KEGG H.sapiens: 10327

Homo sapiens (human): 10327

Entry

10327 CDS H.sapiens

Gene name AKR1A1

Definition aldo-keto reductase family 1, member A1 (aldehyde reductase)
(EC:1.1.1.2)

Orthology K00002 alcohol dehydrogenase (NADP+) [EC:1.1.1.2]

Pathway hsa00010 Glycolysis / Gluconeogenesis
hsa00561 Glycerolipid metabolism
hsa01100 Metabolic pathways

Class Metabolism; Carbohydrate Metabolism; Glycolysis / Gluconeogenesis
[PATH:hsa00010]
Metabolism; Lipid Metabolism; Glycerolipid metabolism
[PATH:hsa00561]

SSDB

Motif Pfam: Aldo_ket_red
PROSITE: ALDOKETO_REDUCTASE_2 ALDOKETO_REDUCTASE_1
ALDOKETO_REDUCTASE_3

Other DBs NCBI-GI: 5174391
NCBI-GeneID: 10327
OMIM: 103830
HGNC: 380
HPRD: 00069
Ensembl: ENSG00000117448
UniProt: P14550

Structure

PDB: 2ALR

Position 1p33-p32

AA seq 325 aa
MAASCVLLHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEAL
KEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFER
GDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRP
AVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEPVLLEEPVVLALAEK
YGRSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQLNALNKNWRYIV
PMLTVDGKRVPRDAGHPLYPFNDPY

NT seq 978 nt +upstreamnt +downstreamnt
atggcggcttcctgtgttctactgcacactgggcagaagatgcctctgattggtctgggt
acctggaagagtgagcctggtcaggtaaaagcagctgttaagtatgcccttagcgtaggc
taccgccacattgattgtgctgctatctacggcaatgagcctgagattggggaggccctg
aaggaggacgtgggaccaggcaaggcggtgcctcgggaggagctgtttgtgacatccaag
ctgtggaacaccaagcaccaccccgaggatgtggagcctgccctccggaagactctggct
gacctccagctggagtatctggacctgtacctgatgcactggccttatgcctttgagcgg
ggagacaaccccttccccaagaatgctgatgggactatatgctacgactccacccactac
aaggagacttggaaggctctggaggcactggtggctaaggggctggtgcaggcgctgggc
ctgtccaacttcaacagtcggcagattgatgacatactcagtgtggcctccgtgcgtcca
gctgtcttgcaggtggaatgccacccatacttggctcaaaatgagctaattgcccactgc
caagcacgtggcctggaggtaactgcttatagccctttgggctcctctgatcgtgcatgg
cgtgatcctgatgagcctgtcctgctggaggaaccagtagtcctggcattggctgaaaag
tatggccgatctccagctcagatcttgctcaggtggcaggtccagcggaaagtgatctgc
atccccaaaagtatcactccttctcgaatccttcagaacatcaaggtgtttgacttcacc
tttagcccagaagagatgaagcagctaaatgccctgaacaaaaattggagatatattgtg
cctatgcttacggtggatgggaagagagtcccaagggatgcagggcatcctctgtacccc
tttaatgacccgtactga

All links

Pathway (3)   
   KEGG PATHWAY (3)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (16)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (10)   
   UNIGENE (1)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
Protein sequence (5)   
   UniProt (1)   
   RefSeq(pep) (2)   
   IPI (2)   
DNA sequence (12)   
   RefSeq(nuc) (2)   
   GenBank (5)   
   EMBL (5)   
3D Structure (1)   
   PDB (1)   
Protein domain (4)   
   Pfam (1)   
   PROSITE (3)   
All databases (44)

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