KEGG H.sapiens: 2539

Homo sapiens (human): 2539

Entry

2539 CDS H.sapiens

Gene name G6PD

Definition glucose-6-phosphate dehydrogenase (EC:1.1.1.49)

Orthology K00036 glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49]

Pathway hsa00030 Pentose phosphate pathway
hsa00480 Glutathione metabolism
hsa01100 Metabolic pathways

Disease H00101 Other phagocyte defects

Class Metabolism; Carbohydrate Metabolism; Pentose phosphate pathway
[PATH:hsa00030]
Metabolism; Metabolism of Other Amino Acids; Glutathione metabolism
[PATH:hsa00480]

SSDB

Motif Pfam: G6PD_C G6PD_N
PROSITE: G6P_DEHYDROGENASE

Other DBs NCBI-GI: 109389365
NCBI-GeneID: 2539
OMIM: 305900
HGNC: 4057
HPRD: 02377
Ensembl: ENSG00000160211
UniProt: P11413

Structure

PDB: 2BHL 2BH9 1QKI

Position Xq28

AA seq 545 aa
MGRRGSAPGNGRTLRGCERGGRRRRSADSVMAEQVALSRTQVCGILREELFQGDAFHQSD
THIFIIMGASGDLAKKKIYPTIWWLFRDGLLPENTFIVGYARSRLTVADIRKQSEPFFKA
TPEEKLKLEDFFARNSYVAGQYDDAASYQRLNSHMNALHLGSQANRLFYLALPPTVYEAV
TKNIHESCMSQIGWNRIIVEKPFGRDLQSSDRLSNHISSLFREDQIYRIDHYLGKEMVQN
LMVLRFANRIFGPIWNRDNIACVILTFKEPFGTEGRGGYFDEFGIIRDVMQNHLLQMLCL
VAMEKPASTNSDDVRDEKVKVLKCISEVQANNVVLGQYVGNPDGEGEATKGYLDDPTVPR
GSTTATFAAVVLYVENERWDGVPFILRCGKALNERKAEVRLQFHDVAGDIFHQQCKRNEL
VIRVQPNEAVYTKMMTKKPGMFFNPEESELDLTYGNRYKNVKLPDAYERLILDVFCGSQM
HFVRSDELREAWRIFTPLLHQIELEKPKPIPYIYGSRGPTEADELMKRVGFQYEGTYKWV
NPHKL

NT seq 1638 nt +upstreamnt +downstreamnt
atgggccggcggggctcagcccccggaaacggtcgtacacttcggggctgcgagcgcgga
gggcgacgacgacgaagcgcagacagcgtcatggcagagcaggtggccctgagccggacc
caggtgtgcgggatcctgcgggaagagcttttccagggcgatgccttccatcagtcggat
acacacatattcatcatcatgggtgcatcgggtgacctggccaagaagaagatctacccc
accatctggtggctgttccgggatggccttctgcccgaaaacaccttcatcgtgggctat
gcccgttcccgcctcacagtggctgacatccgcaaacagagtgagcccttcttcaaggcc
accccagaggagaagctcaagctggaggacttctttgcccgcaactcctatgtggctggc
cagtacgatgatgcagcctcctaccagcgcctcaacagccacatgaatgccctccacctg
gggtcacaggccaaccgcctcttctacctggccttgcccccgaccgtctacgaggccgtc
accaagaacattcacgagtcctgcatgagccagataggctggaaccgcatcatcgtggag
aagcccttcgggagggacctgcagagctctgaccggctgtccaaccacatctcctccctg
ttccgtgaggaccagatctaccgcatcgaccactacctgggcaaggagatggtgcagaac
ctcatggtgctgagatttgccaacaggatcttcggccccatctggaaccgggacaacatc
gcctgcgttatcctcaccttcaaggagccctttggcactgagggtcgcgggggctatttc
gatgaatttgggatcatccgggacgtgatgcagaaccacctactgcagatgctgtgtctg
gtggccatggagaagcccgcctccaccaactcagatgacgtccgtgatgagaaggtcaag
gtgttgaaatgcatctcagaggtgcaggccaacaatgtggtcctgggccagtacgtgggg
aaccccgatggagagggcgaggccaccaaagggtacctggacgaccccacggtgccccgc
gggtccaccaccgccacttttgcagccgtcgtcctctatgtggagaatgagaggtgggat
ggggtgcccttcatcctgcgctgcggcaaggccctgaacgagcgcaaggccgaggtgagg
ctgcagttccatgatgtggccggcgacatcttccaccagcagtgcaagcgcaacgagctg
gtgatccgcgtgcagcccaacgaggccgtgtacaccaagatgatgaccaagaagccgggc
atgttcttcaaccccgaggagtcggagctggacctgacctacggcaacagatacaagaac
gtgaagctccctgacgcctacgagcgcctcatcctggacgtcttctgcgggagccagatg
cacttcgtgcgcagcgacgagctccgtgaggcctggcgtattttcaccccactgctgcac
cagattgagctggagaagcccaagcccatcccctatatttatggcagccgaggccccacg
gaggcagacgagctgatgaagagagtgggtttccagtatgagggcacctacaagtgggtg
aacccccacaagctctga

All links

Pathway (3)   
   KEGG PATHWAY (3)   
Disease (2)   
   KEGG DISEASE (1)   
   OMIM (1)   
Drug (3)   
   KEGG DRUG (3)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (121)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (114)   
   UNIGENE (2)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
Protein sequence (9)   
   UniProt (1)   
   RefSeq(pep) (2)   
   IPI (6)   
DNA sequence (218)   
   RefSeq(nuc) (2)   
   GenBank (108)   
   EMBL (108)   
3D Structure (3)   
   PDB (3)   
Protein domain (3)   
   Pfam (2)   
   PROSITE (1)   
All databases (364)

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