KEGG H.sapiens: 159

Homo sapiens (human): 159

Entry

159 CDS H.sapiens

Gene name ADSS

Definition adenylosuccinate synthase (EC:6.3.4.4)

Orthology K01939 adenylosuccinate synthase [EC:6.3.4.4]

Pathway hsa00230 Purine metabolism
hsa00250 Alanine, aspartate and glutamate metabolism
hsa01100 Metabolic pathways

Class Metabolism; Nucleotide Metabolism; Purine metabolism [PATH:hsa00230]
Metabolism; Amino Acid Metabolism; Alanine, aspartate and glutamate
metabolism [PATH:hsa00250]

SSDB

Motif Pfam: Adenylsucc_synt Spore_YpjB
PROSITE: ADENYLOSUCCIN_SYN_2 ADENYLOSUCCIN_SYN_1

Other DBs NCBI-GI: 34577063
NCBI-GeneID: 159
OMIM: 103060
HGNC: 292
HPRD: 00050
Ensembl: ENSG00000035687
UniProt: B1AQM5 P30520

Structure

PDB: 2V40

Position 1cen-q12

AA seq 456 aa
MAFAETYPAASSLPNGDCGRPRARPGGNRVTVVLGAQWGDEGKGKVVDLLAQDADIVCRC
QGGNNAGHTVVVDSVEYDFHLLPSGIINPNVTAFIGNGVVIHLPGLFEEAEKNVQKGKGL
EGWEKRLIISDRAHIVFDFHQAADGIQEQQRQEQAGKNLGTTKKGIGPVYSSKAARSGLR
MCDLVSDFDGFSERFKVLANQYKSIYPTLEIDIEGELQKLKGYMEKIKPMVRDGVYFLYE
ALHGPPKKILVEGANAALLDIDFGTYPFVTSSNCTVGGVCTGLGMPPQNVGEVYGVVKAY
TTRVGIGAFPTEQDNEIGELLQTRGREFGVTTGRKRRCGWLDLVLLKYAHMINGFTALAL
TKLDILDMFTEIKVGVAYKLDGEIIPHIPANQEVLNKVEVQYKTLPGWNTDISNARAFKE
LPVNAQNYVRFIEDELQIPVKWIGVGKSRESMIQLF

NT seq 1371 nt +upstreamnt +downstreamnt
atggcgttcgccgagacctacccggcggcatcctccctgcccaacggcgattgcggccgc
cccagggcgcggcccggaggaaaccgggtgacggtggtgctcggtgcgcagtggggcgac
gaaggcaaagggaaggtggtggacctgctggcgcaggacgccgacatcgtgtgccgctgc
cagggaggaaataatgctggccatacagttgttgtggattctgtggaatatgattttcat
ctcttacccagtggaataattaatccaaatgtcactgcattcattggaaatggtgtggta
attcatctacctggattgtttgaagaagcagagaaaaatgttcaaaaaggaaaaggacta
gaaggctgggaaaaaaggcttattatatctgacagagctcatattgtatttgattttcat
caagcagctgatggtatccaggaacaacagagacaagaacaagcaggaaaaaatttgggt
acaacaaaaaagggcattggcccagtttattcgtccaaagctgctcggagtggactcagg
atgtgcgaccttgtttctgactttgatggcttctctgagaggtttaaagttctagctaac
caatacaaatctatataccccactttggaaatagacattgaaggtgaattacaaaaactc
aagggttatatggaaaagattaaaccaatggtgagagatggagtttattttctatatgag
gccctacatggaccaccaaagaaaatcttggtagaaggtgcaaatgcagcactattagat
attgattttgggacttacccttttgtaacctcttcaaattgtactgttggaggtgtttgt
actggtttgggtatgccacctcaaaatgttggagaagtgtatggagttgtgaaagcttat
acaactagagttggtattggtgcctttcctacagagcaagacaatgaaattggagaatta
ttacaaacaaggggtagagagtttggtgtaactactggaaggaaaagaagatgtggctgg
ttggacctcgttttgctcaaatatgctcatatgatcaatggatttactgcgttggcactt
accaagttggatattttggacatgtttacggaaatcaaagttggagttgcttacaagtta
gatggtgaaatcatacctcatatcccagcaaaccaagaagtcttaaataaagttgaagtt
caatataagactctcccaggatggaacacagacatatcaaatgcaagggcgtttaaagaa
ctacctgttaatgcacaaaactatgttcgatttattgaagatgagcttcaaattccagtt
aagtggattggtgttggtaaatccagagaatctatgattcaactcttttaa

All links

Pathway (3)   
   KEGG PATHWAY (3)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (13)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (7)   
   UNIGENE (1)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
Protein sequence (5)   
   UniProt (2)   
   RefSeq(pep) (1)   
   IPI (2)   
DNA sequence (9)   
   RefSeq(nuc) (1)   
   GenBank (4)   
   EMBL (4)   
3D Structure (1)   
   PDB (1)   
Protein domain (4)   
   Pfam (2)   
   PROSITE (2)   
All databases (38)

DBGET integrated database retrieval system