KEGG H.sapiens: 1606

Homo sapiens (human): 1606

Entry

1606 CDS H.sapiens

Gene name DGKA

Definition diacylglycerol kinase, alpha 80kDa (EC:2.7.1.107)

Orthology K00901 diacylglycerol kinase [EC:2.7.1.107]

Pathway hsa00561 Glycerolipid metabolism
hsa00564 Glycerophospholipid metabolism
hsa01100 Metabolic pathways
hsa04070 Phosphatidylinositol signaling system

Class Metabolism; Lipid Metabolism; Glycerolipid metabolism
[PATH:hsa00561]
Metabolism; Lipid Metabolism; Glycerophospholipid metabolism
[PATH:hsa00564]
Environmental Information Processing; Signal Transduction;
Phosphatidylinositol signaling system [PATH:hsa04070]

SSDB

Motif Pfam: DAGK_acc DAGK_cat C1_1 efhand
PROSITE: EF_HAND_1 ZF_DAG_PE_1 EF_HAND_2 ZF_DAG_PE_2

Other DBs NCBI-GI: 31542504
NCBI-GeneID: 1606
OMIM: 125855
HGNC: 2849
HPRD: 00517
Ensembl: ENSG00000065357
UniProt: P23743

Structure

PDB: 1TUZ

Position 12q13.3

AA seq 735 aa
MAKERGLISPSDFAQLQKYMEYSTKKVSDVLKLFEDGEMAKYVQGDAIGYEGFQQFLKIY
LEVDNVPRHLSLALFQSFETGHCLNETNVTKDVVCLNDVSCYFSLLEGGRPEDKLEFTFK
LYDTDRNGILDSSEVDKIILQMMRVAEYLDWDVSELRPILQEMMKEIDYDGSGSVSQAEW
VRAGATTVPLLVLLGLEMTLKDDGQHMWRPKRFPRPVYCNLCESSIGLGKQGLSCNLCKY
TVHDQCAMKALPCEVSTYAKSRKDIGVQSHVWVRGGCESGRCDRCQKKIRIYHSLTGLHC
VWCHLEIHDDCLQAVGHECDCGLLRDHILPPSSIYPSVLASGPDRKNSKTSQKTMDDLNL
STSEALRIDPVPNTHPLLVFVNPKSGGKQGQRVLWKFQYILNPRQVFNLLKDGPEIGLRL
FKDVPDSRILVCGGDGTVGWILETIDKANLPVLPPVAVLPLGTGNDLARCLRWGGGYEGQ
NLAKILKDLEMSKVVHMDRWSVEVIPQQTEEKSDPVPFQIINNYFSIGVDASIAHRFHIM
REKYPEKFNSRMKNKLWYFEFATSESIFSTCKKLEESLTVEICGKPLDLSNLSLEGIAVL
NIPSMHGGSNLWGDTRRPHGDIYGINQALGATAKVITDPDILKTCVPDLSDKRLEVVGLE
GAIEMGQIYTKLKNAGRRLAKCSEITFHTTKTLPMQIDGEPWMQTPCTIKITHKNQMPML
MGPPPRSTNFFGFLS

NT seq 2208 nt +upstreamnt +downstreamnt
atggccaaggagaggggcctaataagccccagtgattttgcccagctgcaaaaatacatg
gaatactccaccaaaaaggtcagtgatgtcctaaagctcttcgaggatggcgagatggct
aaatatgtccaaggagatgccattgggtacgagggattccagcaattcctgaaaatctat
ctcgaagtggataatgttcccagacacctaagcctggcactgtttcaatcctttgagact
ggtcactgcttaaatgagacaaatgtgacaaaagatgtggtgtgtctcaatgatgtttcc
tgctacttttcccttctggagggtggtcggccagaagacaagttagaattcaccttcaag
ctgtacgacacggacagaaatgggatcctggacagctcagaagtggacaaaattatccta
cagatgatgcgagtggctgaatacctggattgggatgtgtctgagctgaggccgattctt
caggagatgatgaaagagattgactatgatggcagtggctctgtctctcaagctgagtgg
gtccgggctggggccaccaccgtgccactgctagtgctgctgggtctggagatgactctg
aaggacgacggacagcacatgtggaggcccaagaggttccccagaccagtctactgcaat
ctgtgcgagtcaagcattggtcttggcaaacagggactgagctgtaacctctgtaagtac
actgttcacgaccagtgtgccatgaaagccctgccttgtgaagtcagcacctatgccaag
tctcggaaggacattggtgtccaatcacatgtgtgggtgcgaggaggctgtgagtccggg
cgctgcgaccgctgtcagaaaaagatccggatctaccacagtctgaccgggctgcattgt
gtatggtgccacctagagatccacgatgactgcctgcaagcggtgggccatgagtgtgac
tgtgggctgctccgggatcacatcctgcctccatcttccatctatcccagtgtcctggcc
tctggaccggatcgtaaaaatagcaaaacaagccagaagaccatggatgatttaaatttg
agcacctctgaggctctgcggattgaccctgttcctaacacccacccacttctcgtcttt
gtcaatcctaagagtggcgggaagcaggggcaaagggtgctctggaagttccagtatata
ttaaaccctcgacaggtgttcaacctcctaaaggatggtcctgagatagggctccgatta
ttcaaggatgttcctgatagccggattttggtgtgtggtggagacggcacagtaggctgg
attctagagaccattgacaaagctaacttgccagttttgcctcctgttgctgtgttgccc
ctgggtactggaaatgatctggctcgatgcctaagatggggaggaggttatgaaggacag
aatctggcaaagatcctcaaggatttagagatgagtaaagtggtacatatggatcgatgg
tctgtggaggtgatacctcaacaaactgaagaaaaaagtgacccagtcccctttcaaatc
atcaataactacttctctattggcgtggatgcctctattgctcatcgattccacatcatg
cgagagaaatatccggagaagttcaacagcagaatgaagaacaagctatggtacttcgaa
tttgccacatctgaatccatcttctcaacatgcaaaaagctggaggagtctttgacagtt
gagatctgtgggaaaccgctggatctgagcaacctgtccctagaaggcatcgcagtgcta
aacatccctagcatgcatggtggctccaacctctggggtgataccaggagaccccatggg
gatatctatgggatcaaccaggccttaggtgctacagctaaagtcatcaccgaccctgat
atcctgaaaacctgtgtaccagacctaagtgacaagagactggaagtggttgggctggag
ggtgcaattgagatgggccaaatctataccaagctcaagaatgctggacgtcggctggcc
aagtgctctgagatcaccttccacaccacaaaaacccttcccatgcaaattgacggagaa
ccctggatgcagacgccctgtacaatcaagatcacccacaagaaccagatgcccatgctc
atgggcccacccccccgctccaccaatttctttggcttcttgagctaa

All links

Pathway (4)   
   KEGG PATHWAY (4)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (10)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (4)   
   UNIGENE (1)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
Protein sequence (11)   
   UniProt (1)   
   RefSeq(pep) (4)   
   IPI (6)   
DNA sequence (8)   
   RefSeq(nuc) (4)   
   GenBank (2)   
   EMBL (2)   
3D Structure (1)   
   PDB (1)   
Protein domain (8)   
   Pfam (4)   
   PROSITE (4)   
All databases (45)

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