcttcaattggcggtaatggcccagtggatgcggtttataacgccatcttaaattta
acgggtttagaaatcaaaatgtctcactataacttaactgctaaaggcgagggcgcagaa
gcattagggcaagtggatattgtggtagaacacaaagggcgtaaattccacggcgtcggt
ttagcgacagacattgttgaatcttccgcacttgctttagtccacgccatcaatgccatt
tatcgagcgcataaagtggcagatattaagaatcataaacagcattaa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein domain (4)   
   Pfam (4)   
All databases (24)   

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