KEGG H.sapiens: 3939

Homo sapiens (human): 3939

Entry

3939 CDS H.sapiens

Gene name LDHA

Definition lactate dehydrogenase A (EC:1.1.1.27)

Orthology K00016 L-lactate dehydrogenase [EC:1.1.1.27]

Pathway hsa00010 Glycolysis / Gluconeogenesis
hsa00270 Cysteine and methionine metabolism
hsa00620 Pyruvate metabolism
hsa00640 Propanoate metabolism
hsa01100 Metabolic pathways

Class Metabolism; Carbohydrate Metabolism; Glycolysis / Gluconeogenesis
[PATH:hsa00010]
Metabolism; Carbohydrate Metabolism; Pyruvate metabolism
[PATH:hsa00620]
Metabolism; Carbohydrate Metabolism; Propanoate metabolism
[PATH:hsa00640]
Metabolism; Amino Acid Metabolism; Cysteine and methionine
metabolism [PATH:hsa00270]

SSDB

Motif Pfam: Ldh_1_C Ldh_1_N
PROSITE: L_LDH PROKAR_LIPOPROTEIN

Other DBs NCBI-GI: 207028494
NCBI-GeneID: 3939
OMIM: 150000
HGNC: 6535
HPRD: 01025
Ensembl: ENSG00000134333
UniProt: B4DKQ2

Structure

PDB: 1I10

Position 11p15.4

AA seq 274 aa
MATLKDQLIYNLLKEEQTPQNKITVVGVGAVGMACAISILMKDLADELALVDVIEDKLKG
EMMDLQHGSLFLRTPKIVSGKVDILTYVAWKISGFPKNRVIGSGCNLDSARFRYLMGERL
GVHPLSCHGWVLGEHGDSSVPVWSGMNVAGVSLKTLHPDLGTDKDKEQWKEVHKQVVESA
YEVIKLKGYTSWAIGLSVADLAESIMKNLRRVHPVSTMIKGLYGIKDDVFLSVPCILGQN
GISDLVKVTLTSEEEARLKKSADTLWGIQKELQF

NT seq 825 nt +upstreamnt +downstreamnt
atggcaactctaaaggatcagctgatttataatcttctaaaggaagaacagaccccccag
aataagattacagttgttggggttggtgctgttggcatggcctgtgccatcagtatctta
atgaaggacttggcagatgaacttgctcttgttgatgtcatcgaagacaaattgaaggga
gagatgatggatctccaacatggcagccttttccttagaacaccaaagattgtctctggc
aaagtggatatcttgacctacgtggcttggaagataagtggttttcccaaaaaccgtgtt
attggaagcggttgcaatctggattcagcccgattccgttacctaatgggggaaaggctg
ggagttcacccattaagctgtcatgggtgggtccttggggaacatggagattccagtgtg
cctgtatggagtggaatgaatgttgctggtgtctctctgaagactctgcacccagattta
gggactgataaagataaggaacagtggaaagaggttcacaagcaggtggttgagagtgct
tatgaggtgatcaaactcaaaggctacacatcctgggctattggactctctgtagcagat
ttggcagagagtataatgaagaatcttaggcgggtgcacccagtttccaccatgattaag
ggtctttacggaataaaggatgatgtcttccttagtgttccttgcattttgggacagaat
ggaatctcagaccttgtgaaggtgactctgacttctgaggaagaggcccgtttgaagaag
agtgcagatacactttgggggatccaaaaggagctgcaattttaa

All links

Pathway (5)   
   KEGG PATHWAY (5)   
Disease (5)   
   KEGG DISEASE (4)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (11)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (5)   
   UNIGENE (1)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
Protein sequence (14)   
   UniProt (1)   
   RefSeq(pep) (5)   
   IPI (8)   
DNA sequence (11)   
   RefSeq(nuc) (5)   
   GenBank (3)   
   EMBL (3)   
3D Structure (1)   
   PDB (1)   
Protein domain (4)   
   Pfam (2)   
   PROSITE (2)   
All databases (53)

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