KEGG H.sapiens: 2597

Homo sapiens (human): 2597

Entry

2597 CDS H.sapiens

Gene name GAPDH

Definition glyceraldehyde-3-phosphate dehydrogenase (EC:1.2.1.12)

Orthology K00134 glyceraldehyde 3-phosphate dehydrogenase [EC:1.2.1.12]

Pathway hsa00010 Glycolysis / Gluconeogenesis
hsa01100 Metabolic pathways
hsa05010 Alzheimer's disease

Class Metabolism; Carbohydrate Metabolism; Glycolysis / Gluconeogenesis
[PATH:hsa00010]
Human Diseases; Neurodegenerative Diseases; Alzheimer's disease
[PATH:hsa05010]

SSDB

Motif Pfam: Gp_dh_C Gp_dh_N DapB_N
PROSITE: GAPDH

Other DBs NCBI-GI: 7669492
NCBI-GeneID: 2597
OMIM: 138400
HGNC: 4141
HPRD: 00713
Ensembl: ENSG00000111640
UniProt: P04406

Structure

PDB: 1U8F 1ZNQ

Position 12p13

AA seq 335 aa
MGKVKVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTV
KAENGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVI
ISAPSADAPMFVMGVNHEKYDNSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHA
ITATQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTANV
SVVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDAGAG
IALNDHFVKLISWYDNEFGYSNRVVDLMAHMASKE

NT seq 1008 nt +upstreamnt +downstreamnt
atggggaaggtgaaggtcggagtcaacggatttggtcgtattgggcgcctggtcaccagg
gctgcttttaactctggtaaagtggatattgttgccatcaatgaccccttcattgacctc
aactacatggtttacatgttccaatatgattccacccatggcaaattccatggcaccgtc
aaggctgagaacgggaagcttgtcatcaatggaaatcccatcaccatcttccaggagcga
gatccctccaaaatcaagtggggcgatgctggcgctgagtacgtcgtggagtccactggc
gtcttcaccaccatggagaaggctggggctcatttgcaggggggagccaaaagggtcatc
atctctgccccctctgctgatgcccccatgttcgtcatgggtgtgaaccatgagaagtat
gacaacagcctcaagatcatcagcaatgcctcctgcaccaccaactgcttagcacccctg
gccaaggtcatccatgacaactttggtatcgtggaaggactcatgaccacagtccatgcc
atcactgccacccagaagactgtggatggcccctccgggaaactgtggcgtgatggccgc
ggggctctccagaacatcatccctgcctctactggcgctgccaaggctgtgggcaaggtc
atccctgagctgaacgggaagctcactggcatggccttccgtgtccccactgccaacgtg
tcagtggtggacctgacctgccgtctagaaaaacctgccaaatatgatgacatcaagaag
gtggtgaagcaggcgtcggagggccccctcaagggcatcctgggctacactgagcaccag
gtggtctcctctgacttcaacagcgacacccactcctccacctttgacgctggggctggc
attgccctcaacgaccactttgtcaagctcatttcctggtatgacaacgaatttggctac
agcaacagggtggtggacctcatggcccacatggcctccaaggagtaa

All links

Pathway (3)   
   KEGG PATHWAY (3)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (13)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (5)   
   UNIGENE (3)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
Protein sequence (14)   
   UniProt (1)   
   RefSeq(pep) (1)   
   IPI (12)   
DNA sequence (9)   
   RefSeq(nuc) (1)   
   GenBank (4)   
   EMBL (4)   
3D Structure (2)   
   PDB (2)   
Protein domain (4)   
   Pfam (3)   
   PROSITE (1)   
All databases (48)

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