KEGG   Homo sapiens (human): 214
Entry
214               CDS       T01001                                 
Symbol
ALCAM, CD166, MEMD
Name
(RefSeq) activated leukocyte cell adhesion molecule
  KO
K06547  activated leukocyte cell adhesion molecule
Organism
hsa  Homo sapiens (human)
Pathway
hsa04514  Cell adhesion molecules
Drug target
Praluzatamab: D11959
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04514 Cell adhesion molecules
    214 (ALCAM)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04515 Cell adhesion molecules [BR:hsa04515]
    214 (ALCAM)
   04090 CD molecules [BR:hsa04090]
    214 (ALCAM)
Cell adhesion molecules [BR:hsa04515]
 Immunoglobulin superfamily
  ALCAM
   214 (ALCAM)
CD molecules [BR:hsa04090]
 Proteins
  214 (ALCAM)
SSDB
Motif
Pfam: Ig_3 C2-set_2 Ig_2 I-set ig C1-set V-set DUF6377 Podoplanin FixQ Amnionless PepSY_TM FeoB_associated
Other DBs
NCBI-GeneID: 214
NCBI-ProteinID: NP_001618
OMIM: 601662
HGNC: 400
Ensembl: ENSG00000170017
UniProt: Q13740
Structure
Position
3:105366909..105576900
AA seq 583 aa
MESKGASSCRLLFCLLISATVFRPGLGWYTVNSAYGDTIIIPCRLDVPQNLMFGKWKYEK
PDGSPVFIAFRSSTKKSVQYDDVPEYKDRLNLSENYTLSISNARISDEKRFVCMLVTEDN
VFEAPTIVKVFKQPSKPEIVSKALFLETEQLKKLGDCISEDSYPDGNITWYRNGKVLHPL
EGAVVIIFKKEMDPVTQLYTMTSTLEYKTTKADIQMPFTCSVTYYGPSGQKTIHSEQAVF
DIYYPTEQVTIQVLPPKNAIKEGDNITLKCLGNGNPPPEEFLFYLPGQPEGIRSSNTYTL
TDVRRNATGDYKCSLIDKKSMIASTAITVHYLDLSLNPSGEVTRQIGDALPVSCTISASR
NATVVWMKDNIRLRSSPSFSSLHYQDAGNYVCETALQEVEGLKKRESLTLIVEGKPQIKM
TKKTDPSGLSKTIICHVEGFPKPAIQWTITGSGSVINQTEESPYINGRYYSKIIISPEEN
VTLTCTAENQLERTVNSLNVSAISIPEHDEADEISDENREKVNDQAKLIVGIVVGLLLAA
LVAGVVYWLYMKKSKTASKHVNKDLGNMEENKKLEENNHKTEA
NT seq 1752 nt   +upstreamnt  +downstreamnt
atggaatccaagggggccagttcctgccgtctgctcttctgcctcttgatctccgccacc
gtcttcaggccaggccttggatggtatactgtaaattcagcatatggagataccattatc
ataccttgccgacttgacgtacctcagaatctcatgtttggcaaatggaaatatgaaaag
cccgatggctccccagtatttattgccttcagatcctctacaaagaaaagtgtgcagtac
gacgatgtaccagaatacaaagacagattgaacctctcagaaaactacactttgtctatc
agtaatgcaaggatcagtgatgaaaagagatttgtgtgcatgctagtaactgaggacaac
gtgtttgaggcacctacaatagtcaaggtgttcaagcaaccatctaaacctgaaattgta
agcaaagcactgtttctcgaaacagagcagctaaaaaagttgggtgactgcatttcagaa
gacagttatccagatggcaatatcacatggtacaggaatggaaaagtgctacatcccctt
gaaggagcggtggtcataatttttaaaaaggaaatggacccagtgactcagctctatacc
atgacttccaccctggagtacaagacaaccaaggctgacatacaaatgccattcacctgc
tcggtgacatattatggaccatctggccagaaaacaattcattctgaacaggcagtattt
gatatttactatcctacagagcaggtgacaatacaagtgctgccaccaaaaaatgccatc
aaagaaggggataacatcactcttaaatgcttagggaatggcaaccctcccccagaggaa
tttttgttttacttaccaggacagcccgaaggaataagaagctcaaatacttacacactg
acggatgtgaggcgcaatgcaacaggagactacaagtgttccctgatagacaaaaaaagc
atgattgcttcaacagctatcacagttcactatttggatttgtccttaaacccaagtgga
gaagtgactagacagattggtgatgccctacccgtgtcatgcacaatatctgctagcagg
aatgcaactgtggtatggatgaaagataacatcaggcttcgatctagcccgtcattttct
agtcttcattatcaggatgctggaaactatgtctgcgaaactgctctgcaggaggttgaa
ggactaaagaaaagagagtcattgactctcattgtagaaggcaaacctcaaataaaaatg
acaaagaaaactgatcccagtggactatctaaaacaataatctgccatgtggaaggtttt
ccaaagccagccattcaatggacaattactggcagtggaagcgtcataaaccaaacagag
gaatctccttatattaatggcaggtattatagtaaaattatcatttcccctgaagagaat
gttacattaacttgcacagcagaaaaccaactggagagaacagtaaactccttgaatgtc
tctgctataagtattccagaacacgatgaggcagacgagataagtgatgaaaacagagaa
aaggtgaatgaccaggcaaaactaattgtgggaatcgttgttggtctcctccttgctgcc
cttgttgctggtgtcgtctactggctgtacatgaagaagtcaaagactgcatcaaaacat
gtaaacaaggacctcggtaatatggaagaaaacaaaaagttagaagaaaacaatcacaaa
actgaagcctaa

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (1)   
   OMIM (1)   
Drug (1)   
   KEGG DRUG (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (12)   
   KEGG ORTHOLOGY (1)   
   RefGene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (4)   
   OC (1)   
Protein sequence (6)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (4)   
DNA sequence (48)   
   RefSeq(nuc) (4)   
   GenBank (22)   
   EMBL (22)   
3D Structure (1)   
   PDB (1)   
Protein domain (13)   
   Pfam (13)   
All databases (87)   

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