KEGG   Haemophilus influenzae PittEE (nontypeable): CGSHiEE_06350Help
Entry
CGSHiEE_06350     CDS       T00543                                 

Gene name
ddl
Definition
(GenBank) D-alanine--D-alanine ligase
  KO
K01921  D-alanine-D-alanine ligase [EC:6.3.2.4]
Organism
hip  Haemophilus influenzae PittEE (nontypeable)
Pathway
hip00473  D-Alanine metabolism
hip00550  Peptidoglycan biosynthesis
hip01100  Metabolic pathways
hip01502  Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:hip00001]
 Metabolism
  Metabolism of other amino acids
   00473 D-Alanine metabolism
    CGSHiEE_06350 (ddl)
  Glycan biosynthesis and metabolism
   00550 Peptidoglycan biosynthesis
    CGSHiEE_06350 (ddl)
 Human Diseases
  Drug resistance
   01502 Vancomycin resistance
    CGSHiEE_06350 (ddl)
Enzymes [BR:hip01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.4  D-alanine---D-alanine ligase
     CGSHiEE_06350 (ddl)
Peptidoglycan biosynthesis and degradation proteins [BR:hip01011]
 Precursor biosynthesis
  Amino acid ligase
   CGSHiEE_06350 (ddl)
BRITE hierarchy
SSDB OrthologParalogGene clusterGFIT
Motif
Pfam: Dala_Dala_lig_C Dala_Dala_lig_N ATP-grasp_4 RimK CPSase_L_D2 ATP-grasp_3 ATPgrasp_Ter ATP-grasp ATPgrasp_ST GARS_A TTL
Motif
Other DBs
NCBI-ProteinID: ABQ98617
UniProt: A5UCW6
Position
complement(1256921..1257814)
Genome map
AA seq 297 aa AA seqDB search
MLLGGTSAEREVSFNSGKAVLEALLKQGYNAHPIDPKEYNVANLKKDGFNRAFNILHGRG
GEDGTMQGLLEQIGLPYTGCGVMASALTMDKMRTKMLWKAFGLPVADMKVVTRETFAELD
PQAVVAKLGLPLMVKPSLEGSSVGLTKVKAVEELKSAVEYALKFDNTILIEEWLAGDELT
VSVLDNQVLPAIRIVPEGEFYDYEAKYISDNTQYFCPAGLTPEREQELAILVKRAYDAVG
CRGWSRIDVMCDAKGNFRLVEVNTNPGMTSHSLFPKSAATVGISFEQLVVKILELSL
NT seq 894 nt NT seq  +upstreamnt  +downstreamnt
gtgttattaggcggcacatctgctgaacgtgaagtttctttcaattcaggcaaagcggta
ttagaagcattattaaagcaaggttataatgcacatcctattgatcctaaagaatataat
gttgcaaatcttaaaaaggatggctttaatcgagcatttaatattttgcacggtcgtggt
ggagaagatggcacaatgcaaggtttattagagcaaattggtttgccttatacggggtgt
ggcgtgatggcttctgcattaacgatggacaaaatgcgtacaaaaatgttgtggaaagct
tttggtttacctgttgcagatatgaaagtggttacccgagaaacttttgctgaattagat
cctcaggctgttgtggcaaaattaggcttaccattaatggttaaaccctctttagaaggc
tctagcgttggcttaacgaaagtaaaagcggtagaagagttaaaaagtgcggtggaatat
gcgcttaaatttgataataccattctaattgaagagtggttagctggcgatgaattaact
gtgtctgtgcttgacaatcaagtattacccgcaattcgtattgttcctgagggcgaattt
tatgattatgaagcgaagtatatttctgataatacgcaatatttctgcccagcaggttta
acgcctgaacgcgagcaagagttagcaatattagtaaaacgtgcttatgatgcagtggga
tgtcgtggttggagtcgtattgatgtaatgtgtgatgcaaaaggtaatttccgtttggtt
gaggttaatactaatcctggaatgacgagccatagtttattcccaaaatctgcagcgaca
gtaggtatttcttttgagcaactcgtcgtgaaaattttggagttgagcctgtaa

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