KEGG H.sapiens: 23395

Homo sapiens (human): 23395

Entry

23395 CDS H.sapiens

Gene name LARS2

Definition leucyl-tRNA synthetase 2, mitochondrial (EC:6.1.1.4)

Orthology K01869 leucyl-tRNA synthetase [EC:6.1.1.4]

Pathway hsa00290 Valine, leucine and isoleucine biosynthesis
hsa00970 Aminoacyl-tRNA biosynthesis

Class Metabolism; Amino Acid Metabolism; Valine, leucine and isoleucine
biosynthesis [PATH:hsa00290]
Genetic Information Processing; Translation; Aminoacyl-tRNA
biosynthesis [PATH:hsa00970]

SSDB

Motif Pfam: tRNA-synt_1 tRNA-synt_1g Anticodon_1 tRNA-synt_1e tRNA-synt_1d
tRNA-synt_1f
PROSITE: AA_TRNA_LIGASE_I

Other DBs NCBI-GI: 7661872
NCBI-GeneID: 23395
OMIM: 604544
HGNC: 17095
HPRD: 05178
Ensembl: ENSG00000011376
UniProt: Q15031

Position 3p21.3

AA seq 903 aa
MASVWQRLGFYASLLKRQLNGGPDVIKWERRVIPGCTRSIYSATGKWTKEYTLQTRKDVE
KWWHQRIKEQASKISEADKSKPKFYVLSMFPYPSGKLHMGHVRVYTISDTIARFQKMRGM
QVINPMGWDAFGLPAENAAVERNLHPQSWTQSNIKHMRKQLDRLGLCFSWDREITTCLPD
YYKWTQYLFIKLYEAGLAYQKEALVNWDPVDQTVLANEQVDEHGCSWRSGAKVEQKYLRQ
WFIKTTAYAKAMQDALADLPEWYGIKGMQAHWIGDCVGCHLDFTLKVHGQATGEKLTAYT
ATPEAIYGTSHVAISPSHRLLHGHSSLKEALRMALVPGKDCLTPVMAVNMLTQQEVPVVI
LAKADLEGSLDSKIGIPSTSSEDTILAQTLGLAYSEVIETLPDGTERLSSSAEFTGMTRQ
DAFLALTQKARGKRVGGDVTSDKLKDWLISRQRYWGTPIPIVHCPVCGPTPVPLEDLPVT
LPNIASFTGKGGPPLAMASEWVNCSCPRCKGAAKRETDTMDTFVDSAWYYFRYTDPHNPH
SPFNTAVADYWMPVDLYIGGKEHAVMHLFYARFFSHFCHDQKMVKHREPFHKLLAQGLIK
GQTFRLPSGQYLQREEVDLTGSVPVHAKTKEKLEVTWEKMSKSKHNGVDPEEVVEQYGID
TIRLYILFAAPPEKDILWDVKTDALPGVLRWQQRLWTLTTRFIEARASGKSPQPQLLSNK
EKAEARKLWEYKNSVISQVTTHFTEDFSLNSAISQLMGLSNALSQASQSVILHSPEFEDA
LCALMVMAAPLAPHVTSEIWAGLALVPRKLCAHYTWDASVLLQAWPAVDPEFLQQPEVVQ
MAVLINNKACGKIPVPQQVARDQDKVHEFVLQSELGVRLLQGRSIKKSFLSPRTALINFL
VQD

