KEGG H.sapiens: 1562

Homo sapiens (human): 1562

Entry

1562 CDS H.sapiens

Gene name CYP2C18

Definition cytochrome P450, family 2, subfamily C, polypeptide 18
(EC:1.14.14.1)

Orthology K07413 cytochrome P450, family 2, subfamily C [EC:1.14.14.1]

Pathway hsa00590 Arachidonic acid metabolism
hsa00591 Linoleic acid metabolism
hsa00830 Retinol metabolism
hsa00980 Metabolism of xenobiotics by cytochrome P450
hsa00982 Drug metabolism - cytochrome P450
hsa01100 Metabolic pathways

Class Metabolism; Lipid Metabolism; Arachidonic acid metabolism
[PATH:hsa00590]
Metabolism; Lipid Metabolism; Linoleic acid metabolism
[PATH:hsa00591]
Metabolism; Metabolism of Cofactors and Vitamins; Retinol metabolism
[PATH:hsa00830]
Metabolism; Xenobiotics Biodegradation and Metabolism; Metabolism of
xenobiotics by cytochrome P450 [PATH:hsa00980]
Metabolism; Xenobiotics Biodegradation and Metabolism; Drug
metabolism - cytochrome P450 [PATH:hsa00982]
Metabolism; Enzyme Families; Cytochrome P450

SSDB

Motif Pfam: p450
PROSITE: CYTOCHROME_P450

Other DBs NCBI-GI: 13699816
NCBI-GeneID: 1562
OMIM: 601131
HGNC: 2620
HPRD: 03085
Ensembl: ENSG00000108242
UniProt: P33260 Q7Z348

Position 10q24

AA seq 490 aa
MDPAVALVLCLSCLFLLSLWRQSSGRGRLPSGPTPLPIIGNILQLDVKDMSKSLTNFSKV
YGPVFTVYFGLKPIVVLHGYEAVKEALIDHGEEFSGRGSFPVAEKVNKGLGILFSNGKRW
KEIRRFCLMTLRNFGMGKRSIEDRVQEEARCLVEELRKTNASPCDPTFILGCAPCNVICS
VIFHDRFDYKDQRFLNLMEKFNENLRILSSPWIQVCNNFPALIDYLPGSHNKIAENFAYI
KSYVLERIKEHQESLDMNSARDFIDCFLIKMEQEKHNQQSEFTVESLIATVTDMFGAGTE
TTSTTLRYGLLLLLKYPEVTAKVQEEIECVVGRNRSPCMQDRSHMPYTDAVVHEIQRYID
LLPTNLPHAVTCDVKFKNYLIPKGTTIITSLTSVLHNDKEFPNPEMFDPGHFLDKSGNFK
KSDYFMPFSAGKRMCMGEGLARMELFLFLTTILQNFNLKSQVDPKDIDITPIANAFGRVP
PLYQLCFIPV

NT seq 1473 nt +upstreamnt +downstreamnt
atggatccagctgtggctctggtgctctgtctctcctgtttgtttctcctttcactctgg
aggcagagctctggaagagggaggctcccgtctggccccactcctctcccgattattgga
aatatcctgcagttagatgttaaggacatgagcaaatccttaaccaatttctcaaaagtc
tatggccctgtgttcactgtgtattttggcctgaagcccattgtggtgttgcatggatat
gaagcagtgaaggaggccctgattgatcatggagaggagttttctggaagaggaagtttt
ccagtggctgaaaaagttaacaaaggacttggaatccttttcagcaatggaaagagatgg
aaggagatccggcgtttctgcctcatgactctgcggaattttgggatggggaagaggagc
atcgaggaccgtgttcaagaggaagcccgctgccttgtggaggagttgagaaaaaccaat
gcctcaccctgtgatcccactttcatcctgggctgtgctccctgcaatgtgatctgctct
gttattttccatgatcgatttgattataaagatcagaggtttcttaacttgatggaaaaa
ttcaatgaaaacctcaggattctgagctctccatggatccaggtctgcaataatttccct
gctctcatcgattatctcccaggaagtcataataaaatagctgaaaattttgcttacatt
aaaagttatgtattggagagaataaaagaacatcaagaatccctggacatgaacagtgct
cgggactttattgattgtttcctgatcaaaatggaacaggaaaagcacaatcaacagtct
gaatttactgttgaaagcttgatagccactgtaactgatatgtttggggctggaacagag
acaacgagcaccactctgagatatggactcctgctcctgctgaagtacccagaggtcaca
gctaaagtccaggaagagattgaatgtgtagttggcagaaaccggagcccctgtatgcag
gacaggagtcacatgccctacacagatgctgtggtgcacgagatccagagatacattgac
ctcctccccaccaacctgccccatgcagtgacctgtgatgttaaattcaaaaactacctc
atccccaagggcacgaccataataacatccctgacttctgtgctgcacaatgacaaagaa
ttccccaacccagagatgtttgaccctggccactttctggataagagtggcaactttaag
aaaagtgactacttcatgcctttctcagcaggaaaacggatgtgtatgggagagggcctg
gcccgcatggagctgtttttattcctgaccaccattttgcagaactttaacctgaaatct
caggttgacccaaaggatattgacatcacccccattgccaatgcatttggtcgtgtgcca
cccttgtaccagctctgcttcattcctgtctga

All links

Pathway (6)   
   KEGG PATHWAY (6)   
Disease (1)   
   OMIM (1)   
Drug (2)   
   KEGG DRUG (2)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (12)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (6)   
   UNIGENE (1)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
Protein sequence (6)   
   UniProt (2)   
   RefSeq(pep) (2)   
   IPI (2)   
DNA sequence (14)   
   RefSeq(nuc) (2)   
   GenBank (6)   
   EMBL (6)   
Protein domain (2)   
   Pfam (1)   
   PROSITE (1)   
All databases (45)

DBGET integrated database retrieval system