KEGG H.sapiens: 3291

Homo sapiens (human): 3291

Entry

3291 CDS H.sapiens

Gene name HSD11B2

Definition hydroxysteroid (11-beta) dehydrogenase 2 (EC:1.1.1.146)

Orthology K00071 11beta-hydroxysteroid dehydrogenase [EC:1.1.1.146]

Pathway hsa00140 Steroid hormone biosynthesis
hsa01100 Metabolic pathways
hsa04960 Aldosterone-regulated sodium reabsorption

Class Metabolism; Lipid Metabolism; Steroid hormone biosynthesis
[PATH:hsa00140]
Organismal Systems; Excretory System; Aldosterone-regulated sodium
reabsorption [PATH:hsa04960]

SSDB

Motif Pfam: adh_short DUF1776
PROSITE: ADH_SHORT

Other DBs NCBI-GI: 119392083
NCBI-GeneID: 3291
OMIM: 218030
HGNC: 5209
HPRD: 01958
Ensembl: ENSG00000176387
UniProt: P80365

Position 16q22

AA seq 405 aa
MERWPWPSGGAWLLVAARALLQLLRSDLRLGRPLLAALALLAALDWLCQRLLPPPAALAV
LAAAGWIALSRLARPQRLPVATRAVLITGCDSGFGKETAKKLDSMGFTVLATVLELNSPG
AIELRTCCSPRLRLLQMDLTKPGDISRVLEFTKAHTTSTGLWGLVNNAGHNEVVADAELS
PVATFRSCMEVNFFGALELTKGLLPLLRSSRGRIVTVGSPAGDMPYPCLGAYGTSKAAVA
LLMDTFSCELLPWGVKVSIIQPGCFKTESVRNVGQWEKRKQLLLANLPQELLQAYGKDYI
EHLHGQFLHSLRLAMSDLTPVVDAITDALLAARPRRRYYPGQGLGLMYFIHYYLPEGLRR
RFLQAFFISHCLPRALQPGQPGTTPPQDAAQDPNLSPGPSPAVAR

NT seq 1218 nt +upstreamnt +downstreamnt
atggagcgctggccttggccgtcgggcggcgcctggctgctcgtggctgcccgcgcgctg
ctgcagctgctgcgctcagacctgcgtctgggccgcccgctgctggcggcgctggcgctg
ctggccgcgctcgactggctgtgccagcgcctgctgcccccgccggccgcactcgccgtg
ctggccgccgccggctggatcgcgttgtcccgcctggcgcgcccgcagcgcctgccggtg
gccactcgcgcggtgctcatcaccggctgtgactctggttttggcaaggagacggccaag
aaactggactccatgggcttcacggtgctggccaccgtattggagttgaacagccccggt
gccatcgagctgcgtacctgctgctcccctcgcctaaggctgctgcagatggacctgacc
aaaccaggagacattagccgcgtgctagagttcaccaaggcccacaccaccagcaccggc
ctgtggggcctcgtcaacaacgcaggccacaatgaagtagttgctgatgcggagctgtct
ccagtggccactttccgtagctgcatggaggtgaatttctttggcgcgctcgagctgacc
aagggcctcctgcccctgctgcgcagctcaaggggccgcatcgtgactgtggggagccca
gcgggggacatgccatatccgtgcttgggggcctatggaacctccaaagcggccgtggcg
ctactcatggacacattcagctgtgaactccttccctggggggtcaaggtcagcatcatc
cagcctggctgcttcaagacagagtcagtgagaaacgtgggtcagtgggaaaagcgcaag
caattgctgctggccaacctgcctcaagagctgctgcaggcctacggcaaggactacatc
gagcacttgcatgggcagttcctgcactcgctacgcctggccatgtccgacctcacccca
gttgtagatgccatcacagatgcgctgctggcagctcggccccgccgccgctattacccc
ggccagggcctggggctcatgtacttcatccactactacctgcctgaaggcctgcggcgc
cgcttcctgcaggccttcttcatcagtcactgtctgcctcgagcactgcagcctggccag
cctggcactaccccaccacaggacgcagcccaggacccaaacctgagccccggcccttcc
ccagcagtggctcggtga

All links

Pathway (3)   
   KEGG PATHWAY (3)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (12)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (6)   
   UNIGENE (1)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
Protein sequence (3)   
   UniProt (1)   
   RefSeq(pep) (1)   
   IPI (1)   
DNA sequence (13)   
   RefSeq(nuc) (1)   
   GenBank (6)   
   EMBL (6)   
Protein domain (3)   
   Pfam (2)   
   PROSITE (1)   
All databases (37)

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