KEGG H.sapiens: 3707

Homo sapiens (human): 3707

Entry

3707 CDS H.sapiens

Gene name ITPKB

Definition inositol 1,4,5-trisphosphate 3-kinase B (EC:2.7.1.127)

Orthology K00911 1D-myo-inositol-triphosphate 3-kinase [EC:2.7.1.127]

Pathway hsa00562 Inositol phosphate metabolism
hsa01100 Metabolic pathways
hsa04020 Calcium signaling pathway
hsa04070 Phosphatidylinositol signaling system

Class Metabolism; Carbohydrate Metabolism; Inositol phosphate metabolism
[PATH:hsa00562]
Environmental Information Processing; Signal Transduction; Calcium
signaling pathway [PATH:hsa04020]
Environmental Information Processing; Signal Transduction;
Phosphatidylinositol signaling system [PATH:hsa04070]

SSDB

Motif Pfam: IPK
PROSITE: SER_RICH

Other DBs NCBI-GI: 194272161
NCBI-GeneID: 3707
OMIM: 147522
HGNC: 6179
HPRD: 00942
Ensembl: ENSG00000143772
UniProt: B2R9J0 P27987

Position 1q42.13

AA seq 946 aa
MAVYCYALNSLVIMNSANEMKSGGGPGPSGSETPPPPRRAVLSPGSVFSPGRGASFLFPP
AESLSPEEPRSPGGWRSGRRRLNSSSGSGSGSSGSSVSSPSWAGRLRGDRQQVVAAGTLS
PPGPEEAKRKLRILQRELQNVQVNQKVGMFEAHIQAQSSAIQAPRSPRLGRARSPSPCPF
RSSSQPPGRVLVQGARSEERRTKSWGEQCPETSGTDSGRKGGPSLCSSQVKKGMPPLPGR
AAPTGSEAQGPSAFVRMEKGIPASPRCGSPTAMEIDKRGSPTPGTRSCLAPSLGLFGASL
TMATEVAARVTSTGPHRPQDLALTEPSGRARELEDLQPPEALVERQGQFLGSETSPAPER
GGPRDGEPPGKMGKGYLPCGMPGSGEPEVGKRPEETTVSVQSAESSDSLSWSRLPRALAS
VGPEEARSGAPVGGGRWQLSDRVEGGSPTLGLLGGSPSAQPGTGNVEAGIPSGRMLEPLP
CWDAAKDLKEPQCPPGDRVGVQPGNSRVWQGTMEKAGLAWTRGTGVQSEGTWESQRQDSD
ALPSPELLPQDPDKPFLRKACSPSNIPAVIITDMGTQEDGALEETQGSPRGNLPLRKLSS
SSASSTGFSSSYEDSEEDISSDPERTLDPNSAFLHTLDQQKPRVSKSWRKIKNMVHWSPF
VMSFKKKYPWIQLAGHAGSFKAAANGRILKKHCESEQRCLDRLMVDVLRPFVPAYHGDVV
KDGERYNQMDDLLADFDSPCVMDCKMGIRTYLEEELTKARKKPSLRKDMYQKMIEVDPEA
PTEEEKAQRAVTKPRYMQWRETISSTATLGFRIEGIKKEDGTVNRDFKKTKTREQVTEAF
REFTKGNHNILIAYRDRLKAIRTTLEVSPFFKCHEVIGSSLLFIHDKKEQAKVWMIDFGK
TTPLPEGQTLQHDVPWQEGNREDGYLSGLNNLVDILTEMSQDAPLA

