| Entry |
|
|---|
| Symbol |
HSPA8, HEL-33, HEL-S-72p, HSC54, HSC70, HSC71, HSP71, HSP73, HSPA10, LAP-1, LAP1, NIP71
|
|---|
| Name |
(RefSeq) heat shock protein family A (Hsp70) member 8
|
|---|
| KO |
| K03283 | heat shock 70kDa protein 1/6/8 |
|
|---|
| Organism |
|
|---|
| Pathway |
| hsa04141 | Protein processing in endoplasmic reticulum |
| hsa04213 | Longevity regulating pathway - multiple species |
| hsa04612 | Antigen processing and presentation |
|
|---|
| Brite |
KEGG Orthology (KO) [BR:hsa00001]
09120 Genetic Information Processing
09121 Transcription
03040 Spliceosome
3312 (HSPA8)
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
3312 (HSPA8)
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
3312 (HSPA8)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
3312 (HSPA8)
09150 Organismal Systems
09151 Immune system
04612 Antigen processing and presentation
3312 (HSPA8)
09152 Endocrine system
04915 Estrogen signaling pathway
3312 (HSPA8)
09149 Aging
04213 Longevity regulating pathway - multiple species
3312 (HSPA8)
09160 Human Diseases
09172 Infectious disease: viral
05162 Measles
3312 (HSPA8)
09171 Infectious disease: bacterial
05134 Legionellosis
3312 (HSPA8)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
3312 (HSPA8)
09164 Neurodegenerative disease
05020 Prion disease
3312 (HSPA8)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
3312 (HSPA8)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:hsa01009]
3312 (HSPA8)
09182 Protein families: genetic information processing
03041 Spliceosome [BR:hsa03041]
3312 (HSPA8)
03009 Ribosome biogenesis [BR:hsa03009]
3312 (HSPA8)
03110 Chaperones and folding catalysts [BR:hsa03110]
3312 (HSPA8)
04131 Membrane trafficking [BR:hsa04131]
3312 (HSPA8)
03051 Proteasome [BR:hsa03051]
3312 (HSPA8)
03029 Mitochondrial biogenesis [BR:hsa03029]
3312 (HSPA8)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:hsa04147]
3312 (HSPA8)
Protein phosphatases and associated proteins [BR:hsa01009]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-5
PP5-interacting proteins
3312 (HSPA8)
Spliceosome [BR:hsa03041]
Complex B
Other components
Prp19 complex
3312 (HSPA8)
Complex C
Prp19-CDC5 complex
3312 (HSPA8)
Ribosome biogenesis [BR:hsa03009]
Eukaryotic type
Pre-60S particles
Export and cytoplasmic maturation factors
3312 (HSPA8)
Chaperones and folding catalysts [BR:hsa03110]
Heat shock proteins
HSP70 / DNAK
3312 (HSPA8)
Membrane trafficking [BR:hsa04131]
Endocytosis
Clathrin-mediated endocytosis
Other core components
3312 (HSPA8)
Autophagy
Chaperone mediated autophagy (CMA)
Chaperones
3312 (HSPA8)
Proteasome [BR:hsa03051]
Eukaryotic proteasome
Assembling factors
Other assembling factors
3312 (HSPA8)
Mitochondrial biogenesis [BR:hsa03029]
Mitochondrial protein import machinery
Endoplasmic reticulum membrane and cytosol
Other ER-memrane and cytosol factors
3312 (HSPA8)
Exosome [BR:hsa04147]
Exosomal proteins
Proteins found in most exosomes
