KEGG H.sapiens: 2222

Homo sapiens (human): 2222

Entry

2222 CDS H.sapiens

Gene name FDFT1

Definition farnesyl-diphosphate farnesyltransferase 1 (EC:2.5.1.21)

Orthology K00801 farnesyl-diphosphate farnesyltransferase [EC:2.5.1.21]

Pathway hsa00100 Steroid biosynthesis
hsa01100 Metabolic pathways

Class Metabolism; Lipid Metabolism; Steroid biosynthesis [PATH:hsa00100]

SSDB

Motif Pfam: SQS_PSY
PROSITE: SQUALEN_PHYTOEN_SYN_2 SQUALEN_PHYTOEN_SYN_1

Other DBs NCBI-GI: 67089147
NCBI-GeneID: 2222
OMIM: 184420
HGNC: 3629
HPRD: 01694
Ensembl: ENSG00000079459
UniProt: P37268 Q6IAX1

Structure

PDB: 1EZF

Position 8p23.1-p22

AA seq 417 aa
MEFVKCLGHPEEFYNLVRFRIGGKRKVMPKMDQDSLSSSLKTCYKYLNQTSRSFAAVIQA
LDGEMRNAVCIFYLVLRALDTLEDDMTISVEKKVPLLHNFHSFLYQPDWRFMESKEKDRQ
VLEDFPTISLEFRNLAEKYQTVIADICRRMGIGMAEFLDKHVTSEQEWDKYCHYVAGLVG
IGLSRLFSASEFEDPLVGEDTERANSMGLFLQKTNIIRDYLEDQQGGREFWPQEVWSRYV
KKLGDFAKPENIDLAVQCLNELITNALHHIPDVITYLSRLRNQSVFNFCAIPQVMAIATL
AACYNNQQVFKGAVKIRKGQAVTLMMDATNMPAVKAIIYQYMEEIYHRIPDSDPSSSKTR
QIISTIRTQNLPNCQLISRSHYSPIYLSFVMLLAALSWQYLTTLSQVTEDYVQTGEH

NT seq 1254 nt +upstreamnt +downstreamnt
atggagttcgtgaaatgccttggccaccccgaagagttctacaacctggtgcgcttccgg
atcgggggcaagcggaaggtgatgcccaagatggaccaggactcgctcagcagcagcctg
aaaacttgctacaagtatctcaatcagaccagtcgcagtttcgcagctgttatccaggcg
ctggatggggaaatgcgcaacgcagtgtgcatattttatctggttctccgagctctggac
acactggaagatgacatgaccatcagtgtggaaaagaaggtcccgctgttacacaacttt
cactctttcctttaccaaccagactggcggttcatggagagcaaggagaaggatcgccag
gtgctggaggacttcccaacgatctcccttgagtttagaaatctggctgagaaataccaa
acagtgattgccgacatttgccggagaatgggcattgggatggcagagtttttggataag
catgtgacctctgaacaggagtgggacaagtactgccactatgttgctgggctggtcgga
attggcctttcccgtcttttctcagcctcagagtttgaagaccccttagttggtgaagat
acagaacgtgccaactctatgggcctgtttttgcagaaaacaaacatcatccgtgactat
ctggaagaccagcaaggaggaagagagttctggcctcaagaggtttggagcaggtatgtt
aagaagttaggggattttgctaagccggagaatattgacttggccgtgcagtgcctgaat
gaacttataaccaatgcactgcaccacatcccagatgtcatcacctacctttcgagactc
agaaaccagagtgtgtttaacttctgtgctattccacaggtgatggccattgccactttg
gctgcctgttataataaccagcaggtgttcaaaggggcagtgaagattcggaaagggcaa
gcagtgaccctgatgatggatgccaccaatatgccagctgtcaaagccatcatatatcag
tatatggaagagatttatcatagaatccccgactcagacccatcttctagcaaaacaagg
cagatcatctccaccatccggacgcagaatcttcccaactgtcagctgatttcccgaagc
cactactcccccatctacctgtcgtttgtcatgcttttggctgccctgagctggcagtac
ctgaccactctctcccaggtaacagaagactatgttcagactggagaacactga

All links

Pathway (2)   
   KEGG PATHWAY (2)   
Disease (1)   
   OMIM (1)   
Drug (3)   
   KEGG DRUG (3)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (9)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (3)   
   UNIGENE (1)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
Protein sequence (10)   
   UniProt (2)   
   RefSeq(pep) (1)   
   IPI (7)   
DNA sequence (9)   
   RefSeq(nuc) (1)   
   GenBank (4)   
   EMBL (4)   
3D Structure (1)   
   PDB (1)   
Protein domain (3)   
   Pfam (1)   
   PROSITE (2)   
All databases (40)

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