KEGG H.sapiens: 3028

Homo sapiens (human): 3028

Entry

3028 CDS H.sapiens

Gene name HSD17B10

Definition hydroxysteroid (17-beta) dehydrogenase 10 (EC:1.1.1.35 1.1.1.178)

Orthology K08683 3-hydroxyacyl-CoA dehydrogenase /
3-hydroxy-2-methylbutyryl-CoA dehydrogenase [EC:1.1.1.35
1.1.1.178]

Pathway hsa00280 Valine, leucine and isoleucine degradation
hsa01100 Metabolic pathways
hsa05010 Alzheimer's disease

Class Metabolism; Amino Acid Metabolism; Valine, leucine and isoleucine
degradation [PATH:hsa00280]
Human Diseases; Neurodegenerative Diseases; Alzheimer's disease
[PATH:hsa05010]

SSDB

Motif Pfam: adh_short KR Epimerase rpo132
PROSITE: ADH_SHORT

Other DBs NCBI-GI: 83715985
NCBI-GeneID: 3028
OMIM: 300256
HGNC: 4800
HPRD: 02223
Ensembl: ENSG00000072506
UniProt: Q99714

Structure

PDB: 2O23 1U7T 1SO8

Position Xp11.2

AA seq 252 aa
MAAACRSVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVF
APADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDV
NLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTL
PIARDLAPIGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQAIIENPFLNGE
VIRLDGAIRMQP

NT seq 759 nt +upstreamnt +downstreamnt
atggcagcagcgtgtcggagcgtgaagggcctggtggcggtaataaccggaggagcctcg
ggcctgggcctggccacggcggagcgacttgtggggcagggagcctctgctgtgcttctg
gacctgcccaactcgggtggggaggcccaagccaagaagttaggaaacaactgcgttttc
gccccagccgacgtgacctctgagaaggatgtgcaaacagctctggctctagcaaaagga
aagtttggccgtgtggatgtagctgtcaactgtgcaggcatcgcggtggctagcaagacg
tacaacttaaagaagggccagacccataccttggaagacttccagcgagttcttgatgtg
aatctcatgggcaccttcaatgtgatccgcctggtggctggtgagatgggccagaatgaa
ccagaccagggaggccaacgtggggtcatcatcaacactgccagtgtggctgccttcgag
ggtcaggttggacaagctgcatactctgcttccaaggggggaatagtgggcatgacactg
cccattgctcgggatctggctcccataggtctgtttggcaccccactgctgaccagcctc
ccagagaaagtgtgcaacttcttggccagccaagtgcccttccctagccgactgggtgac
cctgctgagtatgctcacctcgtacaggccatcatcgagaacccattcctcaatggagag
gtcatccggctggatggggccattcgtatgcagccttga

All links

Pathway (3)   
   KEGG PATHWAY (3)   
Disease (1)   
   OMIM (1)   
Chemical reaction (2)   
   KEGG ENZYME (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (14)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (8)   
   UNIGENE (1)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
Protein sequence (6)   
   UniProt (1)   
   RefSeq(pep) (2)   
   IPI (3)   
DNA sequence (8)   
   RefSeq(nuc) (2)   
   GenBank (3)   
   EMBL (3)   
3D Structure (3)   
   PDB (3)   
Protein domain (5)   
   Pfam (4)   
   PROSITE (1)   
All databases (43)

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