NT seq 2712 nt +upstreamnt +downstreamnt
atggcttctgtttggcagagattgggtttttatgcctctcttctgaaaagacagctaaat
ggtgggccagatgtcatcaagtgggaaaggagagtaattcccggatgtaccagaagcatc
tacagtgccacgggaaagtggacaaaagagtatacattgcagacaagaaaggatgttgag
aaatggtggcatcaacgaataaaagaacaggcctccaaaatttcagaagctgataaatcg
aagccaaaattttacgtgctttccatgttcccttatccttctggtaagctgcacatgggc
catgtgcgtgtctacaccatcagcgacaccatagcacggttccagaagatgagagggatg
caggtcatcaaccccatgggatgggatgcttttggattgcctgctgaaaatgccgcagtc
gagaggaatctacatccacaaagttggacacaaagtaatattaaacacatgaggaaacag
cttgatcgtctgggcctgtgtttcagctgggatagggaaataactacgtgtttgccagat
tactacaagtggactcagtatctctttattaaactgtatgaggctgggctggcctatcaa
aaggaggccctggttaactgggacccagtggatcaaacagtgcttgccaatgagcaggtg
gatgaacatggctgttcatggcgttctggagcaaaggtggaacagaagtacctcagacaa
tggtttattaagacaaccgcttatgcaaaggccatgcaggacgcgttggcagaccttcca
gaatggtatggaataaaaggcatgcaagcccactggattggggactgtgtgggctgccac
ctggacttcacattaaaggttcatgggcaagccacgggcgaaaagctgactgcctatacg
gccacccctgaagccatttatggcacctcccacgtggccatctcgcccagccacagactc
ctacatgggcacagctctctgaaggaagccttgaggatggcccttgtccctggcaaagat
tgcctcacgcctgtaatggctgtgaacatgcttacccagcaggaggtccctgtcgttatt
ttggccaaagctgacttggaaggctctctggattcaaaaataggaattcccagtactagc
tcagaggacaccatcttagcccaaaccctgggcctggcctactctgaagtcattgaaact
ttgccagatggcacagagagactgagcagctctgctgagttcacaggtatgacccggcag
gatgcttttctagccctgactcagaaagcccgggggaagagagtgggtggagacgtgaca
agtgataaactgaaagactggctgatttcacggcagcggtactggggcacaccaatcccc
attgtccactgcccagtctgtggccccacacctgtgcccctggaggacttgcctgtgacc
ctgcccaacatcgcgtctttcactggcaagggaggccccccactggccatggcttcagag
tgggtgaactgctcctgcccaaggtgcaagggagcagccaagagagagacagacacgatg
gatacctttgttgattctgcttggtactacttcagatacactgaccctcataatccacac
agcccttttaacacagcagtggccgattactggatgcctgtggatttgtacattggaggg
aaagaacatgccgtcatgcacttgttctatgcaagattctttagtcatttttgccatgat
caaaaaatggttaaacatagggagccttttcataagctgctggcccaaggccttatcaag
gggcagacattccgcctaccatctggacagtatctacagagagaggaagtggatctcaca
ggttccgttcctgttcatgcaaaaacgaaagagaagttagaggtgacgtgggagaagatg
agtaagtccaaacacaacggggtggacccagaggaagttgtggagcagtatgggatcgac
acgattcggctctacatcctttttgctgcccctcctgagaaggatatcttgtgggatgtg
aaaactgatgctctccctggggtgctgagatggcaacaacgactgtggaccttgacaact
cggtttattgaggccagggcttctgggaagtctccccagcctcagctgctgagtaacaag
gagaaagctgaggccaggaagctctgggagtacaagaactccgtcatctctcaggtgacc
acccatttcacagaggacttctcactgaattctgcaatttctcagctgatgggactcagc
aatgccctctcgcaagcctctcagagcgtcattctccacagccccgagtttgaggatgct
ttgtgtgccctgatggtaatggctgctccactggcccctcatgtaacctcagagatctgg
gcaggcctggcgctggtgccgaggaagctctgtgcccactacacttgggatgccagtgtg
ctgctccaggcatggcctgctgtggacccggagttcctgcagcagcctgaggttgtccag
atggcagttctgatcaacaataaagcttgtggcaaaattcctgtgccccaacaagttgcc
cgggaccaggacaaagtccacgaatttgttcttcaaagcgagctgggtgtcaggcttttg
caaggacgaagcatcaagaagtccttcctttccccgagaactgccctcatcaacttcctg
gtgcaagattga

All links

Pathway (2)   
   KEGG PATHWAY (2)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (9)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (3)   
   UNIGENE (1)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
Protein sequence (7)   
   UniProt (1)   
   RefSeq(pep) (1)   
   IPI (5)   
DNA sequence (11)   
   RefSeq(nuc) (1)   
   GenBank (5)   
   EMBL (5)   
Protein domain (7)   
   Pfam (6)   
   PROSITE (1)   
All databases (39)

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