KEGG   Helicobacter pylori SJM180: HPSJM_00305
Entry
HPSJM_00305       CDS       T01323                                 
Name
(GenBank) Proline/pyrroline-5-carboxylate dehydrogenase
  KO
K13821  RHH-type transcriptional regulator, proline utilization regulon repressor / proline dehydrogenase / delta 1-pyrroline-5-carboxylate dehydrogenase [EC:1.5.5.2 1.2.1.88]
Organism
hpm  Helicobacter pylori SJM180
Pathway
hpm00250  Alanine, aspartate and glutamate metabolism
hpm00330  Arginine and proline metabolism
hpm01100  Metabolic pathways
hpm01110  Biosynthesis of secondary metabolites
Module
hpm_M00970  Proline degradation, proline => glutamate
Brite
KEGG Orthology (KO) [BR:hpm00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00250 Alanine, aspartate and glutamate metabolism
    HPSJM_00305
   00330 Arginine and proline metabolism
    HPSJM_00305
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:hpm03000]
    HPSJM_00305
Enzymes [BR:hpm01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.1  With NAD+ or NADP+ as acceptor
    1.2.1.88  L-glutamate gamma-semialdehyde dehydrogenase
     HPSJM_00305
  1.5  Acting on the CH-NH group of donors
   1.5.5  With a quinone or similar compound as acceptor
    1.5.5.2  proline dehydrogenase
     HPSJM_00305
Transcription factors [BR:hpm03000]
 Prokaryotic type
  Ribbon-helix-helix
   Other families
    HPSJM_00305
SSDB
Motif
Pfam: Aldedh Pro_dh
Other DBs
NCBI-ProteinID: ADO01671
UniProt: E1Q172
Position
complement(57777..61334)
AA seq 1185 aa
MQKIIDDSLELAKKLQDSISNHLSEQEKAFHSKMQKLLNNPENKVMLIELMDRSFRCLDN
KARFEMIEHVLDKYKSREIFSSFEKLLLMGFLSFGKMLPDMSVPFFVNKIRSDTKAMVLD
QEESQLKERILKRKNEKIILNVNFIGEEVLGEEEANARFEKYSQALKSNYIQYISIKITT
IFSQINILDFEYSKKEIVKRLDALYALALEEEKKQGMPKFINLDMEEFRDLELTVESFME
SIAKFDLNAGIVLQAYIPDSYEYLKKLHAFSKERVLKGLKPIKIRFVKGANMESEETIAS
VKDWALPTFSNKQDTDSNYNKMLDFVLEGDNYKYIHIGAASHNIFEIAYVYTRIHALNDP
VVLEHFSFEMLEGMSLQASQELKEMHKLILYAPVCDEAHFNNAIAYLVRRLDENTSSDNF
MKAFFNLKVGTSEWKDQEQRFLNSLKGIATLDNATHRTQDRNAKQSGHTTYPNHSFKNES
DTDFILKANREWAKKVREKMHNAPILELYPEMDGRFEDPNLTPLEVFDKIHHKKIASVHL
ADREAILKALEVAKSDKSHFSQKSFTEIHALMSQTAQLFRERRGDLIGISALEVGKTFAE
TDAEVSEAIDFLEFYPYSLRVLQGQNKKTKFTPKGVGVVIAPWNFPVGISVGTIAAPLAA
GNRVIYKPSSLSSVTGYKLCECFWDAGVPRDALIYLPSKGSDISEHLLKDESIQFAILTG
GEDTAYKMLKANPTLALSAETGGKNATIVSKMADRDQAIKNVIHSAFSNSGQKCSATSLL
VLEKEVYEDENFKKTLIDATLSLSVGDPFDFKNKIGTLADKPNEKVIKAIDELRSYENYE
IPVSFVNDNPYLMKPSIKYGTKKGDFTHQTELFTPILSVMKAQDLDEAIEIVNSTGYGLT
SALESLDEREWEYYLERIEAGNIYINKPTTGAIVLRQPFGGVKKSAVGFGRKVGIFNYIT
QFVNIHQEEEDENTLKNPLSEALEGLTQKGYDEHTHELKRAIFMAKSYAYHYKHEFSQAK
DYVKIRGEDNLFSYTKVKSVGYRITEKDTLSDMLGVVLACLVSQIPLTLSIENERANKDL
SFFLECLKALQANAPIVYESLQKFSEKLNAFNRVRYLKSDLDLLHKQASALGMVLATAKP
CLNGRFELLYYHLERSVSISYHRYGNLGSRVLRQPTCHKSCCAEK
NT seq 3558 nt   +upstreamnt  +downstreamnt
atgcaaaaaatcattgacgattcattagaattagctaaaaaactgcaagatagtatcagt
aaccatttgagcgagcaagaaaaagcgttccactctaaaatgcaaaagcttttaaataac
cctgaaaacaaagtcatgctcatagagcttatggatcggagttttagatgcctagacaat
aaagcccgctttgaaatgattgagcatgttttagacaaatacaaaagccgtgagattttt
tcttcatttgaaaaattgcttttaatgggctttttaagctttgggaaaatgctccctgat
atgagcgtgcctttctttgtcaataaaatcagaagcgacacgaaagcgatggtcttggat
caagaagagagccaattaaaagagcggattttaaaaagaaaaaatgaaaaaatcattttg
aatgtgaattttattggcgaagaggttttaggcgaagaagaagctaatgcgcgttttgaa
aaatactctcaagccctaaaatccaactacattcaatacatttccattaaaatcacaacg
attttttctcaaatcaatatccttgattttgaatactctaaaaaagagattgtcaaacgc