3312 (HSPA8)
|
|---|
| SSDB |
|
|---|
| Motif |
|
|---|
| Other DBs |
|
|---|
| Structure |
|
|---|
| Position |
11:complement(123057489..123062462)
|
|---|
| AA seq |
646 aa
MSKGPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVA
MNPTNTVFDAKRLIGRRFDDAVVQSDMKHWPFMVVNDAGRPKVQVEYKGETKSFYPEEVS
SMVLTKMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAA
IAYGLDKKVGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNH
FIAEFKRKHKKDISENKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGIDFYTSITRA
RFEELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKELN
KSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRNTTI
PTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTGIPPAPRGVPQIEVTFDI
DANGILNVSAVDKSTGKENKITITNDKGRLSKEDIERMVQEAEKYKAEDEKQRDKVSSKN
SLESYAFNMKATVEDEKLQGKINDEDKQKILDKCNEIINWLDKNQTAEKEEFEHQQKELE
KVCNPIITKLYQSAGGMPGGMPGGFPGGGAPPSGGASSGPTIEEVD |
|---|
| NT seq |
1941 nt +upstreamnt +downstreamnt
atgtccaagggacctgcagttggtattgatcttggcaccacctactcttgtgtgggtgtt
ttccagcacggaaaagtcgagataattgccaatgatcagggaaaccgaaccactccaagc
tatgtcgcctttacggacactgaacggttgatcggtgatgccgcaaagaatcaagttgca
atgaaccccaccaacacagtttttgatgccaaacgtctgattggacgcagatttgatgat
gctgttgtccagtctgatatgaaacattggccctttatggtggtgaatgatgctggcagg
cccaaggtccaagtagaatacaagggagagaccaaaagcttctatccagaggaggtgtct
tctatggttctgacaaagatgaaggaaattgcagaagcctaccttgggaagactgttacc
aatgctgtggtcacagtgccagcttactttaatgactctcagcgtcaggctaccaaagat
gctggaactattgctggtctcaatgtacttagaattattaatgagccaactgctgctgct
attgcttacggcttagacaaaaaggttggagcagaaagaaacgtgctcatctttgacctg
ggaggtggcacttttgatgtgtcaatcctcactattgaggatggaatctttgaggtcaag
tctacagctggagacacccacttgggtggagaagattttgacaaccgaatggtcaaccat
tttattgctgagtttaagcgcaagcataagaaggacatcagtgagaacaagagagctgta
agacgcctccgtactgcttgtgaacgtgctaagcgtaccctctcttccagcacccaggcc
agtattgagatcgattctctctatgaaggaatcgacttctatacctccattacccgtgcc
cgatttgaagaactgaatgctgacctgttccgtggcaccctggacccagtagagaaagcc
cttcgagatgccaaactagacaagtcacagattcatgatattgtcctggttggtggttct
actcgtatccccaagattcagaagcttctccaagacttcttcaatggaaaagaactgaat
aagagcatcaaccctgatgaagctgttgcttatggtgcagctgtccaggcagccatcttg
tctggagacaagtctgagaatgttcaagatttgctgctcttggatgtcactcctctttcc
cttggtattgaaactgctggtggagtcatgactgtcctcatcaagcgtaataccaccatt
cctaccaagcagacacagaccttcactacctattctgacaaccagcctggtgtgcttatt
caggtttatgaaggcgagcgtgccatgacaaaggataacaacctgcttggcaagtttgaa
ctcacaggcatacctcctgcaccccgaggtgttcctcagattgaagtcacttttgacatt
gatgccaatggtatactcaatgtctctgctgtggacaagagtacgggaaaagagaacaag
attactatcactaatgacaagggccgtttgagcaaggaagacattgaacgtatggtccag
gaagctgagaagtacaaagctgaagatgagaagcagagggacaaggtgtcatccaagaat
tcacttgagtcctatgccttcaacatgaaagcaactgttgaagatgagaaacttcaaggc
aagattaacgatgaggacaaacagaagattctggacaagtgtaatgaaattatcaactgg
cttgataagaatcagactgctgagaaggaagaatttgaacatcaacagaaagagctggag
aaagtttgcaaccccatcatcaccaagctgtaccagagtgcaggaggcatgccaggagga
atgcctgggggatttcctggtggtggagctcctccctctggtggtgcttcctcagggccc
accattgaagaggttgattaa |
|---|
