| Entry |
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| Gene name |
CSF2RA, CD116, CDw116, CSF2R, CSF2RAX, CSF2RAY, CSF2RX, CSF2RY, GM-CSF-R-alpha, GMCSFR, GMR, SMDP4
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| Definition |
colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
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| Orthology |
| granulocyte-macrophage colony-stimulating factor receptor alpha |
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| Organism |
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| Pathway |
| Cytokine-cytokine receptor interaction | | Jak-STAT signaling pathway | | Hematopoietic cell lineage | | Pathways in cancer |
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| Disease |
| Pulmonary alveolar proteinosis (PAP) |
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| Drug target |
Molgramostim: Sargramostim: Other: |
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| Class |
Environmental Information Processing; Signal transduction; Jak-STAT signaling pathway [PATH: hsa04630]
Environmental Information Processing; Signaling molecules and interaction; Cytokine-cytokine receptor interaction [PATH: hsa04060]
Organismal Systems; Immune system; Hematopoietic cell lineage [PATH: hsa04640]
Human Diseases; Cancers; Pathways in cancer [PATH: hsa05200]
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| SSDB |
   |
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| Motif |
 |
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| Other DBs |
NCBI-GI: NCBI-GeneID: OMIM: HGNC: HPRD: Ensembl: Vega: UniProt: |
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| Structure |
PDB: |
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| Position |
Xp22.32 and Yp11.3
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| AA seq |
400 aa  
MLLLVTSLLLCELPHPAFLLIPEKSDLRTVAPASSLNVRFDSRTMNLSWDCQENTTFSKC
FLTDKKNRVVEPRLSNNECSCTFREICLHEGVTFEVHVNTSQRGFQQKLLYPNSGREGTA
AQNFSCFIYNADLMNCTWARGPTAPRDVQYFLYIRNSKRRREIRCPYYIQDSGTHVGCHL
DNLSGLTSRNYFLVNGTSREIGIQFFDSLLDTKKIERFNPPSNVTVRCNTTHCLVRWKQP
RTYQKLSYLDFQYQLDVHRKNTQPGTENLLINVSGDLENRYNFPSSEPRAKHSVKIRAAD
VRILNWSSWSEAIEFGSDDGNLGSVYIYVLLIVGTLVCGIVLGFLFKRFLRIQRLFPPVP
QIKDKLNDNHEVEDEIIWEEFTPEEGKGYREEVLTVKEIT |
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| NT seq |
1203 nt  +upstreamnt +downstreamnt
atgcttctcctggtgacaagccttctgctctgtgagttaccacacccagcattcctcctg
atcccagagaaatcggatctgcgaacagtggcaccagcctctagtctcaatgtgaggttt
gactccaggacgatgaatttaagctgggactgccaagaaaacacaaccttcagcaagtgt
ttcttaactgacaagaagaacagagtcgtggaacccaggctcagtaacaacgaatgttcg
tgcacatttcgtgaaatttgtctgcatgaaggagtcacatttgaggttcacgtgaatact
agtcaaagaggatttcaacagaaactgctttatccaaattcaggaagggagggtaccgct
gctcagaatttctcctgtttcatctacaatgcggatttaatgaactgtacctgggcgagg
ggtccgacggccccccgtgacgtccagtattttttgtacatacgaaactcaaagagaagg
agggagatccggtgtccttattacatacaagactcaggaacccatgtgggatgtcacctg
gataacctgtcaggattaacgtctcgcaattactttctggttaacggaaccagccgagaa
attggcatccaattctttgattcacttttggacacaaagaaaatagaacgattcaaccct
cccagcaatgtcaccgtacgttgcaacacgacgcactgcctcgtacggtggaaacagccc
aggacctatcagaagctgtcgtacctggactttcagtaccagctggacgtccacagaaag
aatacccagcctggcacggaaaacctactgattaatgtttctggtgatttggaaaataga
tacaactttccaagctctgagcccagagcaaaacacagtgtgaagatcagagctgcagac
gtccgcatcttgaattggagctcctggagtgaagccattgaatttggttctgacgacggg
aacctcggctctgtgtacatttatgtgctcctaatcgtgggaacccttgtctgtggcatc
gtcctcggcttcctctttaaaaggttccttaggatacagcggctgttcccgccagttcca
cagatcaaagacaaactgaatgataaccatgaggtggaagacgagatcatctgggaggaa
ttcaccccagaggaagggaaaggctaccgcgaagaggtcttgaccgtgaaggaaattacc
tga |
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