KEGG H.sapiens: 3418

Homo sapiens (human): 3418

Entry

3418 CDS H.sapiens

Gene name IDH2

Definition isocitrate dehydrogenase 2 (NADP+), mitochondrial (EC:1.1.1.42)

Orthology K00031 isocitrate dehydrogenase [EC:1.1.1.42]

Pathway hsa00020 Citrate cycle (TCA cycle)
hsa00480 Glutathione metabolism
hsa01100 Metabolic pathways
hsa04146 Peroxisome

Class Metabolism; Carbohydrate Metabolism; Citrate cycle (TCA cycle)
[PATH:hsa00020]
Metabolism; Metabolism of Other Amino Acids; Glutathione metabolism
[PATH:hsa00480]
Cellular Processes; Transport and Catabolism; Peroxisome
[PATH:hsa04146]

SSDB

Motif Pfam: Iso_dh
PROSITE: IDH_IMDH

Other DBs NCBI-GI: 28178832
NCBI-GeneID: 3418
OMIM: 147650
HGNC: 5383
HPRD: 00973
Ensembl: ENSG00000182054
UniProt: P48735

Position 15q26.1

AA seq 452 aa
MAGYLRVVRSLCRASGSRPAWAPAALTAPTSQEQPRRHYADKRIKVAKPVVEMDGDEMTR
IIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTDDQVTIDSALATQKYSVAVKCATITPDE
ARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVPGWTKPITIGRHAHGDQYK
ATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFPAGGVGMGMYNTDESISGFAHSCFQYAI
QKKWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYKTDFDKNKIWYEHRLIDDMVAQVLKS
SGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHYREHQK
GRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQMLEKVCVETVESGAMTKDLAGCIH
GLSNVKLNEHFLNTTDFLDTIKSNLDRALGRQ

NT seq 1359 nt +upstreamnt +downstreamnt
atggccggctacctgcgggtcgtgcgctcgctctgcagagcctcaggctcgcggccggcc
tgggcgccggcggccctgacagcccccacctcgcaagagcagccgcggcgccactatgcc
gacaaaaggatcaaggtggcgaagcccgtggtggagatggatggtgatgagatgacccgt
attatctggcagttcatcaaggagaagctcatcctgccccacgtggacatccagctaaag
tattttgacctcgggctcccaaaccgtgaccagactgatgaccaggtcaccattgactct
gcactggccacccagaagtacagtgtggctgtcaagtgtgccaccatcacccctgatgag
gcccgtgtggaagagttcaagctgaagaagatgtggaaaagtcccaatggaactatccgg
aacatcctgggggggactgtcttccgggagcccatcatctgcaaaaacatcccacgccta
gtccctggctggaccaagcccatcaccattggcaggcacgcccatggcgaccagtacaag
gccacagactttgtggcagaccgggccggcactttcaaaatggtcttcaccccaaaagat
ggcagtggtgtcaaggagtgggaagtgtacaacttccccgcaggcggcgtgggcatgggc
atgtacaacaccgacgagtccatctcaggttttgcgcacagctgcttccagtatgccatc
cagaagaaatggccgctgtacatgagcaccaagaacaccatactgaaagcctacgatggg
cgtttcaaggacatcttccaggagatctttgacaagcactataagaccgacttcgacaag
aataagatctggtatgagcaccggctcattgatgacatggtggctcaggtcctcaagtct
tcgggtggctttgtgtgggcctgcaagaactatgacggagatgtgcagtcagacatcctg
gcccagggctttggctcccttggcctgatgacgtccgtcctggtctgccctgatgggaag
acgattgaggctgaggccgctcatgggaccgtcacccgccactatcgggagcaccagaag
ggccggcccaccagcaccaaccccatcgccagcatctttgcctggacacgtggcctggag
caccgggggaagctggatgggaaccaagacctcatcaggtttgcccagatgctggagaag
gtgtgcgtggagacggtggagagtggagccatgaccaaggacctggcgggctgcattcac
ggcctcagcaatgtgaagctgaacgagcacttcctgaacaccacggacttcctcgacacc
atcaagagcaacctggacagagccctgggcaggcagtag

All links

Pathway (4)   
   KEGG PATHWAY (4)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (9)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (3)   
   UNIGENE (1)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
Protein sequence (4)   
   UniProt (1)   
   RefSeq(pep) (1)   
   IPI (2)   
DNA sequence (7)   
   RefSeq(nuc) (1)   
   GenBank (3)   
   EMBL (3)   
Protein domain (2)   
   Pfam (1)   
   PROSITE (1)   
All databases (29)

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