KEGG T01001: 2213

Homo sapiens (human): 2213

Entry

2213 CDS T01001

Gene name

FCGR2B, CD32, CD32B, FCG2, FCGR2, IGFR2

Definition

Fc fragment of IgG, low affinity IIb, receptor (CD32)

Orthology

K12560

low affinity immunoglobulin gamma Fc region receptor II-b

Organism

hsa Homo sapiens (human)

Pathway

hsa04145	Phagosome
hsa04380	Osteoclast differentiation
hsa04662	B cell receptor signaling pathway
hsa04666	Fc gamma R-mediated phagocytosis
hsa05150	Staphylococcus aureus infection
hsa05152	Tuberculosis
hsa05162	Measles

Disease

H00080

Systemic lupus erythematosus

Class

Cellular Processes; Transport and catabolism; Phagosome [PATH:hsa04145]
Organismal Systems; Immune system; B cell receptor signaling pathway [PATH:hsa04662]
Organismal Systems; Immune system; Fc gamma R-mediated phagocytosis [PATH:hsa04666]
Organismal Systems; Development; Osteoclast differentiation [PATH:hsa04380]
Human Diseases; Infectious diseases; Staphylococcus aureus infection [PATH:hsa05150]
Human Diseases; Infectious diseases; Tuberculosis [PATH:hsa05152]
Human Diseases; Infectious diseases; Measles [PATH:hsa05162]

SSDB

Motif

Pfam:

Ig_2 Ig_3 I-set ig V-set Herpes_gE V-set_CD47 DUF1191 Adeno_E3_CR2

Other DBs

NCBI-GI:

NCBI-GeneID:

OMIM:

HGNC:

HPRD:

Ensembl:

Vega:

UniProt:

Structure

PDB:

2FCB

Position

1q23

AA seq 290 aa
MGILSFLPVLATESDWADCKSPQPWGHMLLWTAVLFLAPVAGTPAPPKAVLKLEPQWINV
LQEDSVTLTCRGTHSPESDSIQWFHNGNLIPTHTQPSYRFKANNNDSGEYTCQTGQTSLS
DPVHLTVLSEWLVLQTPHLEFQEGETIVLRCHSWKDKPLVKVTFFQNGKSKKFSRSDPNF
SIPQANHSHSGDYHCTGNIGYTLYSSKPVTITVQAPSSSPMGIIVAVVTGIAVAAIVAAV
VALIYCRKKRISANPTNPDEADKVGAENTITYSLLMHPDALEEPDDQNRI

NT seq 873 nt +upstreamnt +downstreamnt
atgggaatcctgtcattcttacctgtccttgccactgagagtgactgggctgactgcaag
tccccccagccttggggtcatatgcttctgtggacagctgtgctattcctggctcctgtt
gctgggacacctgctcccccaaaggctgtgctgaaactcgagccccagtggatcaacgtg
ctccaggaggactctgtgactctgacatgccgggggactcacagccctgagagcgactcc
attcagtggttccacaatgggaatctcattcccacccacacgcagcccagctacaggttc
aaggccaacaacaatgacagcggggagtacacgtgccagactggccagaccagcctcagc
gaccctgtgcatctgactgtgctttctgagtggctggtgctccagacccctcacctggag
ttccaggagggagaaaccatcgtgctgaggtgccacagctggaaggacaagcctctggtc
aaggtcacattcttccagaatggaaaatccaagaaattttcccgttcggatcccaacttc
tccatcccacaagcaaaccacagtcacagtggtgattaccactgcacaggaaacataggc
tacacgctgtactcatccaagcctgtgaccatcactgtccaagctcccagctcttcaccg
atggggatcattgtggctgtggtcactgggattgctgtagcggccattgttgctgctgta
gtggccttgatctactgcaggaaaaagcggatttcagccaatcccactaatcctgatgag
gctgacaaagttggggctgagaacacaatcacctattcacttctcatgcacccggatgct
ctggaagagcctgatgaccagaaccgtatttag

All links

Ontology (2)   
   KEGG BRITE (2)   
Pathway (7)   
   KEGG PATHWAY (7)   
Disease (4)   
   KEGG DISEASE (1)   
   OMIM (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (43)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (35)   
   UniGene (1)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
   OC (1)   
   VEGA (1)   
Protein sequence (6)   
   UniProt (1)   
   RefSeq(pep) (5)   
DNA sequence (87)   
   RefSeq(nuc) (5)   
   GenBank (41)   
   EMBL (41)   
3D Structure (1)   
   PDB (1)   
Protein domain (9)   
   Pfam (9)   
All databases (160)   

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