KEGG   Homo sapiens (human): 38Help
Entry
38                CDS       H.sapiens                              
Gene name ACAT1
Definition acetyl-Coenzyme A acetyltransferase 1 (EC:2.3.1.9)
Orthology K00626  acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
Pathway hsa00071  Fatty acid metabolism
hsa00072  Synthesis and degradation of ketone bodies
hsa00280  Valine, leucine and isoleucine degradation
hsa00310  Lysine degradation
hsa00380  Tryptophan metabolism
hsa00620  Pyruvate metabolism
hsa00640  Propanoate metabolism
hsa00650  Butanoate metabolism
hsa00900  Terpenoid backbone biosynthesis
hsa01100  Metabolic pathways
Class Metabolism; Carbohydrate Metabolism; Pyruvate metabolism
[PATH:hsa00620]
Metabolism; Carbohydrate Metabolism; Propanoate metabolism
[PATH:hsa00640]
Metabolism; Carbohydrate Metabolism; Butanoate metabolism
[PATH:hsa00650]
Metabolism; Lipid Metabolism; Fatty acid metabolism [PATH:hsa00071]
Metabolism; Lipid Metabolism; Synthesis and degradation of ketone
bodies [PATH:hsa00072]
Metabolism; Amino Acid Metabolism; Valine, leucine and isoleucine
degradation [PATH:hsa00280]
Metabolism; Amino Acid Metabolism; Lysine degradation
[PATH:hsa00310]
Metabolism; Amino Acid Metabolism; Tryptophan metabolism
[PATH:hsa00380]
Metabolism; Biosynthesis of Secondary Metabolites; Terpenoid
backbone biosynthesis [PATH:hsa00900]
BRITE hierarchy
SSDB OrthologParalogGene clusterGFIT
Motif Pfam: Thiolase_N Thiolase_C ketoacyl-synt
PROSITE: THIOLASE_1 THIOLASE_2 THIOLASE_3
Motif
Other DBs NCBI-GI: 4557237
NCBI-GeneID: 38
OMIM: 607809
HGNC: 93
HPRD: 01946
Ensembl: ENSG00000075239
UniProt: P24752
Structure
PDB: 2IBY 2IB8 2IBU 2IBW 2F2S 2IB7 2IB9
     Thumbnails

Jmol
Position 11q22.3-q23.1
AA seq 427 aa AA seqDB search
MAVLAALLRSGARSRSPLLRRLVQEIRYVERSYVSKPTLKEVVIVSATRTPIGSFLGSLS
LLPATKLGSIAIQGAIEKAGIPKEEVKEAYMGNVLQGGEGQAPTRQAVLGAGLPISTPCT
TINKVCASGMKAIMMASQSLMCGHQDVMVAGGMESMSNVPYVMNRGSTPYGGVKLEDLIV
KDGLTDVYNKIHMGSCAENTAKKLNIARNEQDAYAINSYTRSKAAWEAGKFGNEVIPVTV
TVKGQPDVVVKEDEEYKRVDFSKVPKLKTVFQKENGTVTAANASTLNDGAAALVLMTADA
AKRLNVTPLARIVAFADAAVEPIDFPIAPVYAASMVLKDVGLKKEDIAMWEVNEAFSLVV
LANIKMLEIDPQKVNINGGAVSLGHPIGMSGARIVGHLTHALKQGEYGLASICNGGGGAS
AMLIQKL
NT seq 1284 nt NT seq  +upstreamnt  +downstreamnt
atggctgtgctggcggcacttctgcgcagcggcgcccgcagccgcagccccctgctccgg
aggctggtgcaggaaataagatatgtggaacggagttatgtatcaaaacccactttgaag
gaagtggtcatagtaagtgctacaagaacacccattggatcttttttaggcagcctttcc
ttgctgccagccactaagcttggttccattgcaattcagggagccattgaaaaggcaggg
attccaaaagaagaagtgaaagaagcatacatgggtaatgttctacaaggaggtgaagga
caagctcctacaaggcaggcagtattgggtgcaggcttacctatttctactccatgtacc
accataaacaaagtttgtgcttcaggaatgaaagccatcatgatggcctctcaaagtctt
atgtgtggacatcaggatgtgatggtggcaggtgggatggagagcatgtccaatgttcca
tatgtaatgaacagaggatcaacaccatatggtggggtaaagcttgaagatttgattgta
aaagacgggctaactgatgtctacaataaaattcatatgggcagctgtgctgagaataca
gcaaagaagctgaatattgcacgaaatgaacaggacgcttatgctattaattcttatacc
agaagtaaagcagcatgggaagctgggaaatttggaaatgaagttattcctgtcacagtt
acagtaaaaggtcaaccagatgtagtggtgaaagaagatgaagaatataaacgtgttgat
tttagcaaagttccaaagctgaagacagttttccagaaagaaaatggcacagtaacagct
gccaatgccagtacactgaatgatggagcagctgctctggttctcatgacggcagatgca
gcgaagaggctcaatgttacaccactggcaagaatagtagcatttgctgacgctgctgta
gaacctattgattttccaattgctcctgtatatgctgcatctatggttcttaaagatgtg
ggattgaaaaaagaagatattgcaatgtgggaagtaaatgaagcctttagtctggttgta
ctagcaaacattaaaatgttggagattgatccccaaaaagtgaatatcaatggaggagct
gtttctctgggacatccaattgggatgtctggagccaggattgttggtcatttgactcat
gccttgaagcaaggagaatacggtcttgccagtatttgcaatggaggaggaggtgcttct
gccatgctaattcagaagctgtag
DBGET integrated database retrieval system