KEGG T01001: 2872

Homo sapiens (human): 2872

Entry

2872 CDS T01001

Gene name

MKNK2, GPRK7, MNK2

Definition

MAP kinase interacting serine/threonine kinase 2 (EC:2.7.11.1)

Orthology

K04372

MAP kinase interacting serine/threonine kinase [EC:2.7.11.1]

Organism

hsa Homo sapiens (human)

Pathway

hsa04010	MAPK signaling pathway
hsa04066	HIF-1 signaling pathway
hsa04910	Insulin signaling pathway

Class

Environmental Information Processing; Signal transduction; MAPK signaling pathway [PATH:hsa04010]
Environmental Information Processing; Signal transduction; HIF-1 signaling pathway [PATH:hsa04066]
Organismal Systems; Endocrine system; Insulin signaling pathway [PATH:hsa04910]

SSDB

Motif

Pfam:

Pkinase Pkinase_Tyr Kdo

Other DBs

NCBI-GI:

NCBI-GeneID:

OMIM:

HGNC:

HPRD:

Ensembl:

Vega:

UniProt:

Structure

PDB:

2AC3 2HW7 2AC5

Position

19p13.3

AA seq 414 aa
MVQKKPAELQGFHRSFKGQNPFELAFSLDQPDHGDSDFGLQCSARPDMPASQPIDIPDAK
KRGKKKKRGRATDSFSGRFEDVYQLQEDVLGEGAHARVQTCINLITSQEYAVKIIEKQPG
HIRSRVFREVEMLYQCQGHRNVLELIEFFEEEDRFYLVFEKMRGGSILSHIHKRRHFNEL
EASVVVQDVASALDFLHNKGIAHRDLKPENILCEHPNQVSPVKICDFDLGSGIKLNGDCS
PISTPELLTPCGSAEYMAPEVVEAFSEEASIYDKRCDLWSLGVILYILLSGYPPFVGRCG
SDCGWDRGEACPACQNMLFESIQEGKYEFPDKDWAHISCAAKDLISKLLVRDAKQRLSAA
QVLQHPWVQGCAPENTLPTPMVLQRWDSHFLLPPHPCRIHVRPGGLVRTVTVNE

NT seq 1245 nt +upstreamnt +downstreamnt
atggtgcagaagaaaccagccgaacttcagggtttccaccgttcgttcaaggggcagaac
cccttcgagctggccttctccctagaccagcccgaccacggagactctgactttggcctg
cagtgctcagcccgccctgacatgcccgccagccagcccattgacatcccggacgccaag
aagaggggcaagaagaagaagcgcggccgggccaccgacagcttctcgggcaggtttgaa
gacgtctaccagctgcaggaagatgtgctgggggagggcgctcatgcccgagtgcagacc
tgcatcaacctgatcaccagccaggagtacgccgtcaagatcattgagaagcagccaggc
cacattcggagcagggttttcagggaggtggagatgctgtaccagtgccagggacacagg
aacgtcctagagctgattgagttcttcgaggaggaggaccgcttctacctggtgtttgag
aagatgcggggaggctccatcctgagccacatccacaagcgccggcacttcaacgagctg
gaggccagcgtggtggtgcaggacgtggccagcgccttggactttctgcataacaaaggc
atcgcccacagggacctaaagccggaaaacatcctctgtgagcaccccaaccaggtctcc
cccgtgaagatctgtgacttcgacctgggcagcggcatcaaactcaacggggactgctcc
cctatctccaccccggagctgctcactccgtgcggctcggcggagtacatggccccggag
gtagtggaggccttcagcgaggaggctagcatctacgacaagcgctgcgacctgtggagc
ctgggcgtcatcttgtatatcctactcagcggctacccgcccttcgtgggccgctgtggc
agcgactgcggctgggaccgcggcgaggcctgccctgcctgccagaacatgctgtttgag
agcatccaggagggcaagtacgagttccccgacaaggactgggcccacatctcctgcgct
gccaaagacctcatctccaagctgctggtccgtgacgccaagcagaggctgagtgccgcc
caagtcctgcagcacccctgggttcaggggtgcgccccggagaacaccttgcccactccc
atggtcctgcagaggtgggacagtcacttcctcctccctccccacccctgtcgcatccac
gtgcgacctggaggactggtcagaaccgttactgtgaatgagtga

All links

Pathway (3)   
   KEGG PATHWAY (3)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (22)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (14)   
   UniGene (1)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
   OC (1)   
   VEGA (1)   
Protein sequence (4)   
   UniProt (2)   
   RefSeq(pep) (2)   
DNA sequence (46)   
   RefSeq(nuc) (2)   
   GenBank (22)   
   EMBL (22)   
3D Structure (3)   
   PDB (3)   
Protein domain (3)   
   Pfam (3)   
All databases (84)   

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