KEGG H.sapiens: 212

Homo sapiens (human): 212

Entry

212 CDS H.sapiens

Gene name ALAS2

Definition aminolevulinate, delta-, synthase 2 (EC:2.3.1.37)

Orthology K00643 5-aminolevulinate synthase [EC:2.3.1.37]

Pathway hsa00260 Glycine, serine and threonine metabolism
hsa00860 Porphyrin and chlorophyll metabolism
hsa01100 Metabolic pathways

Class Metabolism; Amino Acid Metabolism; Glycine, serine and threonine
metabolism [PATH:hsa00260]
Metabolism; Metabolism of Cofactors and Vitamins; Porphyrin and
chlorophyll metabolism [PATH:hsa00860]

SSDB

Motif Pfam: Aminotran_1_2 Preseq_ALAS Aminotran_5 Cys_Met_Meta_PP
DegT_DnrJ_EryC1
PROSITE: AA_TRANSFER_CLASS_2

Other DBs NCBI-GI: 83977442
NCBI-GeneID: 212
OMIM: 301300
HGNC: 397
HPRD: 02356
Ensembl: ENSG00000158578
UniProt: A8K3F0 P22557

Position Xp11.21

AA seq 587 aa
MVTAAMLLQCCPVLARGPTSLLGKVVKTHQFLFGIGRCPILATQGPNCSQIHLKATKAGG
DSPSWAKGHCPFMLSELQDGKSKIVQKAAPEVQEDVKAFKTDLPSSLVSVSLRKPFSGPQ
EQEQISGKVTHLIQNNMPGNYVFSYDQFFRDKIMEKKQDHTYRVFKTVNRWADAYPFAQH
FSEASVASKDVSVWCSNDYLGMSRHPQVLQATQETLQRHGAGAGGTRNISGTSKFHVELE
QELAELHQKDSALLFSSCFVANDSTLFTLAKILPGCEIYSDAGNHASMIQGIRNSGAAKF
VFRHNDPDHLKKLLEKSNPKIPKIVAFETVHSMDGAICPLEELCDVSHQYGALTFVDEVH
AVGLYGSRGAGIGERDGIMHKIDIISGTLGKAFGCVGGYIASTRDLVDMVRSYAAGFIFT
TSLPPMVLSGALESVRLLKGEEGQALRRAHQRNVKHMRQLLMDRGLPVIPCPSHIIPIRV
GNAALNSKLCDLLLSKHGIYVQAINYPTVPRGEELLRLAPSPHHSPQMMEDFVEKLLLAW
TAVGLPLQDVSVAACNFCRRPVHFELMSEWERSYFGNMGPQYVTTYA

NT seq 1764 nt +upstreamnt +downstreamnt
atggtgactgcagccatgctgctacagtgctgcccagtgcttgcccggggccccacaagc
ctcctaggcaaggtggttaagactcaccagttcctgtttggtattggacgctgtcccatc
ctggctacccaaggaccaaactgttctcaaatccaccttaaggcaacaaaggctggagga
gattctccatcttgggcgaagggccactgtcccttcatgctgtcggaactccaggatggg
aagagcaagattgtgcagaaggcagccccagaagtccaggaagatgtgaaggctttcaag
acagatctgcctagctccctggtctcagtcagcctaaggaagccattttccggtccccag
gagcaggagcagatctctgggaaggtcacacacctgattcagaacaatatgcctggaaac
tatgtcttcagttatgaccagtttttcagggacaagatcatggagaagaaacaggatcac
acctaccgtgtgttcaagactgtgaaccgctgggctgatgcatatccctttgcccaacat
ttctctgaggcatctgtggcctcaaaggatgtgtccgtctggtgtagtaatgattacctg
ggcatgagccgacaccctcaggtcttgcaagccacacaggagaccctgcagcgtcatggt
gctggagctggtggcacccgcaacatctcaggcaccagtaagtttcatgtggagcttgag
caggagctggctgagctgcaccagaaggactcagccctgctcttctcctcctgctttgtt
gccaatgactctactctcttcaccttggccaagatcctgccagggtgcgagatttactca
gacgcaggcaaccatgcttccatgatccaaggtatccgtaacagtggagcagccaagttt
gtcttcaggcacaatgaccctgaccacctaaagaaacttctagagaagtctaaccctaag
atacccaaaattgtggcctttgagactgtccactccatggatggtgccatctgtcccctc
gaggagttgtgtgatgtgtcccaccagtatggggccctgaccttcgtggatgaggtccat
gctgtaggactgtatgggtcccggggcgctgggattggggagcgtgatggaattatgcat
aagattgacatcatctctggaactcttggcaaggcctttggctgtgtgggcggctacatt
gccagcacccgtgacttggtggacatggtgcgctcctatgctgcaggcttcatctttacc
acttctctgccccccatggtgctctctggagctctagaatctgtgcggctgctcaaggga
gaggagggccaagccctgaggcgagcccaccagcgcaatgtcaagcacatgcgccagcta
ctcatggacaggggccttcctgtcatcccctgccccagccacatcatccccatccgggtg
ggcaatgcagcactcaacagcaagctctgtgatctcctgctctccaagcatggcatctat
gtgcaggccatcaactacccaactgtcccccggggtgaagagctcctgcgcttggcaccc
tccccccaccacagccctcagatgatggaagattttgtggagaagctgctgctggcttgg
actgcggtggggctgcccctccaggatgtgtctgtggctgcctgcaatttctgtcgccgt
cctgtacactttgagctcatgagtgagtgggaacgttcctacttcgggaacatggggccc
cagtatgtcaccacctatgcctga

All links

Pathway (3)   
   KEGG PATHWAY (3)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (54)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (47)   
   UNIGENE (2)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
Protein sequence (9)   
   UniProt (2)   
   RefSeq(pep) (3)   
   IPI (4)   
DNA sequence (93)   
   RefSeq(nuc) (3)   
   GenBank (45)   
   EMBL (45)   
Protein domain (6)   
   Pfam (5)   
   PROSITE (1)   
All databases (168)

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