KEGG   Homo sapiens (human): 3033Help
Entry
3033              CDS       H.sapiens                              
Gene name HADH
Definition hydroxyacyl-Coenzyme A dehydrogenase (EC:1.1.1.35)
Orthology K00022  3-hydroxyacyl-CoA dehydrogenase [EC:1.1.1.35]
Pathway hsa00062  Fatty acid elongation in mitochondria
hsa00071  Fatty acid metabolism
hsa00280  Valine, leucine and isoleucine degradation
hsa00310  Lysine degradation
hsa00380  Tryptophan metabolism
hsa00650  Butanoate metabolism
hsa01100  Metabolic pathways
Class Metabolism; Carbohydrate Metabolism; Butanoate metabolism
[PATH:hsa00650]
Metabolism; Lipid Metabolism; Fatty acid elongation in mitochondria
[PATH:hsa00062]
Metabolism; Lipid Metabolism; Fatty acid metabolism [PATH:hsa00071]
Metabolism; Amino Acid Metabolism; Valine, leucine and isoleucine
degradation [PATH:hsa00280]
Metabolism; Amino Acid Metabolism; Lysine degradation
[PATH:hsa00310]
Metabolism; Amino Acid Metabolism; Tryptophan metabolism
[PATH:hsa00380]
BRITE hierarchy
SSDB OrthologParalogGene clusterGFIT
Motif Pfam: 3HCDH_N 3HCDH DAO NAD_Gly3P_dh_N AlaDh_PNT_C Pyr_redox
      UDPG_MGDP_dh_N NAD_binding_2 Pyr_redox_2 GIDA F420_oxidored
      2-Hacid_dh_C HI0933_like Saccharop_dh TrkA_N
PROSITE: 3HCDH
Motif
Other DBs NCBI-GI: 94557308
NCBI-GeneID: 3033
OMIM: 601609
HGNC: 4799
Ensembl: ENSG00000138796
UniProt: Q16836
Structure
PDB: 1F0Y 3HAD 1M76 1IL0 2HDH 1M75 1F14 1F17
     1F12 1LSJ 1LSO
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Jmol
Position 4q22-q26
AA seq 314 aa AA seqDB search
MAFVTRQFMRSVSSSSTASASAKKIIVKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTE
DILAKSKKGIEESLRKVAKKKFAENLKAGDEFVEKTLSTIATSTDAASVVHSTDLVVEAI
VENLKVKNELFKRLDKFAAEHTIFASNTSSLQITSIANATTRQDRFAGLHFFNPVPVMKL
VEVIKTPMTSQKTFESLVDFSKALGKHPVSCKDTPGFIVNRLLVPYLMEAIRLYERGDAS
KEDIDTAMKLGAGYPMGPFELLDYVGLDTTKFIVDGWHEMDAENPLHQPSPSLNKLVAEN
KFGKKTGEGFYKYK
NT seq 945 nt NT seq  +upstreamnt  +downstreamnt
atggccttcgtcaccaggcagttcatgcgttccgtgtcctcctcgtccaccgcctcggcc
tcggccaagaagataatcgtcaagcacgtgacggtcatcggcggcgggctgatgggcgcc
ggcattgcccaggttgctgcagcaactggtcacacagtagtgttggtagaccagacagag
gacatcctggcaaaatccaaaaagggaattgaggaaagccttaggaaagtggcaaagaag
aagtttgcagaaaaccttaaggccggcgatgaatttgtggagaagaccctgagcaccata
gcgaccagcacggatgcagcctccgttgtccacagcacagacttggtggtggaagccatc
gtggagaatctgaaggtgaaaaacgagctcttcaaaaggctggacaagtttgctgctgaa
catacaatctttgccagcaacacttcctccttgcagattacaagcatagctaatgccacc
accagacaagaccgattcgctggcctccatttcttcaacccagtgcctgtcatgaaactt
gtggaggtcattaaaacaccaatgaccagccagaagacatttgaatctttggtagacttt
agcaaagccctaggaaagcatcctgtttcttgcaaggacactcctgggtttattgtgaac
cgcctcctggttccatacctcatggaagcaatcaggctgtatgaacgaggtgacgcatcc
aaagaagacattgacactgctatgaaattaggagccggttaccccatgggcccatttgag
cttctagattatgtcggactggatactacgaagttcatcgtggatgggtggcatgaaatg
gatgcagagaacccattacatcagcccagcccatccttaaataagctggtagcagagaac
aagttcggcaagaagactggagaaggattttacaaatacaagtga
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