KEGG H.sapiens: 1553

Homo sapiens (human): 1553

Entry

1553 CDS H.sapiens

Gene name CYP2A13

Definition cytochrome P450, family 2, subfamily A, polypeptide 13
(EC:1.14.14.1)

Orthology K07411 cytochrome P450, family 2, subfamily A [EC:1.14.14.1]

Pathway hsa00232 Caffeine metabolism
hsa00830 Retinol metabolism
hsa00982 Drug metabolism - cytochrome P450
hsa00983 Drug metabolism - other enzymes
hsa01100 Metabolic pathways

Class Metabolism; Metabolism of Cofactors and Vitamins; Retinol metabolism
[PATH:hsa00830]
Metabolism; Biosynthesis of Secondary Metabolites; Caffeine
metabolism [PATH:hsa00232]
Metabolism; Xenobiotics Biodegradation and Metabolism; Drug
metabolism - cytochrome P450 [PATH:hsa00982]
Metabolism; Xenobiotics Biodegradation and Metabolism; Drug
metabolism - other enzymes [PATH:hsa00983]

SSDB

Motif Pfam: p450
PROSITE: CYTOCHROME_P450

Other DBs NCBI-GI: 13699809
NCBI-GeneID: 1553
OMIM: 608055
HGNC: 2608
HPRD: 07454
Ensembl: ENSG00000197838
UniProt: Q16696

Structure

PDB: 2P85

Position 19q13.2

AA seq 494 aa
MLASGLLLVTLLACLTVMVLMSVWRQRKSRGKLPPGPTPLPFIGNYLQLNTEQMYNSLMK
ISERYGPVFTIHLGPRRVVVLCGHDAVKEALVDQAEEFSGRGEQATFDWLFKGYGVAFSN
GERAKQLRRFSIATLRGFGVGKRGIEERIQEEAGFLIDALRGTHGANIDPTFFLSRTVSN
VISSIVFGDRFDYEDKEFLSLLRMMLGSFQFTATSTGQLYEMFSSVMKHLPGPQQQAFKE
LQGLEDFIAKKVEHNQRTLDPNSPRDFIDSFLIRMQEEEKNPNTEFYLKNLVMTTLNLFF
AGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQPKFEDRAKMPYTEAVIHEIQ
RFGDMLPMGLAHRVNKDTKFRDFFLPKGTEVFPMLGSVLRDPRFFSNPRDFNPQHFLDKK
GQFKKSDAFVPFSIGKRYCFGEGLARMELFLFFTTIMQNFRFKSPQSPKDIDVSPKHVGF
ATIPRNYTMSFLPR

NT seq 1485 nt +upstreamnt +downstreamnt
atgctggcctcagggctgcttctggtgaccttgctggcctgcctgactgtgatggtcttg
atgtcagtctggcggcagaggaagagcagggggaagctgcctccgggacccaccccattg
cccttcattggaaactacctgcagctgaacacagagcagatgtacaactccctcatgaag
atcagtgagcgctatggccctgtgttcaccattcacttggggccccggcgggtcgtggtg
ctgtgcggacatgatgccgtcaaggaggctctggtggaccaggctgaggagttcagcggg
cgaggcgagcaggccaccttcgactggctcttcaaaggctatggcgtggcgttcagcaac
ggggagcgcgccaagcagctccggcgcttctccatcgccaccctaaggggttttggcgtg
ggcaagcgcggcatcgaggaacgcatccaggaggaggcgggcttcctcatcgacgccctc
cggggcacgcacggcgccaatatcgatcccaccttcttcctgagccgcacagtctccaat
gtcatcagctccattgtctttggggaccgctttgactatgaggacaaagagttcctgtca
ctgttgcgcatgatgctgggaagcttccagttcacggcaacctccacggggcagctctat
gagatgttctcttcggtgatgaaacacctgccaggaccacagcaacaggcctttaaggag
ctgcaagggctggaggacttcatcgccaagaaggtggagcacaaccagcgcacgctggat
cccaattccccacgggacttcatcgactcctttctcatccgcatgcaggaggaggagaag
aaccccaacacagagttctacttgaagaacctggtgatgaccaccctgaacctcttcttt
gcgggcactgagaccgtgagcaccaccctgcgctacggtttcctgctgctcatgaagcac
ccagaggtggaggccaaggtccatgaggagattgacagagtgatcggcaagaaccggcag
cccaagtttgaggaccgggccaagatgccctacacagaggcagtgatccacgagatccaa
agatttggagacatgctccccatgggtttggcccacagggtcaacaaggacaccaagttt
cgggatttcttcctccctaagggcactgaagtgttccctatgctgggctccgtgctgaga
gaccccaggttcttctccaacccccgggacttcaatccccagcacttcctggataagaag
gggcagtttaagaagagtgatgcttttgtgcccttttccatcggaaagcggtactgtttt
ggagaaggcctggccagaatggagctctttctcttcttcaccaccatcatgcagaacttt
cgcttcaagtcccctcagtcgcctaaggatatcgacgtgtcccccaaacacgtgggcttt
gccacgatcccacgaaactacaccatgagcttcctgccccgctga

All links

Pathway (5)   
   KEGG PATHWAY (5)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (9)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (3)   
   UNIGENE (1)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
Protein sequence (4)   
   UniProt (1)   
   RefSeq(pep) (1)   
   IPI (2)   
DNA sequence (7)   
   RefSeq(nuc) (1)   
   GenBank (3)   
   EMBL (3)   
3D Structure (1)   
   PDB (1)   
Protein domain (2)   
   Pfam (1)   
   PROSITE (1)   
All databases (31)

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