ctagacgctctttatgccctggctttagaagaagaaaaaaagcaaggcatgcctaaattt
atcaatttggatatggaggaatttagggatttagagctcacggtggagtcttttatggaa
tccatcgctaaatttgatttgaacgctggtattgtgttgcaagcctatatcccggattct
tatgaatatttgaaaaaactgcacgctttttctaaagaaagggttttaaaagggttaaag
cccattaaaatccgctttgttaagggagcgaatatggagagcgaagagactatcgcttcc
gtgaaagactgggcgttacccacattttccaataagcaagacaccgattctaattacaat
aaaatgctggattttgttttagagggcgataattataaatacattcatattggtgcagca
agccataatatttttgaaatcgcttatgtttatacgcgcatccatgcccttaatgaccct
gttgtgttagagcattttagctttgaaatgctagagggcatgagcttgcaagcgagccag
gaactaaaagagatgcacaaactcattctttatgcaccggtgtgcgatgaagcgcatttt
aacaatgcgatcgcttacttggtgaggaggctagatgaaaacacctcaagcgataatttc
atgaaagctttctttaacctcaaagtaggcacgagcgaatggaaagaccaagagcaacgc
tttttaaacagccttaaaggaatcgctactttagacaatgccacccacaggactcaagat
agaaacgccaaacaaagcgggcataccacttacccaaaccactcctttaaaaacgaaagc
gataccgattttattttaaaagccaaccgagaatgggctaaaaaagtgcgcgaaaaaatg
cataacgcccctattttagaactttacccagaaatggatgggaggtttgaagatcctaat
ttaacccctttagaagtctttgataaaatccatcataaaaaaatcgctagcgtgcattta
gcggatagggaagcgattttaaaagccctagaagtggctaaaagcgataagagccatttc
agtcaaaaaagctttacagaaatccatgccttaatgagtcaaaccgcccagctttttaga
gaaaggcgaggcgatttgatagggatttcggctttagaagtgggtaagactttcgctgaa
acagacgctgaagtgagcgaagccattgactttttagagttttacccttacagcttaagg
gtgttacaagggcaaaataaaaagacgaaattcacccccaaaggcgtgggtgtggtcatt
gccccatggaatttccctgtgggcatttctgtaggcactatcgctgcccccctagccgct
ggcaatcgggtgatttacaagccctcaagtttgtctagcgtaacgggttataagctttgt
gagtgcttttgggatgcgggcgtgccaagagatgcgctcatttacttgccctccaaaggg
agcgatattagcgaacaccttttaaaagatgaaagcatccagtttgctattttaaccggg
ggcgaagacaccgcttataaaatgctaaaagctaatcccactttagccttgagcgctgaa
acgggcggtaaaaacgccaccattgtgagcaaaatggcagacagggatcaagcgattaag
aacgttatccattcagcttttagcaattcggggcaaaaatgctccgccacttcgctttta
gtgttggaaaaagaagtttatgaagatgagaatttcaaaaagactttgatagacgcgact
ctaagccttagcgttggcgatccttttgatttcaaaaacaaaattggcactctagcggac
aagcctaatgaaaaggtcatcaaagccatagacgaattgagaagctatgaaaattacgaa
atcccggtaagctttgtcaatgataacccctatttgatgaagccaagcatcaaatacggc
actaaaaaaggcgatttcacgcaccaaactgagctttttacacccattttatccgtgatg
aaagcgcaagatttagacgaagcgatagagatagtcaattctaccggttacgggctgacg
agcgcgttagagtctttggacgaaagggagtgggaatattatttagaacgcattgaagcc
ggtaatatctatatcaacaaacccaccacaggagcgattgtcttacgccagccttttggg
ggggttaaaaaatcggctgtggggtttgggagaaaggtgggcatttttaactatatcacg
caatttgtgaatattcaccaagaagaagaagatgaaaacaccctaaaaaaccccttaagc
gaagctttagagggcttgactcaaaaaggctatgatgaacacacgcatgagttgaagcgc
gcgatttttatggcaaagagttacgcttatcattacaagcatgaattcagccaagctaaa
gactatgtcaaaatcagaggcgaagacaaccttttttcctacactaaagttaaaagcgtg
ggctatcgcatcaccgaaaaagacactttaagcgatatgttaggcgttgttttagcatgt
ttagtttctcaaatccctttaacgctcagcatagaaaacgaacgagcgaacaaagattta
tcatttttcttagaatgcttaaaagcgctccaagcaaacgcccctattgtttatgaaagc
ttgcaaaaatttagcgaaaaattgaacgctttcaatcgtgtccgttatttaaaaagcgat
ttggatttattgcacaagcaagcgagcgctttagggatggttttagccacggctaaaccc
tgcttgaacgggcgttttgaattgctgtattaccacttagagcgatcggttagcatctct
tatcatcgttacgggaatttaggctcaagggttttaaggcaaccaacttgccacaaatca
tgctgtgctgaaaaataa

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (5)   
   KEGG PATHWAY (4)   
   KEGG MODULE (1)   
Chemical substance (15)   
   KEGG COMPOUND (15)   
Chemical reaction (10)   
   KEGG ENZYME (2)   
   KEGG REACTION (8)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (2)   
   Pfam (2)   
All databases (40)   

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