KEGG   Homo sapiens (human): 2582Help
Entry
2582              CDS       H.sapiens                              
Gene name GALE
Definition UDP-galactose-4-epimerase (EC:5.1.3.2)
Orthology K01784  UDP-glucose 4-epimerase [EC:5.1.3.2]
Pathway hsa00052  Galactose metabolism
hsa00520  Amino sugar and nucleotide sugar metabolism
hsa01100  Metabolic pathways
Disease H00070  Galactosemia
Class Metabolism; Carbohydrate Metabolism; Galactose metabolism
[PATH:hsa00052]
Metabolism; Carbohydrate Metabolism; Amino sugar and nucleotide
sugar metabolism [PATH:hsa00520]
BRITE hierarchy
SSDB OrthologParalogGene clusterGFIT
Motif Pfam: Epimerase 3Beta_HSD RmlD_sub_bind Polysacc_synt_2 adh_short
      NAD_binding_4 KR NmrA
Motif
Other DBs NCBI-GI: 56237023
NCBI-GeneID: 2582
OMIM: 606953
HGNC: 4116
HPRD: 06092
Ensembl: ENSG00000117308
UniProt: Q14376 Q38G75
Structure
PDB: 1I3K 1I3L 1I3M 1I3N 1HZJ 1EK6 1EK5
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Jmol
Position 1p36-p35
AA seq 348 aa AA seqDB search
MAEKVLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSV
EFEEMDILDQGALQRLFKKYSFMAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMK
AHGVKNLVFSSSATVYGNPQYLPLDEAHPTGGCTNPYGKSKFFIEEMIRDLCQADKTWNA
VLLRYFNPTGAHASGCIGEDPQGIPNNLMPYVSQVAIGRREALNVFGNDYDTEDGTGVRD
YIHVVDLAKGHIAALRKLKEQCGCRIYNLGTGTGYSVLQMVQAMEKASGKKIPYKVVARR
EGDVAACYANPSLAQEELGWTAALGLDRMCEDLWRWQKQNPSGFGTQA
NT seq 1047 nt NT seq  +upstreamnt  +downstreamnt
atggcagagaaggtgctggtaacaggtggggctggctacattggcagccacacggtgctg
gagctgctggaggctggctacttgcctgtggtcatcgataacttccataatgccttccgt
ggagggggctccctgcctgagagcctgcggcgggtccaggagctgacaggccgctctgtg
gagtttgaggagatggacattttggaccagggagccctacagcgtctcttcaaaaagtac
agctttatggcggtcatccactttgcggggctcaaggccgtgggcgagtcggtgcagaag
cctctggattattacagagttaacctgaccgggaccatccagcttctggagatcatgaag
gcccacggggtgaagaacctggtgttcagcagctcagccactgtgtacgggaacccccag
tacctgccccttgatgaggcccaccccacgggtggttgtaccaacccttacggcaagtcc
aagttcttcatcgaggaaatgatccgggacctgtgccaggcagacaagacttggaacgca
gtgctgctgcgctatttcaaccccacaggtgcccatgcctctggctgcattggtgaggat
ccccagggcatacccaacaacctcatgccttatgtctcccaggtggcgatcgggcgacgg
gaggccctgaatgtctttggcaatgactatgacacagaggatggcacaggtgtccgggat
tacatccatgtcgtggatctggccaagggccacattgcagccttaaggaagctgaaagaa
cagtgtggctgccggatctacaacctgggcacgggcacaggctattcagtgctgcagatg
gtccaggctatggagaaggcctctgggaagaagatcccgtacaaggtggtggcacggcgg
gaaggtgatgtggcagcctgttacgccaaccccagcctggcccaagaggagctggggtgg
acagcagccttagggctggacaggatgtgtgaggatctctggcgctggcagaagcagaat
ccttcaggctttggcacgcaagcctga
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