NT seq 2841 nt +upstreamnt +downstreamnt
atggctgtgtactgctatgcgctcaatagcctggtgatcatgaatagcgccaacgagatg
aagagcggcggcggcccggggcccagtggcagcgagacgcccccgcccccgaggagggca
gtgctgagccccggcagcgttttcagccccgggagaggcgcctctttcctcttcccccca
gccgagtcgctgtcccccgaggagccccggagccccgggggctggcggagcggccggcgc
aggctgaatagtagcagcggcagtggcagcggcagcagcggcagtagcgtgagcagccca
agttgggctggtcgcctgcgaggggaccggcagcaggtggtggcagccggtaccctctcc
ccgccagggccggaggaggccaagaggaagctgcggatcttgcagcgcgagttgcagaac
gtgcaggtgaaccagaaagtgggcatgtttgaggcgcacatccaggcacagagctccgcc
attcaagcgccccgcagcccgcgtttgggcagggctcgctcgccctccccgtgccccttc
cgcagcagcagtcagccccctggaagggtcctggttcagggcgcccggagcgaggaacgg
aggacaaagtcctggggggagcaatgtccagagacttcaggaaccgactccgggaggaaa
ggagggcccagcctatgctcctcgcaggtgaagaaaggaatgccacctcttcccggccgg
gctgcccctacaggatcagaggctcagggtccatccgcttttgtaaggatggagaagggt
atccctgccagtccccgctgtggctcacccacagctatggaaattgacaaaaggggctct
cctaccccgggaactcggagctgcctagctccctcattggggctgttcggagctagctta
acgatggccacggaagtggcagcgagagttacatccactgggccacaccgtccacaggat
cttgccctcactgagccgtctgggagagcccgtgagcttgaggacctgcagcccccagag
gccctggtggagaggcaggggcagtttctgggcagtgagacaagcccagccccagaaagg
ggcgggccccgcgatggagaaccccctgggaagatggggaaaggatatctgccctgtggc
atgccgggctctggggagcctgaagtgggcaaaaggccagaggagacgactgtgagcgtg
caaagcgcagagtcctctgattccctgagctggtccaggctgcccagggccctggcctcc
gtaggccctgaggaggcccgaagtggggcccccgtgggcggggggcgttggcagctctcc
gacagagtggagggagggtccccaacgctgggcttgcttgggggcagcccctcagcacag
ccggggaccgggaatgtggaggcgggaattccttctggcagaatgctggagcctttgccc
tgttgggacgctgcgaaagatctgaaagaacctcagtgccctcctggggacagggtgggt
gtgcagcctgggaactccagggtttggcagggcaccatggagaaagccggtttggcttgg
acgcgtggcacaggggtgcaatcagaggggacttgggaaagccagcggcaggacagtgat
gccctcccaagtccggagctgctaccccaagatccggacaagcctttcctgaggaaggcc
tgcagccccagcaacatacctgctgtcatcattacagacatgggcacccaggaggatggg
gccttggaggagacgcagggaagccctcggggcaacctgcccctgaggaaactgtcctct
tcctcggcctcctccacgggcttctcctcatcctacgaagactcagaggaggacatctcc
agtgaccctgagcgcaccctggaccccaactcagccttcctgcataccctggaccagcag
aaacctagagtgagcaaatcatggaggaagataaaaaacatggtgcactggtctcccttc
gtcatgtccttcaagaagaagtacccctggatccagctggcaggacacgcagggagtttc
aaggcagctgccaatggcaggatcctgaagaagcactgtgagtcagagcagcgctgcctg
gaccggctgatggtggatgtgctgaggcccttcgtacctgcctaccatggggatgtggtg
aaggacggggagcgctacaaccagatggacgacctgctggccgacttcgactcgccctgt
gtgatggactgcaagatgggaatcaggacctacctggaggaggagctcacgaaggcccgg
aagaagcccagcctgcggaaggacatgtaccagaagatgatcgaggtggaccccgaggcc
cccaccgaggaggaaaaagcacagcgggctgtgaccaagccacggtacatgcagtggcgg
gagaccatcagctccacggccaccctggggttcaggatcgagggaatcaagaaagaagac
ggcaccgtgaaccgggacttcaagaagaccaaaacgagggagcaggtcaccgaggccttc
agagagttcactaaaggaaaccataacatcctgatcgcctatcgggaccggctgaaggcc
attcgaaccactctagaagtttctcccttcttcaagtgccacgaggtcattggcagctcc
ctcctcttcatccacgacaagaaggaacaggccaaagtgtggatgatcgactttgggaaa
accacgcccctgcctgagggccagaccctgcagcatgacgtcccctggcaggaggggaac
cgggaggatggctacctctcggggctcaataacctcgtcgacatcctgaccgagatgtcc
caggatgccccactcgcctga

All links

Pathway (4)   
   KEGG PATHWAY (4)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (11)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (4)   
   UNIGENE (2)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
Protein sequence (5)   
   UniProt (2)   
   RefSeq(pep) (1)   
   IPI (2)   
DNA sequence (7)   
   RefSeq(nuc) (1)   
   GenBank (3)   
   EMBL (3)   
Protein domain (2)   
   Pfam (1)   
   PROSITE (1)   
All databases (32)

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