KEGG H.sapiens: 11112

Homo sapiens (human): 11112

Entry

11112 CDS H.sapiens

Gene name HIBADH

Definition 3-hydroxyisobutyrate dehydrogenase (EC:1.1.1.31)

Orthology K00020 3-hydroxyisobutyrate dehydrogenase [EC:1.1.1.31]

Pathway hsa00280 Valine, leucine and isoleucine degradation
hsa01100 Metabolic pathways

Class Metabolism; Amino Acid Metabolism; Valine, leucine and isoleucine
degradation [PATH:hsa00280]

SSDB

Motif Pfam: NAD_binding_2 2-Hacid_dh_C F420_oxidored 3HCDH_N IlvN TrkA_N
UDPG_MGDP_dh_N NAD_Gly3P_dh_N DUF970
PROSITE: 3_HYDROXYISOBUT_DH

Other DBs NCBI-GI: 23308751
NCBI-GeneID: 11112
OMIM: 608475
HGNC: 4907
HPRD: 12238
Ensembl: ENSG00000106049
UniProt: P31937 Q546Z2

Structure

PDB: 2GF2 2I9P

Position 7p15.2

AA seq 336 aa
MAASLRLLGAASGLRYWSRRLRPAAGSFAAVCSRSVASKTPVGFIGLGNMGNPMAKNLMK
HGYPLIIYDVFPDACKEFQDAGEQVVSSPADVAEKADRIITMLPTSINAIEAYSGANGIL
KKVKKGSLLIDSSTIDPAVSKELAKEVEKMGAVFMDAPVSGGVGAARSGNLTFMVGGVED
EFAAAQELLGCMGSNVVYCGAVGTGQAAKICNNMLLAISMIGTAEAMNLGIRLGLDPKLL
AKILNMSSGRCWSSDTYNPVPGVMDGVPSANNYQGGFGTTLMAKDLGLAQDSATSTKSPI
LLGSLAHQIYRMMCAKGYSKKDFSSVFQFLREEETF

NT seq 1011 nt +upstreamnt +downstreamnt
atggcagcctccttacggctcctcggagctgcctccggtctccggtactggagccggcgg
ctgcggccggcagccggcagctttgcagcggtgtgttctaggtcagtggcttcaaagact
ccagttggattcattggactgggcaacatggggaatccaatggcaaaaaatctcatgaaa
catggctatccacttattatttatgatgtgttccctgatgcctgcaaagagtttcaagat
gcaggtgaacaggtagtatcttccccagcagatgttgctgaaaaagctgacagaattatt
acaatgctgcccaccagtatcaatgcaatagaagcttattccggagcaaatgggattcta
aaaaaagtgaagaagggctcattattaatagattccagcactattgatcctgcagtttca
aaagaattggccaaagaagttgagaaaatgggagcagttttcatggatgcccctgtttct
ggtggtgtaggagctgcacgatctgggaacctcacgtttatggtgggaggagttgaagat
gaatttgctgctgcccaagagttgctggggtgcatgggctccaacgtggtgtactgtgga
gctgttgggactgggcaggcggcaaagatctgcaacaacatgctgttagctattagtatg
attggaactgctgaagctatgaatcttggaatcaggttagggcttgacccaaaactactg
gctaaaatcctaaatatgagctcaggacggtgttggtcaagtgacacttataatcctgta
cctggagtgatggatggcgttccctcggctaataactatcagggtggatttggaacaaca
ctcatggctaaggatctgggattggcacaagactctgctaccagcacaaagagcccaatc
cttcttggcagtctggcccatcagatctacaggatgatgtgtgcaaagggctactcaaag
aaagacttctcatccgtgttccagttcctacgagaggaggagaccttctga

All links

Pathway (2)   
   KEGG PATHWAY (2)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (13)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (7)   
   UNIGENE (1)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
Protein sequence (6)   
   UniProt (2)   
   RefSeq(pep) (1)   
   IPI (3)   
DNA sequence (11)   
   RefSeq(nuc) (1)   
   GenBank (5)   
   EMBL (5)   
3D Structure (2)   
   PDB (2)   
Protein domain (10)   
   Pfam (9)   
   PROSITE (1)   
All databases (47)

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